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Diphenhydramine HCI 25 Mg - Kirkland Brand - Allergy Medicine and AntihistamineCompare to Active Ingredient of Benadryl® Allergy Generic - 600 Count

4.7 out of 5 stars 1,390 customer reviews
| 45 answered questions
About the Product
  • Relief from sneezing and running nose
  • Itching, Watery Eyes;Hay Fever symptoms;
  • Itching of Nose or throat.

Frequently Bought Together

  • Diphenhydramine HCI 25 Mg - Kirkland Brand - Allergy Medicine and AntihistamineCompare to Active Ingredient of Benadryl® Allergy Generic - 600 Count
  • +
  • Kirkland Signature Extra Strength Acetaminophen 500MG Caplets, 500-Count Bottle
  • +
  • Kirkland Signature USP Ibuprofen, 2 Bottles 200 mg of 500 Tablets Each
Total price: $30.26
Buy the selected items together


Product Description

Size: 600

Temporarily relief of the following symptoms: Sneezing and running nose; itching, watery eyes; hay fever symptoms; Itching of nose or throat .Temporarily relief of sneezing and running nose, itchy watery eyes, hay fever symptoms and itching of nose or throat.

Product Details

Size: 600
  • Item Weight: 7 ounces
  • Shipping Weight: 7.2 ounces (View shipping rates and policies)
  • ASIN: B000OTAJTO
  • UPC: 681131792578 096619536092
  • Average Customer Review: 4.7 out of 5 stars  See all reviews (1,390 customer reviews)
  • Amazon Best Sellers Rank: #809 in Health & Personal Care (See Top 100 in Health & Personal Care)

Important Information

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Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. Please see our full disclaimer below.

Customer Questions & Answers

Customer Reviews

Top Customer Reviews

Size: 600 Verified Purchase
Diphenhydramine is generic Benadryl. Amazon carries several brands of this medication for similar quantities in the same price range, so you should check what's currently available under Amazon Prime and go for the best price. Overall, though, it will be hard to go wrong with Amazon's generics, since they tend to be 10-20 times less costly than what local drugstores charge for similar quantities.

Benadryl was invented in 1943, and in 1946 the FDA approved its use as the first of the first-generation of antihistamines. Even though almost 70 years has passed, Benadryl is still considered one of the best and more powerful antihistamines. Its range of uses is pretty staggering:

1. It can be used for seasonal allergies like hayfever as well as allergic reaction to things like dog and cat dander.

2. It can help to alleviate the side-effects from psychotropic medications like antipsychotics.

3. It can be used to help with allergic reactions to other medications in general.

4. It is an anti-emetic and can help to alleviate nausea.

5. It is an anxiolytic (sedative) and can be used as a sleep aid. I have also known psychiatric units to use it in conjunction with other medications to sedate patients who are acting out.

6. It has anti-cholinergic properties and can be used to alleviate side-effects of choline-related medications like alpha-GPC and Huperzine-A.

7. It can help as a local anesthetic for itching (e.g., ringworm) when used topically (although this product would not be appropriate for that).

Diphenhydramine is not addictive although I have AA friends who feel strongly that its use might lead to a relapse.
Read more ›
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Size: 600 Verified Purchase
Diphenhydramine HCl is an excellent sleep aid and overall allergy relief medication. Safe to use and the Kirkland price is the best online that I've found. The company shipped my order out immediately and packaged the shipment really well. Won't hesitate to order again in the future and recommend this supplier.
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Size: 600
good price for the quantity, works just as good as the brand name, Benadryl. I know because I bought the biggest pack at the store (~50 count) for around $15. I never could take more because I always wanted to make it last. But with a 400 count bottle I can take more, which is what I need and still know I'll have plenty for the allergy season, (spring, summer)
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Size: 600 Verified Purchase
I've been purchasing this brand for several years now. I love the idea of having a bottle with a 600 count, that way I know they will last for quite awhile, since I have year round allergies, I don't want to run out.

I find that the Kirkland brand to be just effective as another well known brand.

I will continue to purchase this, because it definitely does work for me. The price is pretty good too.
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Size: 600 Verified Purchase
Good product at a great price.

If you take an antihistamine such a Benadryl this is a much cheaper
alternative. The pills are very small and easy to swallow.
One of the best deals I've ever found of any kind.
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Size: 600 Verified Purchase
I was really glad to find diphenhydramine in a tablet form. I personally don't mind whether it's a tablet or a capsule, but my beagle mix is easier to fool when I give him a tablet in peanut butter. He doesn't hear a capsule crunching, so he takes one little bite (just to make sure) and then swallows it whole. He is allergic to everything in the front yard and this really helps him with his itchy belly. And the price is great!
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Size: 600 Verified Purchase
My wife suffers from numerous allergies. The Kirkland Allergy Medicine is simply 25 mg size generic Benadryl ( I.e diphenhydramine.) You get a huge amount of tablets for a fraction of the cost of the brand name version. These seem to be equivalent in effectiveness, with prompt shipping and delivery. I really can't think of much more to say except that we have been completely satisfied with the product, price and transaction. We have had absolutely no problems with any of the Kirkland brand generic medications, including this one. Diphendramine can have its own downsides, such as thickening of mucous, drying of sinuses and drowsiness, so do keep that in mind. However, for people with high blood pressure, many of the non- sedating meds pose their own problems and for that reason I am uncomfortable recommending any medication without adding the warning to check first with your doctor before purchasing medication, especially in today's litigious society we live in. Caveat emptor:-)
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Size: 600 Verified Purchase
This was a very good deal for these pills that are the same as Benadryl, which costs much more. Prompt delivery also.
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