I'm not familiar with the Innotab, except for what I just lookes up. It says it can use SD or SDHC cards up to 32GB. This card has worked for me in several cameras and I can't see why you should have any trouble unless the innotab 2s has issues. I've used Transcend products for a long (don't ask how long!) time with no trouble at all. Good luck!
I am very sorry that i cannot help you im not a tech freak i usually get lost and have to ask my boyfriend or son for help.. i purchased this for a digital camera nd it does work! very sorry i could nt help! :(