Going on PC here with quad 3.0, wired 360 controller, 4GB RAM, and 550TI on Win7 64(easily enough to bounce the recommendeds), so keep this in mind.
Story so far is great from what I've seen so far. Controls are fluid and responsive for what you are asking for. I would have liked to have been able to turn off the QTE's(whoever thought that making someone quickly toggle the left analog back and forth was a good idea needs to have their head examined by my knee), but once you get out of the starting area, they become much less of an issue.
It has been super easy to grind up some skill points as hunting not only gives you xp, but you get many, if not all, of your arrows back.
I've only experienced 2 negatives to this point, but one of them is a doozy. I keep getting CTD's every 10-15 minutes or so. After playing around with some settings, I went to the forums and discovered that I'm not the only one experiencing these. I expect a patch to release shortly, and the autosave option does a decent job of preventing me from having to play too much over again. That leads me to the second negative; the lack of a manual save. While the autosave does seem to do an ok job to this point, I hate to rely on that.
Even with the CTD's, I'm loving it. That really should say something. The story picks up quickly, and doesn't really slow down.
I'm giving it a 7.4 at this point because of the issues with PC. I firmly expect for a patch to be coming to alleviate those issues and it will be a very shiny experience after that.