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The Doctors' Plague: Germs, Childbed Fever, and the Strange Story of Ignac Semmelweis (Great Discoveries) Paperback – November 17, 2004
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The "riveting" (Houston Chronicle), "captivating" (Discover), and "compulsively readable" (San Francisco Chronicle) story of the discovery that handwashing helps prevent the spread of disease.
Surgeon, scholar, best-selling author, Sherwin B. Nuland tells the strange story of Ignác Semmelweis with urgency and the insight gained from his own studies and clinical experience. Ignác Semmelweis is remembered for the now-commonplace notion that doctors must wash their hands before examining patients. In mid-nineteenth-century Vienna, however, this was a subversive idea. With deaths from childbed fever exploding, Semmelweis discovered that doctors themselves were spreading the disease. While his simple reforms worked immediately―childbed fever in Vienna all but disappeared―they brought down upon Semmelweis the wrath of the establishment, and led to his tragic end.
- Print length208 pages
- LanguageEnglish
- PublisherW. W. Norton & Company
- Publication dateNovember 17, 2004
- Dimensions5.5 x 0.7 x 8 inches
- ISBN-10039332625X
- ISBN-13978-0393326253
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Product details
- Publisher : W. W. Norton & Company; Reprint edition (November 17, 2004)
- Language : English
- Paperback : 208 pages
- ISBN-10 : 039332625X
- ISBN-13 : 978-0393326253
- Item Weight : 6.4 ounces
- Dimensions : 5.5 x 0.7 x 8 inches
- Best Sellers Rank: #194,191 in Books (See Top 100 in Books)
- #204 in History of Medicine (Books)
- #448 in Medical Professional Biographies
- #639 in History & Philosophy of Science (Books)
- Customer Reviews:
About the author

Sherwin B. Nuland is Clinical Professor of Surgery at Yale University School of Medicine and a Fellow at Yale's Institute for Social and Policy Studies. He is the author of over ten books, including the National Book Award-winning, HOW WE DIE: Reflections on Life's Final Chapter, an inquiry into the causes and modes of death that spent 34 weeks on the New York Times best-seller list. In addition he is a contributor to leading publications including the New Yorker, the New Republic, and the New York Review of Books.
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Customers find the book compelling and well-written. They describe it as informative, interesting, and well-researched. The story holds their interest and is considered one of the most affecting books they've read.
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Customers find the book's pacing compelling. They describe it as a well-written true story that blends literary finesse with scientific precision. The book is described as concise yet thorough, and a good read overall. Readers appreciate the lucid presentation of the story, which is easy for non-scientists to understand.
"This is a simple story, and today it is hard to imagine that there was a time that this could have happened. A girl in Vienna, Austria in the..." Read more
"...But the overall result is an excellent presentation not only of Semmelweis’s life but the context in which he lived and the horrors of the disease..." Read more
"...had been sweeping though urban hospitals in the early 19th Century is concise, thorough, and well done...." Read more
"...A stunning account by the late, great Sherwin Nuland." Read more
Customers find the book informative and interesting. They appreciate the well-researched content and thorough writing style that combines literary finesse with scientific precision. The author does an excellent job explaining the problems faced by medicine during that time period.
"...This new book on Ignac Semmelweis is well-researched and it adds greater detail to the sad story of politics, conservatism, and pride which caused..." Read more
"...sweeping though urban hospitals in the early 19th Century is concise, thorough, and well done...." Read more
"...with non-medical background because the author did a very good job explaining the problems that medicine faced that time...." Read more
"It was interesting to read this book. I was familiar with the story of Semmelweis having read The Cry and the Covenant many years ago...." Read more
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- Reviewed in the United States on August 27, 2015This is a simple story, and today it is hard to imagine that there was a time that this could have happened.
A girl in Vienna, Austria in the 1840s meets a dashing young college student. It is such a lovely relationship, but soon, she gives herself to him--- over and over and over. She becomes pregnant and the dashing student blames himself for his “dallying” with this girl. Of course, he takes no responsibility for this pregnancy.
