See buying choices for this item to see if it's one of the millions that are eligible for Amazon Prime.

Casarett & Doull's Toxicology: The Basic Science of Poisons and over 300,000 other books are available for Amazon Kindle � Amazon�s new wireless reading device. Learn more

46 used & new from $11.00

See All Buying Options

Have one to sell? Sell yours here

Share with Friends

Share your own customer images

Search inside this book

Start reading Casarett & Doull's Toxicology: The Basic Science of Poisons on your Kindle in under a minute. Don�t have a Kindle? Get yours here.

Casarett & Doull's Toxicology: The Basic Science of Poisons (Hardcover)

by Curtis D. Klaassen (Author) "Toxicology has been defined as the study of the adverse effects of xenobiotics and thus is a borrowing science that has evolved from ancient poisoners..." (more)
Key Phrases: medullary proliferative lesions, thyroid follicular cell proliferation, high solubility ratio, New York, Toxicol Appl Pharmacol, United States (more...)

3.8 out of 5 stars See all reviews (12 customer reviews)

Available from these sellers.

16 new from $74.37 30 used from $11.00

Also Available in:	List Price:	Our Price:	Other Offers:
Kindle Edition (Kindle Book)		$74.84
Hardcover (7)	$120.00	$83.16	87 used & new from $71.02
Paperback (5th)			14 used & new from $28.98
Unknown Binding (2nd)			16 used & new from $4.05

There is a newer edition of this item:

Casarett & Doull's Toxicology: The Basic Science of Poisons (Casarett & Doull Toxicology) 3.8 out of 5 stars (12)
$83.16

In Stock.

What Do Customers Ultimately Buy After Viewing This Item?

	93% buy the item featured on this page: Casarett & Doull's Toxicology: The Basic Science of Poisons 3.8 out of 5 stars (12)
	3% buy Casarett & Doull's Essentials of Toxicology (Casarett and Doull's Essentials of Toxicology) 3.0 out of 5 stars (3) $47.84
	2% buy Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition 5.0 out of 5 stars (2) $68.20
	1% buy Principles and Methods of Toxicology, Fifth Edition 5.0 out of 5 stars (1) $146.20

Explore similar items

Customers Who Bought This Item Also Bought

Principles and Methods of Toxicology, Fifth Edition

by A. Wallace Hayes

5.0 out of 5 stars (1) $146.20

Goodman & Gilman's The Pharmacological Basis of Therapeutics (Goodman and Gilman's the Pharmacological Basis of Therapeutics)

by Laurence Brunton

3.8 out of 5 stars (10) $115.17

Casarett & Doull's Essentials of Toxicology (Casarett and Doull's Essentials of Toxicology)

by Curtis Klaassen

3.0 out of 5 stars (3) $47.84

Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition

by Urs A. Boelsterli

5.0 out of 5 stars (2) $68.20

Molecular Biology of the Cell

by Bruce Alberts

4.4 out of 5 stars (84) $115.09

› Explore similar items

Editorial Reviews

Review
"New figures and more focused highlights through the use of color makes this an exciting and almost fun-to-read text. "Once again this tome plowed new ground and sown it with authoritative, comprehensive, and well written compilation of what toxicology's all about and how it affects our world and its inhabitants." (Veterinary Human Toxicology )

"This book is now an established classic in the field of toxicology. In the time between the fifth and sixth edition, there have been significant advances in research that warrant this edition. When it comes to completeness, there really is no comparable book on the market. " (Doody's )

Product Description
Long-established as the gold standard in the field, Casarett and Doull's Toxicology is now available in a new Sixth Edition that equips you with an unsurpassed treatment of modern toxicology, including the principles, concepts, mechanisms, and modes of thought that are the foundation of the discipline.

Comprehensive and completely up to date, the new edition of Casarett and Doull's Toxicology remains your best source for the latest breakthroughs in this fast-changing field.
* The new edition of this gold standard in the field is more valuable than ever
* Detailed coverage of the advances in molecular biology and pharmacogenetics
* Expanded coverage of risk assessment
* Coverage of online references, in addition to traditional print journal and review articles
* New chapter outlines
* New 2-color design

See all Editorial Reviews

Product Details

Hardcover: 1275 pages
Publisher: McGraw-Hill Professional; 6 edition (July 27, 2001)
Language: English
ISBN-10: 0071347216
ISBN-13: 978-0071347211
Product Dimensions: 11 x 8.7 x 2 inches
Shipping Weight: 6.2 pounds

Average Customer Review: 3.8 out of 5 stars See all reviews (12 customer reviews)

Amazon.com Sales Rank: #406,404 in Books (See Bestsellers in Books)
Popular in this category: (What's this?)
#34 in Books > Professional & Technical > Medical > Administration & Medicine Economics > Public Health > Toxicology

Would you like to update product info or give feedback on images?

