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Dale Bredesen

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The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline Hardcover – Illustrated, August 22, 2017

by Dale Bredesen (Author)

4.5 5,155 ratings

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The instant New York Times and Wall Street Journal bestseller

A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline.

Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease.

In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene.

The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer’s brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.

From the Publisher

From author Dale E. Bredesen, MD. The groundbreaking books offering hope

Editorial Reviews

Review

"Alzheimer’s is a disease for which there is no cure. Dr. Bredesen’s experimental program gives me hope that there are actions we can all take to care for our brains and keep Alzheimer’s at bay."
—Maria Shriver, Today Show

"The End of Alzheimer’s is a monumental work. Dr. Bredesen completely recontextualizes this devastating condition away from a mysterious and unsolvable process to one that is both preventable and, yes, reversible. Pinning our hopes on pharmaceutical research to develop a miraculous wonder drug has left both physicians and patients empty handed. But now, this comprehensive approach offers solid results, bringing hope to so many."
—David Perlmutter, MD, Board-certified neurologist and author, #1 New York Times bestseller, Grain Brain, and Brain Maker

"The End of Alzheimer's, for the first time, synthesizes the latest science into a practical plan that can reverse Alzheimer's and dramatically improve brain health and function. If you have a brain, read this book."
—Mark Hyman, MD, author of the #1 New York Times bestseller Eat Fat, Get Thin

"This book represents a major turning point in our approach to Alzheimer’s disease, from viewing it as a mysterious and incurable affliction that is governed almost exclusively by our genes, to understanding it as a multifactorial condition that can be prevented and even reversed largely through nutrition and lifestyle change. For the first time ever, patients and families affected by Alzheimer’s—as well as those at high risk for this devastating disease—truly have a reason to be hopeful."
—Chris Kresser, M.S., L.Ac Founder, Kresser Institute for Functional & Evolutionary Medicine, Author of the New York Times best seller The Paleo Cure

"The End of Alzheimer’s is a masterful, authoritative, and ultimately hopeful patient guide to functional medicine for your brain. It will help you prevent and reverse Alzheimer’s disease, whether you have the ApoE4 gene or not. My patients fear Alzheimer’s more than any other diagnosis. This is the book to transmute fear into action."
—Sara Gottfried, MD, New York Times bestselling author of Younger

"Having spent several years implementing many of Dr. Bredesen's insights in my patients, I can assure you that following his advice can save yourself, your loved ones, and your friends from suffering from this preventable and reversible curse."
—Steven Gundry, MD, author of the New York Times bestseller The Plant Paradox

"Dr. Dale Bredesen is a world class neuroscientist/neurologist who through his innovative and exacting research has discovered a safe and effective approach to the prevention and treatment of Alzheimer's disease that will revolutionize the way we think about the disease."
—Jeffrey Bland, PhD, FACN, FACB; President, Personalized Lifestyle Medicine Institute

"The End of Alzheimer's offers a new beginning in Medicine — changing the focus from a singular disease to recognizing the systems-based approach required to care for the whole person. Dr. Bredesen translates the knowledge of science to the wisdom that helps to heal our people . . . and provide a vision for the end of Alzheimers!"
—Patrick Hanaway, MD, Founding Medical Director, Director of Research, Center for Functional Medicine, Cleveland Clinic

"In this engaging, heartfelt, and insightful book, Dr. Bredesen elucidates a bold new approach to Alzheimer's, rooted in decades of his own pioneering research. A must read for anyone wondering what can be done for this dread disease, whether for themselves, a loved one, or a patient."
—Nathan Price, PhD, Professor & Associate Director of the Institute for Systems Biology

About the Author

Dale Bredesen, M.D., is internationally recognized as an expert in the mechanisms of neurodegenerative diseases such as Alzheimer’s disease. He graduated from Caltech, then earned his M.D. from Duke University Medical Center in Durham, North Carolina. He served as chief resident in neurology at the University of California, San Francisco (UCSF) before joining Nobel laureate Stanley Prusiner’s laboratory at UCSF as an NIH postdoctoral fellow. He held faculty positions at UCSF, UCLA, and the University of California, San Diego. Dr. Bredesen directed the Program on Aging at the Burnham Institute before coming to the Buck Institute in 1998 as its founding president and CEO. He is the chief medical officer of MPI Cognition.

