Epilepsy as a Dynamic Disease (Hardcover)

by John Milton (Editor), Peter Jung (Editor) "Temporal lobe epilepsy is not a static entity, but continuously evolves, and changes its character over the lifetime of the sufferer..." (more)
Key Phrases: brain defibrillator, epileptic system, epileptic foots, Are Cardiac, Morris Lecar, Hodgkin Huxley (more...)

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Product Description
A "brain defibrillator" may be closer than we think. An epileptic seizure involves a paroxysmal change in the activity of millions of neurons. Feedback control of seizures would require an implantable device that could predict seizure occurrence and then deliver a stimulus to abort it. To examine the feasibility of building such a device, this text brings together experts in epilepsy, bio-engineering, and dynamical systems theory. Topics include the development of epileptic systems, seizure prediction, neural synchronization, wave phenomena in excitable media, and the control of complex neural dynamics using brief electrical stimuli.

Product Details

• Hardcover: 420 pages
• Publisher: Springer; 1 edition (January 17, 2003)
• Language: English
• ISBN-10: 3540427627
• ISBN-13: 978-3540427629
• Product Dimensions: 9.3 x 6.2 x 0.7 inches
• Shipping Weight: 1.8 pounds (View shipping rates and policies)
• Average Customer Review: 5.0 out of 5 stars See all reviews (1 customer review)
• Amazon.com Sales Rank: #1,878,004 in Books (See Bestsellers in Books)

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5.0 out of 5 stars Epilepsy: Dynamic Models & Multicellular Processes, April 15, 2005

By	Joseph J Grenier "jjg MD PhD" (Aurora, IL United States) - See all my reviews (REAL NAME)

Milton and Jung's book is geared to the epileptologist, mathematical modelers, EEG personnel, the research scientist, and the neural engineer. This is not easily digested and understood. You have to read the book in sections to obtain the greatest insights. The book is better on theory and the physics of synchronization processes. The end of the book discusses the chance for a electrical defibrillator. We are presently at a very preliminary stage of development even though a vagal nerve stimulator has been found effective in certain refractory cases of uncontrolled seizures. This book firmly places Epilepsy as a dynamic illness with chaotic, often unpredictable characteristics and sets in motion ideas for a cortical integrated defibrillatory device. Let's hope we innovate and obtain one soon for clinical trials.