Review
"This elegant text addresses what is perhaps the most important conceptual development in late 20th-century neuropsychiatry. There is now common agreement that brain-behavior relationships are predictably tied to the organization of discrete yet interconnected neural circuits that link the frontal and limbic cortices with the basal ganglia. This volume explores the role of these 'loops' in the primary manifestations of specific lesion-based neurologic syndromes and then, by extension, in the expression of virtually every major class of neuropsychiatric disorder. Specific dysfunction of intricate neurochemical and synaptic subterritories within the frontal-subcortical circuits must account for conditions as categorically distinct as depression, schizophrenia, OCD, substance abuse, ADHD, mania, and Tourette syndrome. Extrapolating from the signature syndromes of frontal-subcortical circuit dysfunction to the complexities of such neuropsychiatric states will require a much finer parsing of these circuits. This text can serve as a valuable primer for this process--a road map to the circuit 'interstates' as we move ahead to explore the neuronal side streets of the psyche." --Neal R. Swerdlow, MD, PhD, Department of Psychiatry, School of Medicine, University of California, San Diego
"The arrival of this landmark volume could not be more timely. There is no other text available that devotes itself completely to the topic. Contributors cogently argue that a spectrum of neurological and psychiatric disorders should be placed within the context of a systems-level dysfunction. Lichter and Cummings have done a wonderful job of recruiting the leading proponents of the systems approach, and have masterfully integrated the chapters to reduce redundancy and enhance the integration of topics. This book is recommended for researchers in neuropsychiatry, behavioral neurology, and cognitive neuroscience, as well as practitioners in the clinical neurosciences who are yearning for a focused and intelligent alternative to simple localizationist views of behavior."--Jordan Grafman, PhD, Chief, Cognitive Neuroscience Section, National Institute of Neurological Disorders and Stroke
"This multiauthored volume...brings together in one place a succinct and well-written review of the current state of knowledge regarding frontal-subcortical circuits and their role in mediating normal neuropsychological function and neuropsychiatric disease. As such, this book may appeal to a broad spectrum of readers, including neurologists, psychiatrists, neuropsychologists, and researchers in neuroscience....this work fulfilled the promise of it editors to provide 'a comprehensive, integrated, state-of-the-art overview of the topic of frontal-subcortical circuits and their relevance to normal and disordered neurologic and psychiatric functioning.' ....a comprehensive course on the subject, yet the organization permits selective reading of specific topics of interest, and use of the remainder as a reference book."--Journal of the International Neuropsychological Society (JINS)
"Drs. Lichter and Cummins have compiled a series of chapters that, together, provide a relatively concise yet thorough overview of current knowledge about the nature and fuctions of the frontal-subcortical circuits....an outstanding volume that I strongly recommend to anyone interested in understanding brain functioning as it relates to neuropsychiatric disorders."--Journal of Clinical Psychiatry
"...provides a broad and rich foundation from which obsessive-compulsive disorder and other neuropsychiatric conditions can be approached with a better understanding of this relationship....The editors and contributors provide a valuable textbook that addresses the neuroanatomic and neurochemical basis of several important neurological and psychiatric conditions. The book should serve as an important resource for clinicians and researchers."--Psychiatric Services
"...recommended for physicians and others interested in providing health care to patients with neuropsychiatric disorders. The book is well written and has clear diagrams and multiple references. Its greatest value lies in the clear descriptions of the current basic neuroscience of the frontal-subcortical circuits."--The Journal of Nervous and Mental Disease
"This is a timely book devoted to the role of frontal-subcortical (FSC) circuits in various aspects of cognition, behavior, and physical functioning. The book is comprehensive: 16 chapters and more than 425 pages are devoted to cognate topics under the umbrella of FSC circuitry. In keeping with the principal interests and expertise of the editors, the book emphasizes psychiatric features associated with FSC circuits....The book has a number of strengths, beginning with the introduction and overview prepared by editors Lichter and Cummings. In fact, the introduction nicely summarizes most of the book's contents, and I recommend this chapter as required reading for all students of neuropsychiatry and behavioral neurology and perhaps even clinical neuropsychology....a book very much worth owning, if one has the occasion in the course of clinical practice to diagnose and manage cognitive and behavioral disorders related to FSC dysfunction. And in general, I don't doubt that many of the principal psychiatric disorders can be understood, to some extent, with reference to FSC circuits. This is a theme that Dr. Cummings has advanced for a number of years, in an eloquent and increasingly compelling fashion, and it is brought to center stage by this book."--Developmental Neuropsychology
Product Description
Contemporary research on the links between brain, mind, and human behavior has revealed the key role of the frontal-subcortical circuits in a wide range of neuropsychiatric syndromes and disorders. This authoritative volume reviews current knowledge on the anatomy of these circuits, their connections to other brain regions, and their influences on motor, cognitive, affective, and behavioral functioning. Specific clinical problems discussed include Parkinson's disease and other movement disorders, obsessive-compulsive disorder, ADHD, schizophrenia, and addictive disorders. Featured are a wealth of informative illustrations, with 8 pages in full color.
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