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Handbook of Cryo-Preparation Methods for Electron Microscopy (Methods in Visualization)
 
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Handbook of Cryo-Preparation Methods for Electron Microscopy (Methods in Visualization) (Hardcover)

by Annie Cavalier (Editor), Daniele Spehner (Editor), Bruno M. Humbel (Editor)
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Customers buy this book with Introduction to Electron Microscopy for Biologists, Volume 88: Methods in Cell Biology by Terry D. Allen

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Product Description
The last two decades have seen exponential growth in cryo-electron microscopy, resulting in exciting advances, new hypotheses, and a better understanding of the ultrastructure of living and inert matter. Using an accessible, step-by-step format, this handbook presents the most sophisticated methods used in research laboratories. It describes the basic principles of cryo-fixation, cryo-ultramicrotomy, embedding at low temperatures and freeze-fracture. The book also explores applications such as electron crystallography, 2D/3D structure analysis, cryo-electron tomography, and techniques for protein localization. Each chapter covers a specific method, including detailed protocols, summary tables, and hundreds of illustrations and diagrams to clarify the techniques.

About the Author
University de Rennes, Rennes, Cedex, France University of Strasbourg, Illkirch, France Utrecht University, Netherlands

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