Deadly Medicines and Organised Crime: How Big Pharma Has Corrupted Healthcare 1st Edition, Kindle Edition
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ISBN-13:
978-1846198847
ISBN-10:
1846198844
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Editorial Reviews
About the Author
Professor Peter C Gøtzsche graduated as a Master of Science in biology and chemistry in 1974 and as a physician in 1984. He is a specialist in internal medicine; he worked with clinical trials and regulatory affairs in the drug industry 1975–83, and at hospitals in Copenhagen 1984–95. He co-founded The Cochrane Collaboration in 1993 and established The Nordic Cochrane Centre the same year. He became professor of Clinical Research Design and Analysis in 2010 at the University of Copenhagen., Peter Gøtzsche has published more than 50 papers in ‘the big five’ (BMJ, Lancet, JAMA, Annals of Internal Medicine and New England Journal of Medicine) and his scientific works have been cited over 10000 times., Peter Gøtzsche has an interest in statistics and research methodology. He is a member of several groups publishing guidelines for good reporting of research and has co-authored CONSORT for randomised trials (www.consort-statement.org), STROBE for observational studies (www.strobe-statement.org), PRISMA for systematic reviews and meta-analyses (www.prisma-statement.org), and SPIRIT for trial protocols (www.spirit-statement.org). Peter Gøtzsche is an editor in the Cochrane Methodology Review Group.
--This text refers to an alternate kindle_edition edition.
Product details
- ASIN : B07WYC2244
- Publisher : CRC Press; 1st edition (August 21, 2019)
- Publication date : August 21, 2019
- Language : English
- File size : 1734 KB
- Simultaneous device usage : Up to 4 simultaneous devices, per publisher limits
- Text-to-Speech : Enabled
- Enhanced typesetting : Enabled
- X-Ray : Not Enabled
- Word Wise : Not Enabled
- Print length : 312 pages
- Lending : Not Enabled
- Best Sellers Rank: #168,545 in Kindle Store (See Top 100 in Kindle Store)
- Customer Reviews:
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4.8 out of 5 stars
4.8 out of 5
219 global ratings
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Top reviews from the United States
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Reviewed in the United States on August 31, 2018
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Whatever brought you to this place where you are considering reading this book... DO IT. I am a Registered Pharmacist who just finished a 42 year career. I wish I would have had this information on tap to balance the complete brainwashing that ALL health professionals obtain in school and as they continue in their fields. Folks, danger lurks in the fine print about these products. Here's a good motto for you -- Take NO drug without investigating it thoroughly. Do NOT take it on faith that your Doctor "would never give you anything that wasn't safe". Remember this one thing -- Vioxx killed 50,000 hapless souls. That's as many Americans that were killed in the Vietnam War. Merck saw problems, covered them up, and went about their business. This same thing has happened MANY times !
110 people found this helpful
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Reviewed in the United States on April 1, 2016
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Great read, I highly recommend this book to be able to make informed decisions when it come to taking pharmaceuticals. Don't be like me and trust in doctors without getting second opinions and educating yourself.
My son was severely damaged from deadly pharmaceuticals side effect ad they were treating him for asthma when he was hospitalized.
I wish I knew about the information that's written inr this book and his life would've most likely be different because I would've been able to make a better informed decision in his treatment and hospital stay.
Do yourself a favor and arm yourself with knowledge and purchase this book. It could make a difference in yours or someone you love life.
I strongly urge the purchasing of this book.
****** If you enjoyed my review please vote this review as helpful and feel free to ask me any additional questions and I'll answer them to the best of my abilities ******
My son was severely damaged from deadly pharmaceuticals side effect ad they were treating him for asthma when he was hospitalized.
I wish I knew about the information that's written inr this book and his life would've most likely be different because I would've been able to make a better informed decision in his treatment and hospital stay.
Do yourself a favor and arm yourself with knowledge and purchase this book. It could make a difference in yours or someone you love life.
I strongly urge the purchasing of this book.
****** If you enjoyed my review please vote this review as helpful and feel free to ask me any additional questions and I'll answer them to the best of my abilities ******
101 people found this helpful
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Reviewed in the United States on November 12, 2020
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The author is one of the co-founders of the Cochrane group, one of the most trusted institutions in medicine. Unfortunately, Gotzsche was ousted from Cochrane in 2018 (by Big Pharma decree) because of his criticism of the HPV vaccine.
