No you cannot. I am typing your answer with this keyboard connected to my Samsung TV right now. It works great in the web browser, but will not operate to search in any Samsung Apps. I even looked at getting the Samsung wireless keyboard and even it does not work in the apps.
Yes you can do searches but for some reason the wireless keyboard does not function when I attempt to use it for Netflix. Only the Samsumg remote seems to work in conjunction with the on screen keypad.
Here is what I found out from Samsung about an es6150
"Does your Logitech work with any other applications? Currently, no keyboard is compatible with the YouTube and Netflix applications. This is because Netflix and YouTube did not add the functionality when they were programming these applications. Even if you were to purchase our $100 wireless keyboard, it would still not be able to operate Netflix and YouTube. I also do not have a list of keyboards that can work. I have been told that most Logitech keyboards will work with the television, and I hope that yours is working aside from these applications. "
I'm not sure. If the your Smart TV allows you to connect a Bluetooth device to it then it may work but I haven't had the opportunity to experiment at all with any of the Smart TV's to give you a solid answer. Sorry, that I was not able to clear that up for you.