Excerpt. © Reprinted by permission. All rights reserved.

Meet Kristin.

Kristin was suicidal. Years before, she had watched in despair as her mother’s mind slipped away, forcing her to enter a nursing home after she could no longer recognize family members, let alone care for herself. Kristin had suffered along with her mother, who at the age of 62 had begun an 18‑year decline into Alzheimer’s disease. And at the end Kristin had suffered alone, for her mother was no longer sentient.

When Kristin was 65, she began to experience her own cognitive problems. She got lost when driving on the freeway, unable to remember where to get off and on, even on familiar routes. She could no longer analyze data critical to her job, or organize and prepare reports in a timely fashion. Unable to remember numbers, she had to write down even four digits, not to mention phone numbers. She had trouble remembering what she had read, and by the time she reached the bottom of a page had to start at the top again. Reluctantly, Kristin prepared her resignation. She began to make mistakes more and more frequently, often calling her pets by the wrong names and having to search to find the light switches in her own home, even though she had flipped them on and off for years.

Like many people, Kristin tried to ignore these symptoms. But they got worse and worse. After two years of unremitting cognitive decline, she consulted her physician, who told her she was becoming demented just as her mother had, and there was nothing he could do for her. He wrote “memory problems” on her chart, and because of that, she was unable to obtain long-term care insurance. She underwent retinal scanning, which revealed the Alzheimer’s-associated amyloid. She thought about the horror of watching her mother decline, about how she would live with progressive dementia and no long-term care, about the lack of treatment. She decided to commit suicide.

She called her best friend, Barbara, explaining, “I watched what my mother went through as she slipped away, and there is no way I will allow that to happen to me.” Barbara was horrified to hear Kristin’s saga. But unlike when other friends had fallen victim to dementia, this time Barbara had an idea. She told Kristin about new research she had heard about, and suggested that rather than ending her life, Kristin travel several thousand miles to the Buck Institute for Research on Aging, just north of San Francisco. In 2012, Kristin came to see me.

We talked for hours. I could offer her no guarantee, no example of any patient who had used the protocol—nothing more than diagrams, theory, and data from transgenic mice. In reality, Barbara had been premature in sending her to the Institute. And to make matters worse, the protocol I had developed had just been turned down for its first proposed clinical trial. The review board felt that it was “too complicated,” and pointed out that such trials are meant to test only a single drug or intervention, not an entire program (ah, if only diseases were that simple!). So all I could do was to go over the various parts of the protocol and recommend that she take these to her physician back home, asking him if he would work with her. She did that, and so began what has become the ReCODE protocol.

Three months later, Kristin called me at home on a Saturday to say she could not believe the changes in her mental abilities. She was able to work full-time again, to drive without getting lost, and to remember phone numbers without difficulty. She was feeling better than she had in years. When I put the phone down, what rushed into my mind were the decades of research, the countless hours at the whiteboard with lab members and colleagues, the arguments with myself about each detail of the theory and treatment approach. All of this had not been in vain; it had pointed us in the right direction. Of course Kristin was only one person—as they say, an “n of one”— and we needed to see similar results in thousands and ultimately in millions. I thought back to the doctor who told his patient, “You are just an anecdote; you are not statistically significant.” To which his patient replied, “Well, my family says that I am significant. Besides, I’m healthy once again, so I don’t care about statistics.” Indeed. Every fundamental change needs to start somewhere—every successful approach must start with Patient Zero—and Kristin was Patient Zero.

Product details

Publisher ‏ : ‎ Avery; 1st edition (August 22, 2017)
Language ‏ : ‎ English
Hardcover ‏ : ‎ 320 pages
ISBN-10 ‏ : ‎ 0735216207
ISBN-13 ‏ : ‎ 978-0735216204
Item Weight ‏ : ‎ 2.31 pounds
Dimensions ‏ : ‎ 6.2 x 1 x 9.3 inches

Best Sellers Rank: #11,637 in Books (See Top 100 in Books)
- #7 in Alzheimer's
- #12 in Dementia
- #13 in Nervous System Diseases (Books)

Customer Reviews:
4.5 5,155 ratings

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Customers say

Customers find the book informative and helpful, providing crucial information on tests and supplements. They describe it as an effective protocol that works well. The diet recommendations include eliminating sugar and reducing habitual foods that interfere with proper functioning. Exercise is also mentioned as a key component of the plan. Some customers mention that the book is written for the layperson to understand, while others feel it lacks a detailed action plan.