This is yet another book on Big Pharma corruption. The author descibes in insidious and even tedious detail how doctors, medical research, medical journals, public health institutions, universities, the mainstream media and world governments have become corrupted by Big Pharma, which Gotzsche likens to organized crime.
(This comparison is actually an INSULT to organized crime since Big Pharma is far more ruthless and has killed far more people- as the author admits on the last page.) Gotzsche estimates that prescription drugs are the 3rd leading cause of death after heart attacks and cancer. Gotzsche also suspects that Big Pharma resorts to outright murder when bribery and intimidation don't work.
One of the most egregious examples of such corruption is in CH17 where the author says that Prozac was first approved in Sweden (even though suicide was already known to be a side-effect) through outright bribery. From Sweden, Prozac went on to become a blockbuster drug even though it continues to cause suicide! Another egregious example (not covered in this book) is the current opioid epidemic, which was started by Big Pharma for profit.
The book concludes with some obvious reforms (e.g. clinical drug trials should be performed by independent 3rd parties instead of allowing Big Pharma to conduct trials on their own products). But this will likely never happen because of Big Pharma's political influence.
One big question left unanswered by the author is WHY Big Pharma is so corrupt in the first place? Other industries (e.g. the electronics industry) are very profitable without routinely having to resort to gangster tactics. The answer is EROOM's law. The more familiar "Moore's law" is the doubling of transistors per silicon die every 2 years, which was achieved through increasingly finer lithography. This enabled the semiconductor industry to greatly reduce manufacturing costs and also resulted in 2x performance increases- a true WIN-WIN for industry and consumers. (Unfortunately, after decades of stunning success, Moore's law hit a power-performance wall in ~2004 and is now almost over.)
Big Pharma is beset by EROOM's Law, the opposite of Moore's law. Since the 1950s, drug development has dramatically slowed down and could even end by ~2040. Big Pharma is simply unable to innovate* and produce safe and effective drugs. So Big Pharma has to resort to "me-too" drugs, HYPE and outright FRAUD to increase profits. (Many new drugs are simply minor reformulations of previous drugs and are often less effective+safe than older+cheaper drugs, whose patents have expired.) The only reason this goes on then is consumer IGNORANCE and the BLIND (and near-religious) FAITH that most people have in doctors. In reality, Big Pharma is becoming increasingly useless. So I don't think reform is possible. The only FIX is for the "house of cards" to finally collapse. (Perhaps the government should then take over the production of generic drugs since China and India apparently won't manufacture them safely.)
Oliver Wendell Holmes said (in 1860), "If all the medicine in the world were thrown into the sea, it would be bad for the fish and good for humanity". This isn't true today (because some genuinely effective drugs were developed later in the so-called golden age of medicine), but it's becoming increasingly true of the current crop of drugs.
*Even the highly vaunted new class of cancer immunity drugs, which can cure a small % of patients, are a step back. The original cancer immunity treatment, "Coley's Toxin" (developed 100 years ago), was much cheaper and supposedly far more effective but was banned in the 1960s by the FDA in favor of chemotherapy and radiation. (Perhaps it should have been the other way around.)
Related reading: Medical Nihilism, Can Medicine Be Cured?
This is yet another book on Big Pharma corruption. The author descibes in insidious and even tedious detail how doctors, medical research, medical journals, public health institutions, universities, the mainstream media and world governments have become corrupted by Big Pharma, which Gotzsche likens to organized crime.
(This comparison is actually an INSULT to organized crime since Big Pharma is far more ruthless and has killed far more people- as the author admits on the last page.) Gotzsche estimates that prescription drugs are the 3rd leading cause of death after heart attacks and cancer. Gotzsche also suspects that Big Pharma resorts to outright murder when bribery and intimidation don't work.
One of the most egregious examples of such corruption is in CH17 where the author says that Prozac was first approved in Sweden (even though suicide was already known to be a side-effect) through outright bribery. From Sweden, Prozac went on to become a blockbuster drug even though it continues to cause suicide! Another egregious example (not covered in this book) is the current opioid epidemic, which was started by Big Pharma for profit.
The book concludes with some obvious reforms (e.g. clinical drug trials should be performed by independent 3rd parties instead of allowing Big Pharma to conduct trials on their own products). But this will likely never happen because of Big Pharma's political influence.
