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Editorial Reviews
Amazon.com Review
It's official. Our tendencies to be happy or sad come in part from our genes. Samuel H. Barondes is a neurobiologist and psychiatrist at the University of California, San Francisco, and his direct involvement with the subject lends friendly authority to the book. Examining manic depression as a case study, Barondes shows how this strange condition--thought to have been instrumental in the ups and downs of Dickens, van Gogh, and Newton, among others--is definitely heritable. Although the specific gene or genes associated with the disorder haven't been identified, Barondes's account of the search is fascinating. --This text refers to the Hardcover edition.
From Scientific American
The search for genes that cause or contribute to disease has had many successes in recent years, and the successes come at an ever faster pace. Barondes, a psychiatrist who has treated many patients with serious mood disorders, examines here the prospects for finding genes that cause or contribute to such afflictions-in particular manic-depressive illness. "Characterized by episodic and disruptive mood fluctuations," he says, "this illness is especially important because it affects so many people-about one in a hundred of us in its most flagrant form, and possibly several times as many of us in milder versions." His tale focuses on two families in which the disease has turned up repeatedly. Having introduced the first of the families, he provides what amounts to a basic course on genes, presented so clearly as to make the reader feel almost like an expert on the subject. Barondes is optimistic that mood genes will be found, thus introducing the possibility of "tailor-made treatments for different forms" of mood disorders and of "the development of new therapeutic drugs that alleviate symptoms and prevent attacks." --This text refers to the Hardcover edition.
See all Editorial Reviews
It's official. Our tendencies to be happy or sad come in part from our genes. Samuel H. Barondes is a neurobiologist and psychiatrist at the University of California, San Francisco, and his direct involvement with the subject lends friendly authority to the book. Examining manic depression as a case study, Barondes shows how this strange condition--thought to have been instrumental in the ups and downs of Dickens, van Gogh, and Newton, among others--is definitely heritable. Although the specific gene or genes associated with the disorder haven't been identified, Barondes's account of the search is fascinating. --This text refers to the Hardcover edition.
From Scientific American
The search for genes that cause or contribute to disease has had many successes in recent years, and the successes come at an ever faster pace. Barondes, a psychiatrist who has treated many patients with serious mood disorders, examines here the prospects for finding genes that cause or contribute to such afflictions-in particular manic-depressive illness. "Characterized by episodic and disruptive mood fluctuations," he says, "this illness is especially important because it affects so many people-about one in a hundred of us in its most flagrant form, and possibly several times as many of us in milder versions." His tale focuses on two families in which the disease has turned up repeatedly. Having introduced the first of the families, he provides what amounts to a basic course on genes, presented so clearly as to make the reader feel almost like an expert on the subject. Barondes is optimistic that mood genes will be found, thus introducing the possibility of "tailor-made treatments for different forms" of mood disorders and of "the development of new therapeutic drugs that alleviate symptoms and prevent attacks." --This text refers to the Hardcover edition.
See all Editorial Reviews
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Inside This Book
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First Sentence:
When Michael was in kindergarten his mother, Flora, was overwhelmed by her first attack of mania. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
mood genes, single morbid process, sickle cell allele, human genetic map, serious mood disorder, abnormal allele, linkage approach, psychiatric genetics, unipolar disorder, causative gene Key Phrases - Capitalized Phrases (CAPs): (learn more)
Costa Rica, Central Valley, United States, Archibald Garrod, Francis Galton, Central Dogma, Michael Escamilla, Charles Darwin, Human Genome Project, Nelson Freimer, Victor Reus, Alan Stone, Alois Alzheimer, David Housman, Eduardo Fournier, Nature Genetics, University of Vienna, William Bateson New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
When Michael was in kindergarten his mother, Flora, was overwhelmed by her first attack of mania. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
mood genes, single morbid process, sickle cell allele, human genetic map, serious mood disorder, abnormal allele, linkage approach, psychiatric genetics, unipolar disorder, causative gene Key Phrases - Capitalized Phrases (CAPs): (learn more)
Costa Rica, Central Valley, United States, Archibald Garrod, Francis Galton, Central Dogma, Michael Escamilla, Charles Darwin, Human Genome Project, Nelson Freimer, Victor Reus, Alan Stone, Alois Alzheimer, David Housman, Eduardo Fournier, Nature Genetics, University of Vienna, William Bateson New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 54
books:
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14
books
cite this book:
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- The Origin Of Species: 150th Anniversary Edition by Charles Darwin on page 62, page 78, and Back Matter
- On the Origin of Species (Penguin Classics) by Charles Darwin on page 62, page 78, and Back Matter
- The Origin of Species by Charles Darwin on page 62, page 78, and Back Matter
- Manic-Depressive Insanity and Paranoia (Foundations of Modern Psychiatry) by Emil Kraepelin in Back Matter (1), and Back Matter (2)
- A History of Genetics by A. H. Sturtevant on page 104, and Back Matter
See all 54 books this book cites
- Surviving Manic Depression: A Manual on Bipolar Disorder for Patients, Families, and Providers by E. Fuller Torrey M.D. in Back Matter (1), Back Matter (2), and Back Matter (3)
- Surviving Manic Depression: A Manual on Bipolar Disorder for Patients, Families, and Providers by E. Fuller Torrey in Back Matter (1), and Back Matter (2)
- Understanding Depression: What We Know and What You Can Do About It by J. Raymond DePaulo in Back Matter (1), and Back Matter (2)
- Monkeyluv: And Other Essays on Our Lives as Animals by Robert M. Sapolsky on page 26
- The Greatest Inventions of the Past 2,000 Years by John Brockman on page 33
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