Studies heralding breakthroughs in investigational cancer regimens seem to erupt in the news media almost daily. Consequently, patients clamor for information about the reported trial results but remain largely unaware of the studies' overall operations, objectives, or intended outcomes. Medical journalist Finn does an outstanding job of detailing and demystifying the structure, administration, and history of various experimental cancer studies as well as the laws affecting them. In addition to providing a wealth of understandable background information, he gives the consumer step-by-step guidance for locating and appraising a clinical trial, intelligently and compassionately explores the pros and cons of whether to enter a research study, and writes superbly about what an informed consent document is and how to read one. All in all, Finn offers a thorough, thoughtful, and well-balanced look at an important topic not covered elsewhere. Recommended for public library and consumer health collections.AGail Hendler, Memorial Sloan Kettering Cancer Ctr. Lib., New York
Copyright 1999 Reed Business Information, Inc.
Product Description
For a very few cancers, treatment options are minimally invasive, resoundingly curative, and have very few side effects. However, most cancer patients face treatment options that are less than ideal. The odds they have been given for a chance of recurrence might be frightening. Or, the "cure rate" of treatment might be good, but the side effects (short- or long-term) might be daunting. However, there's great hope on the horizon. Basic research on cell biology is finally yielding important clues about the nature of cancer, and these clues are leading directly to promising new treatments. Physicians are finding better ways to alleviate cancer pain and some of the toxic side effects of chemotherapy. Medical device companies are testing new ways to detect cancer in ever earlier stages. And researchers are even developing therapies that will prevent the development of cancer in people who are at risk. Author Robert Finn, a science and medical journalist, believes that if you are not evaluating potential experimental treatments alongside the standard treatment protocols, you aren't considering all the facts you need. Cancer Clinical Trials is aimed at helping you consider the range of treatment options available through clinical trials -- treatments that may not be available any other way. It includes:
- Reasons to consider a trial (as well as reasons to decide against one)
- Structure of clinical trials and ethical guidelines
- Administration of trials (and what are the interests and involvement of players such as the FDA, pharmaceutical companies, the NCI, scientists)
- Inclusion and exclusion criteria for joining a trial
- Reading the trial protocol
- Hard questions to ask yourself and your doctor
- Interviews from researchers and patients
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