One big question left unanswered by the author is WHY Big Pharma is so corrupt in the first place? Other industries (e.g. the electronics industry) are very profitable without routinely having to resort to gangster tactics. The answer is EROOM's law. The more familiar "Moore's law" is the doubling of transistors per silicon die every 2 years, which was achieved through increasingly finer lithography. This enabled the semiconductor industry to greatly reduce manufacturing costs and also resulted in 2x performance increases- a true WIN-WIN for industry and consumers. (Unfortunately, after decades of stunning success, Moore's law hit a power-performance wall in ~2004 and is now almost over.)
Big Pharma is beset by EROOM's Law, the opposite of Moore's law. Since the 1950s, drug development has dramatically slowed down and could even end by ~2040. Big Pharma is simply unable to innovate* and produce safe and effective drugs. So Big Pharma has to resort to "me-too" drugs, HYPE and outright FRAUD to increase profits. (Many new drugs are simply minor reformulations of previous drugs and are often less effective+safe than older+cheaper drugs, whose patents have expired.) The only reason this goes on then is consumer IGNORANCE and the BLIND (and near-religious) FAITH that most people have in doctors. In reality, Big Pharma is becoming increasingly useless. So I don't think reform is possible. The only FIX is for the "house of cards" to finally collapse. (Perhaps the government should then take over the production of generic drugs since China and India apparently won't manufacture them safely.)
Oliver Wendell Holmes said (in 1860), "If all the medicine in the world were thrown into the sea, it would be bad for the fish and good for humanity". This isn't true today (because some genuinely effective drugs were developed later in the so-called golden age of medicine), but it's becoming increasingly true of the current crop of drugs.
*Even the highly vaunted new class of cancer immunity drugs, which can cure a small % of patients, are a step back. The original cancer immunity treatment, "Coley's Toxin" (developed 100 years ago), was much cheaper and supposedly far more effective but was banned in the 1960s by the FDA in favor of chemotherapy and radiation. (Perhaps it should have been the other way around.)
Related reading: Medical Nihilism, Can Medicine Be Cured?
21 people found this helpful
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Reviewed in the United States on May 17, 2017
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This is a terrific summary with enough detail and references to be your mainstay of the seriously deadly business of drugs. You will see many that you or family or friends take, and that are advertised on TV. Including cancer drugs, heart meds, NSAIDS, arthritis drugs, anti depressants etc. Most all rubbish in terms of actual P value and "randomized" trials. Most all drugs' trials are so manipulated from start to finish you won't believe it.
Doctors are pawns of the industry and after reading just this one book you will be more educated than them on the benefits or harms of the most popular medicines by a huge factor. But then they know nothing as they too are duped by the drug companies.
It is incredible that so many popular drugs used all the time today are almost completely unproven as beneficial against active placebos. forget about so called randomized and "blind" drug trials- they are almost always manipulated to produce higher benefit and lower risk. I always knew that 95% of all medicine was not only not necessary but harmful but I did not realize that the even the regulators, and the law enforcement of the FDA etc. are of almost no use, and even condone bad practices from within even their own corrupt ranks.
Thank God for the Cochrane Collaboration of which Gotzsche is cofounder for being unbiased and not connected to the drug manufacturing or selling industry. His vase experience as a doctor, salesman and academic have served us all. We should be eternally grateful for people like this.
This book should absolutely be required reading for all ... starting in high school.
Doctors are pawns of the industry and after reading just this one book you will be more educated than them on the benefits or harms of the most popular medicines by a huge factor. But then they know nothing as they too are duped by the drug companies.
It is incredible that so many popular drugs used all the time today are almost completely unproven as beneficial against active placebos. forget about so called randomized and "blind" drug trials- they are almost always manipulated to produce higher benefit and lower risk. I always knew that 95% of all medicine was not only not necessary but harmful but I did not realize that the even the regulators, and the law enforcement of the FDA etc. are of almost no use, and even condone bad practices from within even their own corrupt ranks.
Thank God for the Cochrane Collaboration of which Gotzsche is cofounder for being unbiased and not connected to the drug manufacturing or selling industry. His vase experience as a doctor, salesman and academic have served us all. We should be eternally grateful for people like this.
This book should absolutely be required reading for all ... starting in high school.
33 people found this helpful
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Top reviews from other countries
Martin Orsted
5.0 out of 5 stars
Great read, great passion, sad reality
Reviewed in the United Kingdom on February 22, 2014Verified Purchase
Peter Gøtzsche is in angry man. When you read his book it becomes clear why. In the book he documents with many examples the unhealthy relationship between the major pharmaceutical corporations on one side, and FDA and EMA, the universities and the medical doctors on the other side. It is an incestuous and downright corrupt relationship.