Inside This Book (learn more)

First Sentence:
Toxicology has been defined as the study of the adverse effects of xenobiotics and thus is a borrowing science that has evolved from ancient poisoners. Read the first page

Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
medullary proliferative lesions, thyroid follicular cell proliferation, high solubility ratio, plasma chemical concentration, underground mining cohorts, ecologic risk assessment, chromaffin cell proliferation, xenobiotic biotransforming enzymes, oxidative group transfer, skeletal dose, carbamate ester insecticides, progressor agents, aggregated detriment, bicyclic aromatic amines, effective promoting agents, human developmental toxicants, nephrotoxic acute renal failure, tubulostromal adenomas, analytic toxicology, ultimate toxicant, tumorigenic metabolites, cardiac myocyte death, parathyroid chief cells, developmental immunotoxicology, neurofilamentous swellings

Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Toxicol Appl Pharmacol, United States, Environ Health Perspect, Mutat Res, Cancer Res, Raven Press, Environmental Protection Agency, Fundam Appl Toxicol, Boca Raton, Pharmacol Exp Ther, Pergamon Press, Marcel Dekker, Toxicol Sci, Biol Chem, Ind Med, Academic Press, Arch Environ Health, Comprehensive Toxicology, Crit Rev Toxicol, Proc Natl Acad Sci, Toxicol Environ Health, Toxicol Lett, Toxicol Pathol, Arch Toxicol

New!
Books on Related Topics | Concordance | Text Stats

Citations (learn more)

This book cites 96 books:

Toxic Substances Control Act: Compliance/Enforcement Guidance Manual by Environmental Protection Agency on 8 pages
Federal Insecticide, Fungicide, and Rodenticide Act: Compliance/Enforcement Guidance Manual by U S Environmental Protection Agency St on 4 pages
Ecological Risk Assessment: Federal Guidelines by U.S. Environmental Protection Agency on page 1043, page 1044, and page 1045
Risk Assessment in the Federal Government: Managing the Process by Committee on the Institutional Means for Assessment of Risks to Public Health on page 83, page 349, and page 1011
Clean Air Act: Compliance/Enforcement Guidance Manual : Policy Compendium by Environmental Protection Act on page 12, page 980, and page 1152

See all 96 books this book cites

9 books cite this book:

Risk and Reason: Safety, Law, and the Environment by Cass R. Sunstein on page 170, Back Matter (1), and Back Matter (2)
Risk and Reason: Safety, Law, and the Environment by Cass R. Sunstein on page 170, Back Matter (1), and Back Matter (2)
Calculated Risks: Understanding the Toxicity of Chemicals in our Environment by Joseph V. Rodricks in Back Matter (1), and Back Matter (2)
Practical Occupational Medicine by Anthony Seaton in Back Matter
Principles and Methods of Toxicology by A Wallace Hayes on page 1185

See all 9 books citing this book

Books on Related Topics (learn more)

Principles and Methods of Toxicology by A Wallace Hayes

Discusses:

Goldfrank's Toxicologic Emergencies by Lewis Goldfrank

Discusses:

Maxcy-Rosenau-Last Public Health & Preventive Medicine by Robert B. Wallace

Discusses:

Experimental and Clinical Neurotoxicology by Peter S. Spencer

Discusses:

Tags Customers Associate with This Product

(What's this?)

Click on a tag to find related items, discussions, and people.

toxicology(2)

environmental science(1)

See all 4 tags...

Help others find this product — tag it for Amazon search

No one has tagged this product for Amazon search yet. Why not be the first to suggest a search for which it should appear?

