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The Antidote: Inside the World of New Pharma Kindle Edition
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|Length: 449 pages||Word Wise: Enabled||
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Top Customer Reviews
Werth's account of Vertex focuses mainly on the hepatitis C drug, with the cystic fibrosis drug playing a smaller but still important role. The previous book was much more science-heavy than this one, emphasizing the chemistry, biology and computer science that goes into the early stages of drug discovery. In spite of the intense scientific competition and research depicted in that volume (much of it spanning the late 80s and early 90s), Vertex did not bring a successful drug to market until 2010, underscoring the challenge of drug discovery in which you have to furiously paddle simply to stay afloat. The two books thus mirror two different phases of the company: the first dealing mainly with the science and the birthing pains of a new startup, and the second dealing with the transformation of the startup into a commercial enterprise. You will thus find much more of the business, legal and commercial aspects of drug development in this volume. Boardroom deliberations and the subtleties of drug pricing litter the narrative.Read more ›
What really touched me are the stories of individuals. The Bogers who "bore the torch" in the early days of doing great science and exploring the frontiers, the successors who financed and commercialized the founders' vision, the Wall Street analysts wanting to milk the new Pharmas like they did with the old, the patient advocates who wanted Vertex to remain true to its mission even when it is burning through hundreds of thousands of dollars a day... Those are real people competing viciously with selfish aims and playing out in a ruthless business world where billions of dollars would be won or lost on any single day. The deciding factors at the end of the day are two things: luck and balls.
Who doesn't become exited when warm humanitarian ideas and cold hard cash were tossed together and shaken violently by a group of crazy scientists? I will have that straight up any day.
I admire Vertex's quest for innovation. But 20 years of research before it can bring a drug to market is almost unbelievable. How they managed to finance this is amazing.
The key to all economic growth is innovation. One of the vital issues is how to finance this innovation which requires so much research. There aren't any easy answer. The US seems to be doing better than most other countries.
Most Recent Customer Reviews
Supposed to read this for a class by the end of the week but have yet yo start the book...Published 10 months ago by Aaron Henderson
Having been personally acquainted with some if not many of the issues discussed in The Antidote, I can only praise this book for its forthright stance. Read morePublished 11 months ago by William Daniel Turner
An incredibly detailed look inside the world of Pharma.
One gets to see the sausages getting made, and how many compromises are needed and how much perseverance and straight... Read more
I am hard pressed to think any reader beyond employees of Vertex would enjoy reading this book. I read it from cover to cover for educational purposes, only because I began... Read morePublished 15 months ago by Brian Kodi
Have not read as yet. It is the second book to the Billion Dollar Molecule.Published 23 months ago by Jan M. Kerhulas
I work in Pharma and the book goes a long way to depict the inner workings and dynamics of the industry with real-life happenings.Published on April 16, 2014 by C. J. McLaughlin-miley
I cannot figure why the author wrote this book, and he really does not explain the reason. The book is grossly tedious and filled with a seemingly endless cast of characters, only... Read morePublished on April 9, 2014 by Kathy in Omaha
Fascinating, accurate look inside pharmaceuticals! The author, Barry Werth, gets inside an industry that is often closed and difficult to explore. HE ROCKS!Published on April 9, 2014 by Peace Finder
An interesting look into the economics and politics of drug design and research. The science is heavy at times but the author does a good job of carrying the narrative.Published on March 20, 2014 by spsanders
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