The author lives what he preaches, as he is a member of the Danish group Doctors without Sponsors, and he is clearly very knowledgeable and experienced. He has managed to produce a page turner here, and he doesn't pull his punches when he gives examples with names of doctors that have "prostituted" themselves and have become paid shrills for the industry, a fact they try to hide.
Reading the book you learn about the great crime Merck committed doctoring the data on Vioxx, which in the book is estimated to have cost 130,000 lives. You learn how the DSM manual is really a way of introducing new diagnoses that can then be monetized. An example is given of grief, where for DSM III the "acceptable" period for grief was one year before it was considered a clinical depression. In DSM IV this changed to two months, and in DSM V this became two weeks. You learn about how wholly unreliable and unscientific psychiatry is, and how dangerous happy pills really are, causing more harm than good. Actually, I started reading this book because of an article Peter Gøtzsche had in the Danish newspaper Politiken where he strongly recommended banning Psychopharma to kids, and generally criticized the extreme over use of Psychopharma. That got me interested and made me purchase and read the book.
Throughout the book it is clear that the author knows his area extremely well. The book is easy to read and in general whenever something new is introduced it comes with a good description. So the role of EMA and FDA is clearly explained, what an NSAID is (Vioxx is from that class of drugs), how evidence based medicine works, what the DSM is, ghost writing, how you can cheat with results, etc.
The book can be read by people without a medical background like me, but it might help reading for example Ben Goldacre's two books first, since this book is pretty fast moving covering loads of areas, so Ben's book would be good primers, but by no means necessary!
For me as a layperson some of the numbers that the author quotes seem a bit high, for example the estimate of 130,000 dead due to Vioxx, but in the book the author does go through the calculations that leads him to the conclusions, and they seem sound, so it could well be just me not used to seeing those kind of numbers attributed to a single medicine, that is downright scary!
As stated before the book is full of examples, and the author names the individual people involved and responsible by name in general. Frankly, to me that is gutsy, and I like that approach, it shows he is certain of his facts. Great read, I cannot recommend it enough, but it does paint a depressing picture. I guess the good news is that after reading the book you stand a better chance of becoming an informed consumer in this space, the last chapter has several recommendations, and that can only be a good thing.
The author lives what he preaches, as he is a member of the Danish group Doctors without Sponsors, and he is clearly very knowledgeable and experienced. He has managed to produce a page turner here, and he doesn't pull his punches when he gives examples with names of doctors that have "prostituted" themselves and have become paid shrills for the industry, a fact they try to hide.
Reading the book you learn about the great crime Merck committed doctoring the data on Vioxx, which in the book is estimated to have cost 130,000 lives. You learn how the DSM manual is really a way of introducing new diagnoses that can then be monetized. An example is given of grief, where for DSM III the "acceptable" period for grief was one year before it was considered a clinical depression. In DSM IV this changed to two months, and in DSM V this became two weeks. You learn about how wholly unreliable and unscientific psychiatry is, and how dangerous happy pills really are, causing more harm than good. Actually, I started reading this book because of an article Peter Gøtzsche had in the Danish newspaper Politiken where he strongly recommended banning Psychopharma to kids, and generally criticized the extreme over use of Psychopharma. That got me interested and made me purchase and read the book.
Throughout the book it is clear that the author knows his area extremely well. The book is easy to read and in general whenever something new is introduced it comes with a good description. So the role of EMA and FDA is clearly explained, what an NSAID is (Vioxx is from that class of drugs), how evidence based medicine works, what the DSM is, ghost writing, how you can cheat with results, etc.
The book can be read by people without a medical background like me, but it might help reading for example Ben Goldacre's two books first, since this book is pretty fast moving covering loads of areas, so Ben's book would be good primers, but by no means necessary!
For me as a layperson some of the numbers that the author quotes seem a bit high, for example the estimate of 130,000 dead due to Vioxx, but in the book the author does go through the calculations that leads him to the conclusions, and they seem sound, so it could well be just me not used to seeing those kind of numbers attributed to a single medicine, that is downright scary!
As stated before the book is full of examples, and the author names the individual people involved and responsible by name in general. Frankly, to me that is gutsy, and I like that approach, it shows he is certain of his facts. Great read, I cannot recommend it enough, but it does paint a depressing picture. I guess the good news is that after reading the book you stand a better chance of becoming an informed consumer in this space, the last chapter has several recommendations, and that can only be a good thing.
