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This volume is the result of a workshop, sponsored by the National Cancer Institute in March 1990, which explored the epidemiology of multiple myeloma. The papers included in this volume address differences in immunologic factors and in risk factors for multiple myeloma between blacks and whites, describe the monoclonal gammopathies and their progression to myeloma, and speculate on hypotheses regarding the etiology and pathogenesis of this challenging malignancy. Questions that are addressed include whether neoplastic change occurs at the level of the plasma cell or earlier in the B-cell lineage, the role of inappropriate gene expression, the importance of IL-6 production, and new findings regarding the cytogenetics of this malignancy. Key directions for new research on multiple myeloma and related malignancies are also suggested.
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4
books
cite this book:
- Textbook of Malignant Haematology by Laurent Degos on page 601, and page 607
- Cancer Epidemiology and Prevention by David Schottenfeld on page 969
- Williams Hematology, 6th Edition by Ernest Beutler M.D. on page 1228
- The Genetic Basis of Common Diseases (Oxford Monographs on Medical Genetics, 44) by Richard A. King on page 771
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