The girl’s mother died years ago, but her father has always been so understanding, he will have a solution. Instead, he flies into a rage.
The girl stays with her friend Liesl, and she makes frequent trips to the Allgemeine Krankhausen, a huge hospital, the pride of Vienna. Since the 18th century fine hospitals had been built all over Europe, coupled with schools of medicine. Hospitals were a tremendous benefit for the lower classes, but affluent families continued to be treated in their own homes.
The girl (author Nuland never gives her a name) scouts out the hospital in her many quiet visits. From Liesl she learns that there are two obstetric divisions—one run by doctors and the other by midwives. She should ask for the one run by midwives, Liesl advises. “Stay away from the prying hands of the medical students,” she says.
The day comes when the girl’s water breaks and she and Liesl walk over a half mile to the Allgemeine Krankenhaus They are greeted by a friendly nurse, and she is assigned to the first division, the one run by doctors. No, she cannot go to the second division. This is where she is assigned.
The girl is given her bed, and visited by nurses, doctors and medical students. The routine for the students is to visit the “Deadhouse”, where they can examine corpses of those patients who have recently died. Then the students come up to examine these young women, about to give birth.
The girl has a long labor, but finally delivers a fine young boy, whom she names for her father. Surely, she thinks, “When I show my father the baby he will forgive me.”
Shortly after the birth, however, the girl develops a high fever and her body begins to fill with gas. She vomits, and cannot take food. She becomes cold and clammy, then delirious. Finally, three days after the delivery, she dies.
This is 1847, and the author has used this fictional story to lead us into the story of how doctors eventually discovered that they were the very causes of death of so many young women. Fully one out of every six women in this first division at Allgemeine Krankenhaus died of puerperal fever, or childbed fever.
Every morning, young doctors would open up bodies of deceased women and find their uteruses inflamed and filled with pus. Then they would proceed directly to the first division and examine healthy young women about to give birth. In the second division, midwives examined the young women, but they did not visit the deadhouse. The mortality rate in second division was much lower.
At that time no one knew about germs or infection. They thought that the sickness that swept over these women came from bad vapors or perhaps some mysterious aura. They thought there might be a connection between the changes in a woman’s body that allow her to give milk to her child, or a blockage of the amniotic fluid (lochia). Everything but the thought that it could be doctors with filthy fingers!
When we read about doctors wading in bodily fluids, inflamed flesh, pus and a putrid stench, and then proceeding directly to examine healthy women, we can hardly imagine that anyone could have ever been that stupid.
Along comes Ignác Semmelweis. Born in Hungary in 1818, Ignác starts out learning to become a lawyer, then changes to medicine. He studies at the University of Vienna one year, then changes to the University of Pest back in Hungary, then back to Vienna to finish and get his degree. Nuland has studied Semmelweis a great deal before writing this book.
In 1847, as Semmelweis concluded that doctors and students were conveying the disease, he set up bowls of chloride solution at the entrance to the maternity ward and ordered students to wash their hands before entering the ward.
Johann Klein, Semmelweis’ chief at the Vienna lying-in hospital, was an Austrian doctor who followed all the rules and was beholden to the royal apparatus, had been a stern teacher of young doctors and insisted on thorough autopsies and clinical observations of cadavers. He did everything in his power to suggest that puerperal fever, and all the deaths, were caused by the ventilation, the walls, anything but by his doctors.
Semmelweis had a lot of characteristics that made him hard to get along with. He had a habit of really haranguing any students or doctors who failed to use the chloride solution upon entering the maternity ward. And he failed to put his theories about infection into print. He soon moved to the lying-in hospital in Pest, Hungary. There he found the same problem—doctors handling a cadaver filled with pus and stinking to high heaven, and then proceeding to operate on a theretofore uninfected patient. He nagged them about using the chloride. And still, they resisted.