78 people found this helpful
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acidtest
5.0 out of 5 stars
Very factual and absorbing volume
Reviewed in the United Kingdom on July 15, 2016Verified Purchase
Gotzsche has the guts to take the pharma sector and the corrupt medical practitioners full on. Having myself been a victim in the receiving end of corrupt medical practices for 17 years, I know what he says is the truth and he offers some interesting empirical facts, hard to ignore. I take my hat off to him. In recent years, we are seeing a growing admirable bunch of honest professional scientists who take to the stage to denounce the corrupt link between current medical practice, the multi billion pharma sector and the medical regulators, and this can only be a good omen for justice. If anything, Gotzsche is very factual in his exposure, and having read other books and articles by other dissenting scientists, I know he has created a masterpiece, I recommend it to anyone interested in the subject.
24 people found this helpful
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Garthl
5.0 out of 5 stars
This is a book that shocks your cherished beliefs about the integrity of the medical profession
Reviewed in the United Kingdom on March 6, 2014Verified Purchase
The book is both compelling and deeply disturbing
Not only did it raise a different explanation of the effects of placebos but it raised some very disturbing questions about the effectiveness of certain drugs.
We have been fooled into thinking that the pharmaceutical industry is ably supporting the medical profession in improving the health of mankind. Far from it! It is more likely that the improvements in longevity have had little to do with the pharmaceutical industry. Most useful (and older) drugs were chance discoveries and the modern replacements are in a lot of cases money spinners that have been foisted on us - sometime through fraudulent science and most often through commercial inducement, undue influence and practises that are tantamount to bribery
Not only did it raise a different explanation of the effects of placebos but it raised some very disturbing questions about the effectiveness of certain drugs.
We have been fooled into thinking that the pharmaceutical industry is ably supporting the medical profession in improving the health of mankind. Far from it! It is more likely that the improvements in longevity have had little to do with the pharmaceutical industry. Most useful (and older) drugs were chance discoveries and the modern replacements are in a lot of cases money spinners that have been foisted on us - sometime through fraudulent science and most often through commercial inducement, undue influence and practises that are tantamount to bribery
22 people found this helpful
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MvB
5.0 out of 5 stars
Heavy going but what a worthwhile book!
Reviewed in the United Kingdom on April 7, 2014Verified Purchase
This book is a must to those who values their sanity, health and live however, reading it, for me personally, was a right slog for this is not the easiest book to read. Necessary, timely, important – yes. Well-researched – yes. Easy to read – no. Instead of building a logical string of how, the so-called “modern medicine”, overtook and overthrown the normal, “traditional” medicine and has conspired to destroy, kill and maim millions of people across the world, while polluting our environment, all in search of profit, we are left to read a parade of criminal rap-sheet of every pharmaceutical company on the planet. The good doctor seems not to realise that those who buy his book already know how pharmaceutical industry operates and take much better care of their bodies than the rest of the population – we cannot be shocked. The rest however, who will get a great deal of insight from this book that can go a long way towards saving their own lives as well as that of their families resulting from them reading this book, will find it a bit bland, dismiss it as sensationalist and be on their merry way to the early grave. An important and sincere book but an opportunity missed, I believe.
15 people found this helpful
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rod nelson 48
5.0 out of 5 stars
PLEASE PLEASE read this book.
Reviewed in the United Kingdom on July 27, 2014Verified Purchase
This book is a MUST READ for anyone who cares about 'health' provision. The story is relevant to everyone, whether they know it or not and Peter Goetsche has the credentials that make this book a potential game-changer for society. It is also a story that is quite breathtaking in its scope and should make us all angry with the magnitude of the crime against society that has been and is being committed. This is a story of theft and murder.
If you are a doctor, a politician or involved professionally, it is doubly important that you know what is in this book, and know that it is only as a result of you taking action that this crime can begin to be addressed.
Peter Goetsche has a whole lifetime of experience at the centre of the medical establishment and is a co-founder of the Cochrane Collaboration, which is like a beacon of clarity in the midst of a fog of confusion, spin and corruption.
If you are a doctor, a politician or involved professionally, it is doubly important that you know what is in this book, and know that it is only as a result of you taking action that this crime can begin to be addressed.
Peter Goetsche has a whole lifetime of experience at the centre of the medical establishment and is a co-founder of the Cochrane Collaboration, which is like a beacon of clarity in the midst of a fog of confusion, spin and corruption.
12 people found this helpful
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