Customer Reviews

12 Reviews

5 star:		(7)
4 star:		(1)
3 star:		(1)
2 star:		(1)
1 star:		(2)

Average Customer Review

3.8 out of 5 stars (12 customer reviews)

Share your thoughts with other customers:

Create your own review

Most Helpful Customer Reviews

12 of 12 people found the following review helpful:

3.0 out of 5 stars 7th Edition, Essential if Flawed, January 1, 2008

By	W. David McGuinn Jr. (Columbia, MD USA) - See all my reviews (REAL NAME)

This review is from: Casarett & Doull's Toxicology: The Basic Science of Poisons (Casarett & Doull Toxicology) (Hardcover)

This is a book by and for professional toxicologists. Folks in the field have long regarded it as the standard. It is the primary text for most graduate programs in toxicology around the world. I own editions 2, 4 and now 7. Despite some of the rather uninformed reviews below, it does keep getting better with each subsequent edition. And note the dates on some of the other reviews, they refer to earlier editions. Number 7 just came out in November.

I cannot compare the 7th edition to number 6 but I can say that relative to number 4 the introductory chapters are much improved. The first three chapters provide a solid overview of the History of Toxicology, Principles of Toxicology and Mechanisms in Toxicology. The only thing missing here is a chapter similar to Shan Gad's excellent treatise on Statistics in Toxicology found in A. W. Hayes' "Principles and Methods of Toxicology" (which you should also own). Andrew Parkinson's chapter, Biotransformation of Xenobiotics, is by itself worth the purchase price, and the chapter on Toxicokinetics is one of the best short discussions of this subject I have seen. The book then has chapters on Chemical Carcinogenesis, Developmental Toxicology and toxicology related to various organ systems. As with any large text written by a group of experts in a particular field these chapters are variable in quality and sometimes tend to emphasize the research interests of the individuals writing the chapter. I found the chapter on hepatic toxicology terse and inadequate considering the importance of this organ system. The chapters on pulmonary and renal toxicology are stronger. With the exception of the chapter on metals, the other chapters on Toxic Agents are far from comprehensive. The topics of animal venoms, plant toxins, radiation and pesticides really require books of their own but the treatment here is adequate for the entry-level graduate student. The chapter on Regulatory Toxicology is most informative if about as exciting as watching paint peel.

The book does contain a very few factual errors, but this is not surprising in a book this size written by so many people. It does not make the book any less valuable for the toxicologist. It would be next to impossible for Dr. Klaassen to police completely such a massive text. That said, the editing (and certainly the printing) has not yet approached the level of sophistication found in such texts as Goodman and Gilman or Harrison's Principles of Internal Medicine. The book still cries for greater internal consistency and the imposition of standards that lead the individual chapter authors away from their personal interests (I had an advisor once that taught four lectures to medical students on cyanide, he was the expert) and more toward general principles and practice. There is also a glaring lack of information about the now not so new advances in molecular toxicology; some of the authors need a few new arrows in their quivers. But, the single worst fault of the book is the index or serious brevity there of. For example, the chapter on ocular toxicology describes the classic Draize test over nearly two pages yet the word Draize is nowhere to be found in the index. It lists very few chemicals. This lack of a comprehensive index seriously limits the usefulness of the book as a reference. You already have to know a lot of toxicology to find what you are looking for in the text.

If you aspire to be a toxicologist (and you should), buy this book. If you desire to become a Diplomate of the American Board of Toxicology (and you should), buy this book - many of the exam questions come directly from it. Once you really know enough to understand its flaws you will probably be a toxicologist.

Comment Comments (2) | Permalink | Was this review helpful to you? Yes No (Report this)

11 of 12 people found the following review helpful:

5.0 out of 5 stars A very complete book about biomedical/environmental tox, February 19, 2004

By	Mike_brazil "Michael" (Belo Horizonte, MG, Brazil) - See all my reviews

Mr. Klassen did a very good job with the sixth edition of the classical Casarett and Doull`s. This is not a book for people scared of details, complex subjects and very long chapters. The book is not what I would call an easy read but I don't think that it should be anyway. Chapters cover diverse topics in a very complete manner, and as another reviewer said this is a book intended for advanced undergraduate courses or graduate toxicology courses. Only buy this book (which by the way is pretty expensive) if you intend to do research or work directly with toxicology. One final note, this is not a book oriented for the clinical setting. If you are a MD or health professional intending to use a book in the toxicological ER you should buy Goldfrank's Toxicologic Emergencies (which is a great book by the way).

