- Hardcover: 864 pages
- Publisher: LWW; Fourth edition (February 5, 2010)
- Language: English
- ISBN-10: 0781750091
- ISBN-13: 978-0781750097
- Product Dimensions: 7.2 x 1.5 x 9.9 inches
- Shipping Weight: 3.8 pounds (View shipping rates and policies)
- Average Customer Review: 15 customer reviews
- Amazon Best Sellers Rank: #359,381 in Books (See Top 100 in Books)
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Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications Fourth Edition
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-- "This textbook covers a tremendous range of topics important in pharmacokinetics and pharmacodynamics. No other textbook does this as effectively as the Rowland and Tozer text." -- "I believe this book is the best written text for bridging the gap between basic PK and clinical PK."
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The previous PK book I read was Concepts In Clinical Pharmacokinetics by Joseph T. Dipiro and it is a shorter and simpler book than Rowland and Tozer. While "Concepts In Clinical Pharmacokinetics" was a delight to read, it is on the simpler side and a lot of concepts are left unexplained. When I was reading it, there were often moment of "How did he get from this to that?" or "Where this comes from?", and I had to stop reading and tried to derive the equations. In contrast, Rowland and Tozer explain the principles of PK in great details and often from multiple angles, so that the readers can fully appreciate how the concepts are linked together, how PK theories apply and how PK impacts pharmacology research and the drug discovery. The exercises are challenging, but not impossible. Well, a few of them are nearly impossible, but most of them can be worked out (even for someone of my background).
I would love to give it a 4.5 stars, but that is not an option. I do see there are a few shortcomings in this book. Although it is very detailed, it can be too detailed for beginners, except for students who has more time. It is best to start off with a short and easy to read introductory book. Yes, Rowland and Tozer have explained many concepts in multiple ways and this is generally good, except when you are busy. Sometime, I just feel like: I get your point already. The Final and the real criticism is that the book can be a bit dry. Unlike "Concepts In Clinical Pharmacokinetics", this is not a book to be breezed through.