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Information quality Effectiveness Diet Exercise level Gene profile Ease of reading Value for money Disease treatment

552 customers mention "Information quality"519 positive33 negative

Customers find the book informative and helpful. They say it provides advice on things to prevent cognitive decline and improve memory. The suggestions are fully explained and make a difference. The book offers many steps to get healthy, not just a single pill solution.

"...of the 36 inducing factors in your brain." Those 36 factors are clearly laid out and I believe they are not difficult to control...." Read more

"...Good, practical and tested advice from this researcher." Read more

"...acid supplements, like fish or krill oil, Vitamin E, basic nutrients for brain health, such as Calcium, Magnesium and Vitamin D, Zinc for the immune..." Read more

"...Other than extensive blood testing, this book suggests dietary changes. Many of the dietary suggestions I completely agree with, but some I do not...." Read more

31 customers mention "Effectiveness"27 positive4 negative

Customers find the book's protocol effective for treating Alzheimer's. They say it works well and is helpful. The research is still young, but the percentage of success is incredible, with over 90% remissions. While difficult to understand at first, the work is exciting if it works.

"...has driven home in this book how critical it is to follow his protocol in order to maintain, and most of all improve my brain health...." Read more

"...been having significant success in reversing symptoms and restoring normal functioning to hundreds of patients in recent years after many years of..." Read more

"...His protocol starts with lifestyle and behavior changes and makes the important leap forward of including precision diagnosis and treatment of..." Read more

"...the plan works and is very helpful. His supplementation and diet suggestions make a lot of sense, and weren't too far from how we eat anyway...." Read more

11 customers mention "Diet"8 positive3 negative

Customers like the diet. They mention avoiding sugar and habitual foods that interfere with proper nutrition. The book provides advice on correcting nutritional deficiencies, gluten, and sugar. It also mentions avoiding GMO and processed foods.

"...Diet is very important in slowing dementia, but physical and mental support is just as important. UPDATE 05/25/20:..." Read more

"...The most dramatic for me has been the elimination of sugar and reduction of habitual foods that interfere with proper brain activity...." Read more

"...There are so many foods, vitamins, supplements, powders, pro-biotics, pre-biotics, oils, etc to try...." Read more

"...to take and how to improve our poor diet, what foods to add, what foods to stop, how to overcome our reluctance to exercise and our poor sleep...." Read more

10 customers mention "Exercise level"10 positive0 negative

Customers find the book helpful for exercise and nutrition. It recommends getting plenty of exercise and eating a Mediterranean diet. The book provides information on how to overcome reluctance to exercise and poor sleep, as well as what foods to avoid and supplements to take. They find it a great support for their practice and well-organized.

"...It gives you sound nutritional advice and emphasizes the importance of exercise, not only for your immune and muscle heath, but mainly for supplying..." Read more

"...These chapters help provide the support and encouragement needed to make those changes. 4...." Read more

"...diet, what foods to add, what foods to stop, how to overcome our reluctance to exercise and our poor sleep...." Read more

"...Such as: good sleep, quality food, fasting 12+ hours at night, exercise and a variety of important tests to gauge how your system is (mal)functioning..." Read more

9 customers mention "Gene profile"9 positive0 negative

Customers find the gene profile helpful for those with genetic predispositions and no symptoms yet. They say it provides diet and lifestyle advice to combat genetic predisposition and environmental concerns. The book also recommends a DNA test with 23andMe to see if a person has the Alzheimer's gene, as well as the ReCODE protocol, including lab tests.

"...The book thoroughly explains the ReCODE protocol, including lab tests...." Read more

"...book has helped me understand and identify key diet, toxic and genetic factors to work on with my Functional Medicine MD." Read more

"...He also recommends a DNA test with 23andMe to see if a person has the Alzheimer's gene...." Read more

"...Doesn't matter if you have no symptoms, family history or genetic traits. ---..." Read more

190 customers mention "Ease of reading"124 positive66 negative

Customers have different experiences with the book's ease of reading. Some find it well-written and easy to understand, even though it contains medical information. They appreciate the casual format that makes it clear. Others find the content too technical and complicated, requiring careful reading and some advanced degrees.

