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After centuries of outsiders carping about scientific reductionism, the promised synthesis is finally on its way. Immunology, genetics, medicine, neurology, and other fields are starting to overlap more and more, and prominent neuropsychiatrist Nancy C. Andreasen explores one exciting intersection in
Brave New Brain. The author's broad understanding and straightforward writing offer readers a penetrating glimpse into new and future treatments for mental illness. Focusing on four devastating maladies (schizophrenia, bipolar disorder, anxiety disorders, and dementia), she shows what scientists have learned about them recently thanks to powerful imaging and biochemical tools. This knowledge, growing exponentially and integrated with data from diverse scientific research including the Human Genome Project, is used to propose mechanisms underlying diseases and potential cures--from genetic repair to bold new pharmacologic interventions.
Well-illustrated and lucidly explained, the book is an excellent lay primer on the brain and its disorders. Though Andreasen's prose isn't as elegant as some of her colleagues', it is clear and always to the point; many readers will appreciate the lack of distraction from the book's content. The hope she holds out to sufferers of mental illness, if not immediately promising, is certainly brighter than has been offered in recent years. Despite its moderately sinister title, Brave New Brain is an enlightening and even uplifting look at the convergence of several important scientific disciplines. --Rob Lightner
From Library Journal
Andreasen, a prolific author, editor of the American Journal of Psychiatry, and chair of psychiatry at the University of Iowa College of Medicine, argues that by combining our knowledge of the human genome with that of the human brain we can effectively "wage war" on mental illness. She summarizes what we know about the etiology, diagnosis, and treatment of schizophrenia, dementia, and various mood and anxiety disorders. Stressing that these illnesses are multifactorial (caused by both multiple genes and environmental factors), she predicts that the powerful new tools of molecular biology can be successfully applied to mental illness. Like Rita Carter in Mapping the Mind (LJ 2/15/99), which summarizes the current state of medical technology, Andreasen describes those tools along with the neuroimaging techniques that help us to view the functioning brain. Her text is unique in that it covers the fundamentals of neurobiology and at the same time touches on key issues in medical economics, treatment, and prevention. Hypothetical case studies illustrate the progression and impact of mental illness. Written with clarity and sensitivity, this study offers a refreshing, optimistic vision of the future. Suitable for public and academic libraries. Laurie Bartolini, Illinois State Lib., Springfield
Copyright 2001 Reed Business Information, Inc.
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