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Written by international specialists, this volume describes recent advances in the study of chronic lymphocytic and hairy cell leukemia. Hairy Cell and Chronic Lymphocytic Leukemia: Thirty Years of Progress is based on the proceedings of the recent Rundles Symposium on Hairy Cell Leukemia and Chronic Lymphocytic Leukemia held at Searle Center of the Duke University Medical Center in Durham, North Carolina. Included in this volume are the latest developments in the study of chronic lymphocytic leukemia such as new information regarding its cellular origin, the immunologic aberrations caused by these abnormal lymphocytes, and the clinical manifestations of this disorder. This book also features progress in the study of hairy cell leukemia. Contributors to this volume describe the immunologic means of study and the use of gene probes for cells of B lineage that have led to today's clearer definition of the pathognomonic hairy cells. Also discussed is the recent and successful use of alpha interferon or 2-deoxycoformycin in the treatment of hairy cell leukemia.
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