"...I was very happy to see that it was written in a casual format that intentionally makes it easier for the rest of us...." Read more

"Good science and well-explained...." Read more

"...It can get technical at times but mostly easy for the regular joe to read and take notes from. Good, practical and tested advice from this researcher." Read more

"Love the detail, the rationale for every recommendation given...." Read more

40 customers mention "Value for money"12 positive28 negative

Customers have different views on the book's value for money. Some find it informative and thorough, while others feel it provides unrealistic suggestions and requires expensive testing and treatment that the average person cannot afford.

"...Dr. Bredesen's claim to REVERSE Alzheimer's is arrogant, bold and irresponsible and is preying on the vulnerability of those affected by this..." Read more

"...She did, and the bill was very modest. I only have basic Medicare, no supplemental insurance...." Read more

"...We had to pay for the office visits and her supplements. A small price for a better life...." Read more

"...It can get very expensive so I have to pick and choose what is essential for me...." Read more

20 customers mention "Disease treatment"11 positive9 negative

Customers have different views on the treatment of Alzheimer's disease. Some find it hopeful and able to reverse cognitive decline, describing the disease as modifiable with an integrative approach. Others say there is no magic bullet and that the multifaceted nature of the disease requires multiple treatments.

"...but mainly for supplying critical growth factors that allow your brain to heal more quickly...." Read more

"...as daily exercise etc...I firmly believe that this alone will NOT REVERSE cognitive decline unless the various areas of sensitivities and allergic..." Read more

"...the best protocol to date to avoid Alzheimer's disease and reverse mild cognitive decline...." Read more

"His book was misleading, there is no cure for Alzheimer’s and certainly no reversal...." Read more

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UPDATE: ONE star! Choose the Sherzai's book or Keep Sharp by Sanjay Gupta
Reviewed in the United States on August 25, 2017
Verified Purchase
This part of my review is an update. My opinion of this book has changed. While a lot of my review is still accurate, and I based it on just diet and lifestyle changes without any products or services, Bredesen has turned his focus to unproven products and methods that are very expensive and do not seem to be beneficial. In other words, a lot of hogwash. Instead, I now highly recommend The Alzheimer's Solution by Drs Dean and Ayesha Sherzai. Unlike Bredesen's study of just 10 people, the Sherzais have studied thousands of participants over many years and are respected around the globe. There are no controversies with their program. Alzheimers cannot be cured. But it can be prevented or pushed back so we can enjoy life longer. Their program does not require the use of supplements or tests that prove nothing, like the Bredesen Protocol. It's all about lifestyle changes. Nutrition. Exercise. Stress reduction. Good sleep. And optimizing the brain through various techniques such as learning new skills. You can find all of their advice online for free or get their book. Also, Dr Sanjay Gupta has a book, Keep Sharp, that is very similar to what the Sherzais teach. Get either or both. But don't buy the Bredesen Protocol.

I am hesitant to update my star rating just yet because it might make my review fall off the first page and I want people to read this. Please look for an alternative program.

Original review is below
______________________

My mother, and roommate, has frontal lobe dementia and, they believe, Alzheimers. Watching her decline has been heart wrenching, and I'm constantly trying to find ways to make her life better. I worry not only about Mom, but about myself. I believe that I am on the same path.

I first heard of the Bredesen Protocal last winter, when Maria Shriver discussed it on the Today Show. I quickly researched it as much as possible, but info was limited. I had a feeling a book was forthcoming, so I anxiously awaited it's release. I was worried The End of Alzheimer's would contain too much technical information that I might not be able to understand. I was very happy to see that it was written in a casual format that intentionally makes it easier for the rest of us. The details are clear, the tone is casual, and it's easy to follow.

As I read through this book, I was surprised by how many points were familiar to me. That's me! I do that! Oh heck! It was as enlightening as it was scary. Living with Mom, I also live in fear because I know I'm on the same path she struggles down every day. That's my future.

