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K9 Advantix II Flea and Tick Control Treatment for Dogs

4.2 out of 5 stars 3,455 customer reviews
| 110 answered questions

List Price: $87.36
Price: $55.33 & FREE Shipping. Details
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Ships from and sold by Amazon.com.
Over 55 Pound
6-Month
  • Kills adult fleas, eggs and larvae
  • Remains effective even after swimming or shampooing
  • One treatment prevents further flea infestation for at least four weeks
  • Packaging may vary
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Frequently Bought Together

  • K9 Advantix II, Extra Large Dogs, Over 55-Pound, 6-Month
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Total price: $108.32
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Product Description

Size: Over 55 Pound | Style: 6-Month

Kills adult fleas, eggs and larvae. Biting fleas are more than just a nuisance for your dog. Left unchecked, they can cause serious disorders such as flea allergy dermatitis, secondary skin infections, tapeworms, and even anemia. This topical flea treatment lets you stop fleas before they become a problem. Used just once a month, it stops fleas from biting in less than five minutes, killing 98 to 100 percent of the fleas on dogs within 12 hours, and keeps working for a month. The dead fleas can't lay eggs, and the dead larvae can't hatch, breaking the flea's life cycle and halting the infestation in its tracks. A powerful solution, it also repels and kills ticks before they can attach and mosquitoes before they can bite. Applied before the start of flea season, it helps keep your dog from becoming infested in the first place. Used year-round, it prevents fleas from over-wintering in your home to feast on your dog next season. Gentle enough for puppies as young as seven weeks and older, the flea control remains effective even after bathing, water immersion, or exposure to sunlight, without the need for re-application. This package includes six pre-measured doses for dogs weighing 55+ pounds in easy-to-use applicator tubes. For safety, keep out of the reach of children, and read all warnings and instructions carefully.

Product Details

Size: Over 55 Pound | Style: 6-Month
  • Product Dimensions: 7.8 x 1 x 4.2 inches ; 1.6 ounces
  • Shipping Weight: 2.4 ounces (View shipping rates and policies)
  • Domestic Shipping: Item can be shipped within U.S.
  • International Shipping: This item is not eligible for international shipping. Learn More
  • ASIN: B004QRJJ0K
  • Item model number: 5461650
  • Average Customer Review: 4.2 out of 5 stars  See all reviews (3,455 customer reviews)
  • Amazon Best Sellers Rank: #51 in Pet Supplies (See Top 100 in Pet Supplies)
  • Manufacturer’s warranty can be requested from customer service. Click here to make a request to customer service.

Customer Questions & Answers

Customer Reviews

Top Customer Reviews

Style Name: 4-MonthSize: 11 to 20 Pound
I live in a heavily tick-infested area with a high rate of Lyme disease, so ticks are a major problem for my pup, especially because of the mild winter. Before using K9 Advantix II, I was using BioSpot (which works wonders for fleas). We went on a walk in the woods and over the course of the next four days, I picked 17 ticks off my dog! I was so grossed out, and she was miserable because I wouldn't leave her alone with the tweezers.

Initially, I tried a lot of home remedies, but nothing kept the ticks away. After picking more ticks off her, I decided to try another topical treatment. I did A LOT of research on which product to use, and I finally decided on K9 Advantix II. However, before I put it on her, I researched every ingredient in K9 Advantix II to rate its toxicity. In fact, I even read hazard sheets put out by federal and state agencies. All the CREDIBLE sources (i.e., scientific entities, not ranting pet owners) agreed that the ingredients are relatively safe WHEN USED APPROPRIATELY. This latter point is the key here...

I found that the ingredients in this flea medicine, as well as in others (e.g., Frontline, BioSpot), do not enter the bloodstream from the skin. However, if they are INGESTED, then you may have issues, including neurological effects and such. Most of these issues, according to my research, do go away after time, but we have heard enough horror stories to know that may or may not be true. You have to be particularly careful, though, because sometimes your dog many get dermatological effects (e.g., a rash) from this medicine, and his/her reaction will likely be to lick the spot to ease that discomfort.

Anyway, the lesson here is twofold: 1) Read the instructions on how to apply this medicine so your dog cannot lick the medicine off.
Read more ›
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Style Name: 6-MonthSize: Over 55 Pound Verified Purchase
I have been using Advantix for 14 years now and have found nothing better. Have compared it to cheaper store brands and to Frontline, but the Advantix works best. My outside dogs are not bothered by fleas, ticks or even flies. I have read some poor reviews on this product, but neither of my dogs have ever experienced any side effects to Advantix, even when they were young. It seems that when I used Frontline in the past, the directions said to put the entire contents of the tube in one spot between the shoulder blades, whereas Advantix specifically states to disperse in four areas from the shoulders to the base of the tail. I wonder if some people are putting all of it in one spot and that is causing irritation?
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Style Name: 4-MonthSize: 11 to 20 Pound
I had a flea infestation in my house and on my dog. I used Frontline, bombed the house, and have been vacuuming daily. I could see a few dead fleas that fell off my dog after the first 24 hours of Frontline and was waiting for more to die off but that wasn't the case. I followed the instructions exactly, but after the first 3.5 weeks the problem seemed to get worse. I was using Capstar in addition to kill off the adults, but it seemed they kept appearing! I read that Frontline has become less effective in the past few years and that seems to be true. I read some reviews on Advantix II and decided to try that for the second month. I know it takes three months to break a flea cycle but this seems to have worked after the first week! I gave him Advantix II and a Capstar the first day and I haven't seen a flea since. This stuff is AMAZING and my frustrating is slowly dwindling away. DON'T WASTE YOUR MONEY ON FRONTLINE!!
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Style Name: 6-MonthSize: Over 55 Pound Verified Purchase
Got this after reading many great reviews on Amazon and elsewhere. Loved the idea of it repelling the parasites rather than killing them AFTER they bite your pet as is the case with Frontline. We applied it per the directions and waited for the dog's itching and scratching to subside. After a day or two it seemed better. Then the scratching returned about 2 weeks later. Found several LIVE fleas on our dog, and worst of all they were filled with blood, meaning they had bitten and fed.

Reread the directions and it said to not apply more than once a week if needed. OK. A monthly application that may need to be applied weekly? So after only two weeks we re-applied it, again following the directions. Sad to say the poor dog has more fleas now than ever. We're returning the remainder for a refund.

If it would have worked as advertised this could have been a 5 star review. In our experience not only did it not work as advertised to repel the fleas, but it didn't even kill them at all. Perhaps we got a bad batch? We're now on Vectra 3D which costs twice as much and can only be gotten from the vet. After just one day the fleas (and scratching) are gone. I'm keeping my fingers crossed they don't return.

UPDATE: Tried the Vectra 3D and it also did not work. That's TWO top-rated topical flea treatments that had no positive results. It's entirely possible the Advantix II will work great for you... It just didn't work for us. Went to the vet and got Comfortis (oral tablet) and within a couple of hours all the fleas were dead. Yay! Moral of the story: topical applications simply do not work for our dog. Hopefully this helps someone else in a similar situation.
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