From Publishers Weekly
Based on the title, one might expect this to be a consumer health book offering cutting-edge stress-fighting techniques. Instead, brain researcher McEwen, who heads a neuroendocrinology lab at New York's Rockefeller University, presents a science text for laypeople who want to understand how brain biochemistry is altered during times of stress. He wrote the book to illustrate the paradox that "stress protects under acute conditions, but when activated chronically it can cause damage and accelerate disease." He illustrates this point by surveying some 50 years of lab research on how hormones and the immune system interact during temporary and chronic stress in people, animals and even tree shrews. In everyday terms, this syndrome is known as the "fight or flight response," but McEwen prefers the term "allostasis" for temporary stress and "allostatic" for chronic stress. Some of the studies are more intriguing than others (e.g., the chapter on voodoo death is infinitely more readable than discussions of immune function in distressed lab rats). A detailed appendix with charts of the endocrine and pituitary glands, as well as a bibliography with references to original journal studies make this a good pick for students entering the field of neuroscience, as well as scientists in other fields who are seeking to learn more. But laypeople who want to understand how stress affects the brain may be better off with Bill Moyers's less scientific but much more readable Healing and the Mind.
Copyright 2002 Reed Business Information, Inc.
From Library Journal
The stress response, paradoxically, can both ensure our immediate survival and threaten long-term physical and mental well-being. These titles describe the mechanisms involved in responding to stress, but they take different tacks. Bremner (psychiatry and radiology, Emory Univ. Sch. of Medicine) focuses on traumatic stress-its effects on individuals and their ability to work and to relate to others. His premise is that "stress-induced brain damage underlies and is responsible for the development of a spectrum of trauma-related psychiatric disorders." Bremner offers a persuasive argument for revising the current diagnostic schema of the Diagnostic and Statistical Manual IV (which currently classifies numerous trauma as distinct conditions) to provide for one single spectrum of disorders, including both acute and chronic posttraumatic stress disorder and related conditions. Like McEwen, Bremner details the biological mechanisms of the stress response, focusing especially on the changes that occur within the brain. The author also touches briefly on Freudian psychotherapy, the use of medical scanning devices, the nature vs. nurture argument, the validity of delayed recall, etc. Despite some occasional repetitive and awkward constructions in his text, Bremner offers an interesting and valuable perspective on the subject of traumatic stress. His book will particularly interest professionals. McEwen (head, Neuroendocrinology Laboratory, Rockefeller Univ.) uses the term allostasis to denote the stress response in which maximum energy is delivered to those parts of the body that will be critical for self-protection. Allostatic load, on the other hand, describes a system that turns against itself. McEwen discusses in detail the processes by which stress affects the cardiovascular and immune systems as well as the brain. The brain, according to McEwen, can be "the target as well as the initiator of the stress response." This system, however, need not inevitably threaten us. Lifestyle changes, including proper diet, exercise, rest, and the development of positive coping skills, can make an enormous difference in our ability to minimize the effects of chronic stress. McEwen's book is skillfully written and will appeal to a wide readership.
Laurie Bartolini, Illinois State Lib., Springfield Copyright 2002 Reed Business Information, Inc.
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