Back in Austria, someone wrote an article in the Vienna Medical Weekly, saying that one would expect that now (several years after Semmelweis had departed) this chloride-washing theory had been discredited.
Semmelweis was not easy to get along with. He was impatient, impetuous, single-minded and blustery. He did not make friends easily. Yet, in 1856, at the age of 38, he married a beautiful young woman, daughter of a prosperous Hungarian merchant.
Finally, in 1861 Semmelweis published his book, The Etiology, the concept and the prophylaxis of Childbed Fever. It was met with indifference and opposition by leading obstetricians, which set Semmelweis into a rage.
Soon, Semmelweis’ behavior became more bizarre than usual, with strange sex habits, including openly consorting with a prostitute, and rambling speech. He was clearly suffering from some sort of dementia. He was committed to a hospital for the insane and died in August 1865. Four years later, scientists discovered microbes in chains, later to be called streptococci, and in 1879 Louis Pasteur connected Semmelweis’ work with the streptococci to pronounce that “it is the doctor and his staff that carry the microbe from a sick woman to a healthy woman.”
- Reviewed in the United States on December 21, 2007I read the The Cry and the Covenant when I was around 14 years old and it is one of the most affecting books I've ever read. This new book on Ignac Semmelweis is well-researched and it adds greater detail to the sad story of politics, conservatism, and pride which caused countless unnecessary and tragic deaths of young women and children. Given that medical mistakes are all too common, this should be required reading for anyone in the medical field!
- Reviewed in the United States on July 11, 2024Nuland points out a few times in this book how a type of mythology has built up around Ignace Semmelweis. Semmelweis is usually viewed as a lone revolutionary, someone who recognized how childbed fever was spread and saved thousands of lives but who was simply ahead of his time. As is often the case, there is a good deal of truth in the historical image. Semmelweis had the first insight that puerperal fever was passed on by physicians and aides who often went directly from autopsies or ill patients to other women. His dogged (and often abrasive) insistence on hand washing and cleanliness saved thousands from pain and death. Nuland spells this out well.
But he also details the full context of Semmelweis’s life and his failings. Despite encouragement from friends, monetary incentives, and an awareness of its importance, Semmelweis absolutely refused to publish his findings and his method. While he personally repudiated and often loathed those who clung to conservative ways because of tradition or status in the medical establishment, he did virtually nothing to publicly show their flaws. A few of those who agreed with him wrote about his method’s success but he himself was basically forgotten until decades after his death. Beginning with what was described as a “playful, jocular nature,” Semmelweis became a bitter and resentful man who died in what was then called an insane asylum. Nuland (with the reader) tries to understand why Semmelweis refused to publish his work and why his personality changed so drastically. As Nuland puts it well, Semmelweis is commonly viewed as a hero destroyed by entrenched malevolent forces but a more complete image would be that portrayed by Sophocles – a hero brought down (to a great extent) by his own flaws.
Nuland spends the first 72 pages laying out the history of childbed fever and the medical understanding and approach to it up to Semmelweis so the book can a bit slow to get into. But the overall result is an excellent presentation not only of Semmelweis’s life but the context in which he lived and the horrors of the disease with which he dealt.
- Reviewed in the United States on May 15, 2014Doctors' Plague was ok but this MD writer with so many books to his credit seemed to have an unwarranted ego need to prove that his theory, alone, is the correct one in regard to Semmelweis. With all due respect, the writing style is not that great, either, in my estimation.
Top reviews from other countries
Laura O'ReillyReviewed in Canada on June 23, 20145.0 out of 5 stars Sad story of a misunderstood doctor and he's plague
This is a great book about the doctor who's discovery of Puerperal fever cause, and the prevention of it. It was really sad to read about how his theory was misunderstood and mock, and that he went insane in the end.
MeReviewed in the United Kingdom on December 28, 20145.0 out of 5 stars Five Stars
fascinating








