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In-vitro Toxicity Testing
 
 
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In-vitro Toxicity Testing [Hardcover]

J. M. Frazier (Author)

Price: $189.95 & this item ships for FREE with Super Saver Shipping. Details
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Book Description

January 31, 1992 0824786149 978-0824786144 1
This volume focuses on the potential application of in vitro procedures to identify and quantify the toxicological risk to target organs associated with the use of commerical products and therapeutic drugs.;Revealing how the results of in vitro toxicity testing can be used in safety assessment, In Vitro Toxicity Testing: explores whether existing test methods can accomplish the necessary goals and, if not, what research is needed to make these techniques a practical reality; presents the current status of toxicity testing in the areas of hepatotoxicity, renal toxicity, ocular irritation, and many others; outlines the role of validation in technology transfer from the research laboratory to safety evaluation; examines testing strategies and regulatory acceptance and addresses common concerns about the ultimate utilization of available methods in chemical safety/hazard considerations; and analyzes the perspective of industrial and regulatory agencies on the application of in vitro toxicity testing.;Generously referenced with over 1400 literature citations, In Vitro Toxicity Testing is for academic, industrial, and regulatory toxicologists; applied, molecular, and cell biologists; pharmacologists; animal welfare activists; and graduate students in pharmacology and toxicology courses.

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Inside This Book (learn more)
First Sentence:
The objective of toxicity testing is to develop an adequate database to make reasonable and reliable judgments concerning the safe use of chemicals for societal needs. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
vitro toxicity testing systems, ocular safety assessment process, ocular safety testing, radiolabel release, ocular safety assessments, renal cell lines, vitro toxicity tests, silicon microphysiometer, immunoallergic hepatitis, adult human hepatocytes, vitro toxicology, irritancy potential, whole animal testing, hepatocyte lines, embryo culture system, renal slices, reaggregate cultures, isolated proximal tubules, ocular irritancy, mutagenicity data, irritation testing, teratogenicity test, toxicological process, product safety evaluation, eye irritation potential
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Mary Ann Liebert, Food Chem, Cell Biol, Les Editions, Brain Res, John Libbey Eurotext, New Directions, Ocular Toxicol, Raven Press, Teratogenesis Carcinog, Chemical Bank, Life Sci, Marcel Dekker, Academic Press, Cancer Res, Cell Res, Environmental Protection Agency, United States, Cancer Lett, Drug Metab, Health Perspect, New Jersey, Investigator Selected, Kidney Int, National Toxicology Program
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