From Publishers Weekly
This energetic but unfocused account awkwardly merges several strands: the author's experience with the threat of breast cancer, discussions of genetic inheritance in Jewish families and a look at how the ability to test for genetic predispositions to various diseases is changing lives. With a family history of breast cancer, journalist Gessen (
Dead Again: The Russian Intelligentsia After Communism) was not surprised to learn she had inherited a deleterious mutation in the BRCA1 gene, one of two genes known to be linked to breast and ovarian cancer. The BRCA1 mutation was first discovered in Jewish women, a compact population with a higher-than-average breast cancer rate. Gessen describes her narrow options, with nondirective counseling steering her toward prophylactic removal of her breasts and ovaries. Then she jumps the track to talk about Dr. Henry Lynch, who, in 1966, first suggested that predisposition to cancer might be hereditary. Gessen also covers Huntington's disease, maple syrup disease among Old Order Mennonites, eugenics and how a genetic testing program is affecting marital choices for some Orthodox Jews. Gessen covers a fair amount of ground, but in a haphazard fashion. The book's strongest parts are on genetics and heredity in the Jewish community.
(Apr.) Copyright © Reed Business Information, a division of Reed Elsevier Inc. All rights reserved.
Review
"Blood Matters is valuable reading to almost anyone facing a huge health decision, not only for the literary commiseration it offers, but also for the inspired example of medical sleuthing on one''s own behalf that it provides ... The enduring memory one takes away is Gessen''s intelligence and wit as she''s staring down the barrel of a gun." (
The New York Times )
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