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Virus X: Tracking the New Killer Plagues--Out of the Present & Into the Future Hardcover – February 1, 1997

4.1 out of 5 stars 26 customer reviews

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Product Details

  • Hardcover: 448 pages
  • Publisher: Little, Brown and Company; 1st edition (February 1, 1997)
  • Language: English
  • ISBN-10: 0316763837
  • ISBN-13: 978-0316763837
  • Product Dimensions: 6.5 x 1.2 x 9.5 inches
  • Shipping Weight: 1.6 pounds
  • Average Customer Review: 4.1 out of 5 stars  See all reviews (26 customer reviews)
  • Amazon Best Sellers Rank: #5,627,324 in Books (See Top 100 in Books)

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Customer Reviews

Top Customer Reviews

By ealovitt HALL OF FAMETOP 100 REVIEWER on October 29, 2001
Format: Paperback Verified Purchase
For those of us who are nervous about the current anthrax outbreak, "Virus X" will not make very soothing bedtime reading. Dr. Ryan describes emerging plagues such as Ebola haemorrhagic fever, AIDS, and Junin fever in grim, gory, pathological detail. If that were not enough to keep his readers sleepless, the author spends the last few chapters theorizing on why new and perhaps deadlier plagues may soon emerge. In the final chapter, "Virus X - The Doomsday Scenario," he discusses the (thus far, theoretical) makeup of a virus that could cause the extinction of the human race.
Viruses already exist that are uniformly fatal to people, if not treated. Rabies is one of them, but luckily for us it has a rather clunky delivery system:
"The human rabies virus lives in a symbiotic cycle with bats, from which it is capable of infecting a wide variety of mammals, particularly foxes, coyotes, jackals, and rodents...The virus is programmed to infect the brain centers in the animal that induce uncontrollable rage, while also replicating in the salivary glands to best spread the contagion through the provoked frenzy of biting."
(The bad news is that out of the 5,000+ species of mammals on our planet, a thousand species are bats, and over two thousand species are rodents.)
Another almost uniformly fatal virus with a relatively inefficient delivery system is HIV-1.
Dr. Ryan asks the question, "Could such lethal agents [HIV-1, Ebola, rabies] ever take the second step, and become sufficiently contagious to infect all or virtually all of the human species?...the only route of contagion likely to prove universally threatening to humanity would be person-to-person spread by the respiratory route."
According to Dr.
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Format: Paperback
British science journalist and physician Frank Ryan covers a lot of ground in this extensively researched and engagingly written trek into the world of emerging viruses. These viruses, indigenous to disturbed areas of the world, particularly in the tropics, are now being sprung loose to threaten humankind.
The first third of the book covers the story of the "Four Corners" hantavirus that jumped from deer mice to humans with fatal effect in the southwestern United States in 1993. This is science journalism at its best.
In the next third of the book Ryan takes us to the jungles of Africa and traces the origin and effect of the horrendously brutal Ebola virus. Again he tells an engaging story with a pictorial vividness. One is amazed at the courage and dedication of the health care workers and medical scientists who risked their lives to treat the sick and dying and to find the source of the deadly disease.
At the beginning of the last third of the book, Ryan reprises what we know about HIV, its origins, its spread, the political and social stupidities involved in its spread, and the prospects for combating this terror. Again he makes the personalities and the nature of their work come to life. Then beginning with "Chapter Sixteen: The Aggressive Symbiont," Dr. Ryan discusses in general and theoretically the evolutionary nature of viruses, where they came from, why they exist and what we can expect from them in the future. Most pointedly he explores the possibility of a doomsday virus that is simultaneously as easily spread as influenza and as deadly as Ebola.
In a sense this part of the book, originally published in 1996, predicts the SARS outbreak, but does not stop there.
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Format: Paperback
As someone only peripherally involved with epidemiology and public health, I found Ryan's book an entirely fascinating read, and nowhere near as sensationalist as the title might have implied. Not only for its suspenseful chronology of how the courage and tenacity of epi researchers has us closer to understanding these natural threats, but also for the countless "aha" moments it offers on how viruses actually live and work.
Ryan strikes a good balance between readability and credibility, using both layman's terms and (as far as I can tell with the help of the MD/epidemiologist in the family) accurate use of the appropriate lingo for his subject matter.
Basing his narrative on actual outbreaks of different types has helped Ryan create easily accessible self-contained sections that make the book an easy bedsider.
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Format: Paperback
As a teacher who has a strange fascination with viruses, I use my summer to catch up on the latest books. While this book was in part a review of information presented in much more detail elsewhere (the endnotes are thorough with sources), the author's theory was new to me and kept me thinking for weeks. Even if you are quite familiar with the viruses discussed, I encourage you to read Dr. Ryan's conclusions.
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By A Customer on June 9, 1999
Format: Paperback
to the world of emerging infectious diseases, and epidemic research. However, much of the information he presents can be found in other books considered "MUSTS" in public health or epi bookcases, for example "The Coming Plague" by Laurie Garrett. If you're curious, or just want a comprehensive but general look into the world of emerging infectious diseases, this is the book for you.
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