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Bioinformatics For Dummies [Paperback]

Jean-Michel Claverie Ph. D. (Author), Cedric Notredame Ph.D. (Author)
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Editorial Reviews

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“…buy soon and read fast!…” (Spixiana, July 2004)

"...will be of enormous practical assistance to anyone getting to grips with bioinformatics tools in the course of their research..." (Briefings in Bioinformatics, June 2003) --This text refers to an out of print or unavailable edition of this title.

Product Description

Were you always curious about biology but were afraid to sit through long hours of dense reading? Did you like the subject when you were in high school but had other plans after you graduated? Now you can explore the human genome and analyze DNA without ever leaving your desktop!

Bioinformatics For Dummies is packed with valuable information that introduces you to this exciting new discipline. This easy-to-follow guide leads you step by step through every bioinformatics task that can be done over the Internet. Forget long equations, computer-geek gibberish, and installing bulky programs that slow down your computer. You’ll be amazed at all the things you can accomplish just by logging on and following these trusty directions. You get the tools you need to:

  • Analyze all types of sequences
  • Use all types of databases
  • Work with DNA and protein sequences
  • Conduct similarity searches
  • Build a multiple sequence alignment
  • Edit and publish alignments
  • Visualize protein 3-D structures
  • Construct phylogenetic trees

This up-to-date second edition includes newly created and popular databases and Internet programs as well as multiple new genomes. It provides tips for using servers and places to seek resources to find out about what’s going on in the bioinformatics world. Bioinformatics For Dummies will show you how to get the most out of your PC and the right Web tools so you’ll be searching databases and analyzing sequences like a pro!

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Product Details

  • Paperback: 456 pages
  • Publisher: For Dummies; 2 edition (December 18, 2006)
  • Language: English
  • ISBN-10: 0470089857
  • ISBN-13: 978-0470089859
  • Product Dimensions: 9.1 x 7.2 x 1.1 inches
  • Shipping Weight: 1.3 pounds (View shipping rates and policies)
  • Average Customer Review: 4.6 out of 5 stars  See all reviews (18 customer reviews)

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More About the Author

Jean-Michel Claverie
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
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Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
bootstrap alignment, paste your sequence, tcof fee, sequence input box, use blastp, human parvalbumin, dummy alignment, ple sequence alignment, conserved columns, big alignments, bottom cursor, following steps list, save your results, intermediate page, multiple alignment, dot plot, sequence window, query sequence, sequence format, conserved positions, percent identity
Key Phrases - Capitalized Phrases (CAPs): (learn more)
File Edit View Favorites Tools Help, Address Description, Motif Scan, Neighbor Joining, Internet Explorer, Pasteur Institute, European Bioinformatics Institute, Site Map Search, Amos Bairoch, European Molecular Biology Laboratory, Microsoft Word, Choose Swiss-Prot, Entrez Gene, Press the Submit, Protein Information Resource, Select the Text, Survival Guide, Wave By Rich Tennant, World Wide Web
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Customer Reviews

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4.6 out of 5 stars (18 customer reviews)
 
 
 
 
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30 of 34 people found the following review helpful:
5.0 out of 5 stars A great resource for teachers too!, June 24, 2003
By "ndrewtan" (Singapore) - See all my reviews
This review is from: Bioinformatics for Dummies (Paperback)
I have used databases before (mostly NCBI, TIGR and SWISS PROT) and yet, this book (presumably for dummies) has shown me so much more(which say a lot about me)! It is accurate and gives good step by step guide to how to perform many tasks - from how to find a gene to using the analysis tools and to exploring some of the newer features of these databases - and the areas like you have never looked into before.
It is a well-researched book and the authors are clearly knowledgeable in this area.

Even though I have been for a 4-day bioinformatics course (6 months ago), which I thought was pretty good, this book still had so much to offer. Using this book, I was easily able to substitute the proteins of my interest into their examples and generated meaningful hits.

The book also covers deeper and more advanced features of BLAST, discusses sequence alignments using several types of algorithm and even has a section on 3D structures. Towards the end of book - it features a section on working with mRNA and building phylogenetics trees - which again are excellent resources for teachers involved in teaching beginners molecular biology.

I am a teacher teaching at a Pre-unversity level. The way the book is structured also lends its material to be modified into lesson materials for training students.

It is really a great book! Worth every dollar I spent on it!

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33 of 39 people found the following review helpful:
5.0 out of 5 stars Bioinformatics for Dummies by J.M. Claverie & C. Notredame, January 14, 2004
By Tamsen De Valoir "tvaloir" (Alvin, TX United States) - See all my reviews
(REAL NAME)   
This review is from: Bioinformatics for Dummies (Paperback)
"Bioinformatics for Dummies" is an excellent resource. It is clear, easy to read, well organized and illustrated. I was particularly pleased by the colloquial tone of the writing: in addition to being informative, it was fun to read!

