Having read and reviewed the book a year ago, and even liked parts of it, I think what turns so many people off, and should be taken more seriously is the plethora of books by Americans that are so self absorbed.
Its rare to read books in Europe, Asia etc., by authors who are so self absorbed and living extremely well off material lives. Who then run around the world trying to find themselves.
Heck many if not most Americans don't do this. Instead they discover themselves by helping others in their communities.
Many a therapist will suggest if you are depressed because of a situation that you stop dwelling on you and start doing for someone else. That and change your diet and get rid of the junk. You don't have to run away as the author did, to find what matters.