Comment Comment | Permalink | Was this review helpful to you? Yes No (Report this)

14 of 16 people found the following review helpful:

5.0 out of 5 stars If you can only buy 1 toxicology reference, make it this one, August 24, 2004

By	R. Cattolica "PhD student" (CA USA) - See all my reviews (REAL NAME)

I found this to be an outstanding and thorough treatment of the entire gamut of toxicology. The book is well organized, with a very logical sequence of chapters. Each chapter is authored by recognized experts in the various subspecialties of toxicology, such as neurotoxicology. The principles and model systems of each specialty are discussed in detail. This text contains no fluff. I recommend it for graduate level students and above, though ambitious undergraduates may find it useful as well. My only suggestions for improvement would be updated figures and a glossary of terms. I sometimes found that authors of the earlier chapters would use terms which were not defined until later chapters. Overall, this is an excellent reference--well worth the price.

Comment Comment | Permalink | Was this review helpful to you? Yes No (Report this)

Share your thoughts with other customers: Create your own review

› See all 12 customer reviews...

Most Recent Customer Reviews

4.0 out of 5 stars 'The basic science...' is more science than most will need!
This seventh edition of 'Casarett & Doull's Toxicology: the Basic Science of Poisons' is a solid piece of science work. It is comprehensive, and broad at the same time. Read more

Published 5 months ago by Paul Almond

5.0 out of 5 stars not enough detail
the book is huge, and lots of topics. it is supposed to be a toxicology standard. however, the authors act afraid to go into any detail. try to find a better book. Read more

Published 6 months ago by G. Cates

5.0 out of 5 stars Great book!!! totally worth it
I feel this is a great book for toxicology students. I am a PhD student and I find it very very useful.......I am not sure about undergrads. I totally liked it.

Published 9 months ago by S. Kumbar

5.0 out of 5 stars it's still the ultimate toxicology book
there is not that much to say, really. Casarett & Doull's Tox book has been THE toxicology textbook for the past years. Read more

Published 22 months ago by Peko

1.0 out of 5 stars Hopeless
As a doctoral graduate in toxicology and now a practicing preclinical toxicologist for several years, I rate this book not only as "poor", but poorer with each new edition... Read more

Published on June 12, 2007 by derek141

2.0 out of 5 stars errors in the book
That is a good book for the beginner of toxicologist. However, many existed errors may mislead and confuse the beginners. So I recommend that we'd wait for next edition.

Published on April 26, 2004 by ping zhou

1.0 out of 5 stars Many errors
That is a really good book for the beginer of toxicologist. However, there are many errors existed and those errors could mislead and confuse the beginer. Read more

Published on April 26, 2004 by ping zhou

5.0 out of 5 stars TECHNICALLY CORRECT
This is a must have for the studying ENVIRONMENTAL ANALYST who is determined to KNOW HIS/HER HOMEWORK! Read more

Published on January 31, 2002 by la_chameleon

5.0 out of 5 stars I only can say....
WOW !!! what a book. If you are a pest control professional. BUY THIS BOOK. If you are a food industry professional, BUY THIS BOOK, If you are an ecologist, BUY THIS BOOK. Read more

Published on July 6, 2001 by H. Pons

› See all 12 customer reviews...

.jsOffDisplayBlock { display: block; } .jsOffDisplayInline { display: inline; } .jsOffVisibility { visibility: visible; } .jsOnDisplayBlock { display: none; } .jsOnDisplayNoneBlock { display: block; } .jsOnDisplayNoneInline { display: inline; } .jsOnDisplayInline { display: none; } .jsOnVisibility { visibility: hidden; } .jsOnDisplayBlock { display: none; } .jsOnDisplayInline { display: none; } .jsOnVisibility { visibility: hidden; }

Customer Discussions

Beta (What's this?)

New! See all customer communities, and bookmark your communities to keep track of them.

This product's forum (0 discussions)

	Discussion	Replies	Latest Post
	No discussions yet

Ask questions, Share opinions, Gain insight

Start a new discussion

Topic:

First post:

Receive e-mail when new posts are made

Prompts for sign-in

[Cancel]

Guidelines

Active discussions in related forums

Discussion	Replies	Latest Post
textbook Textbooks for Kindle DX?	40	3 days ago
textbook Does anyone use Discovering Geometry: An Investigative Approach?	5	3 days ago
medicine Medical Care in the United States	46	5 days ago
medicine Medicine's Mystery	4	6 days ago