As a scientist who spends at least half of my time BLASTing, I also read it for accuracy and found it to almost error-free (any errors were in the figures). Additionally, most of the web pages were up-to-date, although as time passes the links will decay and web pages will change their look. In addition, the book contained enough in-depth content to teach me several new tricks of the trade.

Further, I believe the book had sufficient background material to educate the novice. To test this, I gave the manual to a material science chemist and he was able to understand the material, at least until he decided it was more than he wanted to know and quit reading.

This is a useful text for those who want to know more than an operational definition of bioinformatics and a must for the library of all bioinformatics users.

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68 of 84 people found the following review helpful:
3.0 out of 5 stars disappointing from the viewpoint of a computer scientist..., March 19, 2005
This review is from: Bioinformatics for Dummies (Paperback)
I hold a masters degree in computer sciences (so in fact I am a biology dummy), but always had a strong interest for sciences. So I want to delve deeply into this fascinating area, but first wanted to read a book to quickly introduce me the basic concepts. With this background, I must say the book is a little bit disappointing. You can clearly see that this book is written with the biologist in mind, definitely not the computer scientist.
The biological concepts are not explained very well for a biology dummy, let me explain you why :
1. Some basic biological concepts are not explained. I wanted to have some more explanation on the basic concepts of how molecular and cell biology works. A lot of times, the autors tell you how to use some tool, but is not always clearly explained to me why, for what purpose they use the tool. For instance they explain how to find a list of related protein sequences, but for me it is not clear why biologists need to have such a list. And this is only one example, I could give much more simular examples...
2. Remember guys, I am a dummy, so please explain me the difference between a gene and a genome before using these terms. And also, I heard about chromosomes, but why do you not explain what is it exactly ?. Also, there are a lot of explanations on how to work with RNA, but please explain me more about the functional difference between RNA and DNA.
3. The explanations on how to use serveral internet tools are too wordy, they spent several pages explaining things that are so intuitively clear like "click this or that button", "use menu file, edit, copy to past your stuff to the computer clipboard"....
4. A lot of complex terms are or not explained the first time they use it ("phylogenic"). Sometimes these terms are explained further in the book, but from a didactical standpoint, you should at least give an informal definition when you first use some concepts...

Conclusion: I currently read the first hundred pages of the book and maybe I will change this review later on. But I can already tell : the first chapters might be well suited for a computer dummy, but definitely not for a biology dummy. However with some help of the internet(for instance there is an excellent explanation on how cells work at the howstuffworks website http://science.howstuffworks.com/cell.htm), I will continue to read the book further. Maybe after that I will need to change my preview...

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Most Recent Customer Reviews

5.0 out of 5 stars A great start!
Very simple and very well explained, I recommend this book to all who show interest in using bioinformatics as a research tool.
Published 17 months ago by Alexander Brown

4.0 out of 5 stars great reference
As a Phd student in biology, this book offers great reference for bioinformatics in a clear and smooth manner. Read more
Published 19 months ago by R. Doueiri

4.0 out of 5 stars Good Purchase
Good concepts for a beginner ad intermediate level. Concepts are clearly explained and are easy to understand.
Published 22 months ago by Anup Singh

4.0 out of 5 stars Overall a Good Book on Bioinformatics
This is overall a good book on bioinformatics. If you like the Dummy series, you will like this book. Read more
Published 23 months ago by Maxim

5.0 out of 5 stars Thorough, in-depth introduction. The "for dummies" is misleading
Many people are derisive about the "for Dummies" series, believing them to be too simplistic and sometimes even an insult to their intelligence. Read more
Published on August 6, 2008 by Charles Ashbacher

4.0 out of 5 stars Using the free software on internet sites to help your research
The first chapter is a short review of DNA and RNA sequences, amino acids, and protein. The other chapters teach you to use the free software found on the Internet to work with... Read more
Published on March 13, 2007 by Marcelo Frangetto

5.0 out of 5 stars Good
I am a couple years into a PhD in bioinformatics, but this is the book I started with. I knew some biology and some computer science, but I still found a lot of the databases,... Read more
Published on February 15, 2007 by Solanum

5.0 out of 5 stars Yes, It's Really Written at the For Dummies Level.
This book kind of blew me away. Bioinformatics is such a big word.

Then in the second chapter they tell you 'How Most People Use Bioinformatics. Read more
Published on January 17, 2007 by John Matlock

5.0 out of 5 stars Great introductory text
This is an excellent introduction to Bioinformatics. It does assume some very basic knowledge of biology- perhaps a couple of paragraphs could help the total newbies... Read more
Published on September 19, 2006 by Martin Gollery

5.0 out of 5 stars great beginner
In spite of the title (I don't know many dummies interested in multiple sequence alignments) this reference is written by experts in the field of bioinformatics and is very... Read more
Published on December 15, 2005 by J. M. Ridlon

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