On page 97, Bredesen says "How to give yourself Alzheimer's. Live your life in a way that keeps your brain supplied with as many as possible of the 36 factors that influence whether APP gets cut into the destructive quartet or the beneficial duo. How to prevent it. Live your life in a way that minimizes the number of the 36 inducing factors in your brain." Those 36 factors are clearly laid out and I believe they are not difficult to control.

Several years ago, I struggled with brain fog and often had difficulty remembering numbers for even a couple of minutes. I also was overweight and had heart problems. I reached a point where I thought I would die, so I wrote my will and made plans for my dogs after I was gone. Then I said enough was enough, and I dramatically changed my lifestyle. I cut out processed foods, ate lots and LOTS of vegetables and fresh fruits, especially leafy greens and berries. I ate wild caught fish, but no other animal products. My diet was low in grains. I used the USDA Super Tracker to make sure that my diet exceeded the RDA for every nutrient they tracked. There's a lot more to it, but I was eating all the time and I exercised every single day. Within a few weeks, I had much more energy. Within a few months, my brain was on FIRE! But then...

I started a new job and everything about my lifestyle and schedule changed. Long story short, I fell back into old habits, abandoned my perfect diet and exercise program, and gradually regained weight. I also started losing clarity and life became more difficult. I recognize that. And I know that I alone can change that.

I'm so very glad to have read the Bredesen Protocol because I know now, more than ever, the importance of getting back on track. I am making a serious effort to change my future. I believe this book can help. I have already marked my calendar and plan to follow up on this review in 3 months and again in six months. Mom may be too far along, I don't know, but it's worth trying for both of us. Dr. Bredesen states in the book that his protocol may not work for frontal lobe and other types of dementias. It has only been tested on Alzheimers. I feel that it's still very important to heed his advice, as Alzheimers often doesn't get a definite diagnosis until after death.

___________________-
Note that the above is the original review. Please read my update at the beginning of the review.

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Good to know
Reviewed in the United States on December 18, 2024
Verified Purchase
You can never have enough knowledge if you or a loved one might face dementia or Alzheimer's. I watched the documentary then followed up with this book. It can get technical at times but mostly easy for the regular joe to read and take notes from. Good, practical and tested advice from this researcher.

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Debra Martinka
Get more exercise, exercise your brain and correct nutritional deficiencies. This book breaks it all down and shows you how.
Reviewed in the United States on January 22, 2018
Verified Purchase
Good science and well-explained. This book may not be the end of Alzheimer's for everyone, but I am convinced that it can make a huge difference in the lives of many people. The author has over 20 years of research experience and he has applied his knowlegde to breaking down Alzheimer's according to the many small components that can lead to disease. The basic approach is to fix the underlying metabolic functions that have gone awry - mitochondiral inefficiency, insulin resistance, inflammation and nutritional deficiency. It gives you sound nutritional advice and emphasizes the importance of exercise, not only for your immune and muscle heath, but mainly for supplying critical growth factors that allow your brain to heal more quickly. The explainations in the book do for Alzheimer's patients what "The Diabetes Solution" has done for diabetes. It gives you a foundation for understanding the disease and changing your habits to fit your body's needs.

Some of the essential supplements recommended for different people include omega-3 fatty acid supplements, like fish or krill oil, Vitamin E, basic nutrients for brain health, such as Calcium, Magnesium and Vitamin D, Zinc for the immune system and a combination of nutrients that can support healthy neurons - Phosphatidyl choline, Phosphatidyl Serine, L-glutamine, Taurine, Acetyl-L-carnitine and alpha-lipoic-acid. Resveratrol can also be useful. Read the book. It is not simple, but it is pretty complete.

The other book that is similar to this one, but hasn't quite got all the nutrition right is The Alzheimer's Solution by Dean and Ayesha Sherzai. Their philosophy is a little different, but there is an excellent section in the end of the book on brain exercises. Just like muscles, brains can wither away when not in use. You forget words that you don't use, forget how to solve problems you once could - all natural, but just like muscles, you can build back a lot of these abilities with practice. You can't really expect to regain function without practice, so don't forget this very important aspect of recovery.

The final piece of the picture is inflammation. Gut health is directly related to brain health. If you have an infection, you might not always be aware of it. Bladder infections, fungal infections, viral infections can all be subtle affectors of brain and nervous system health. Stomach aches and leaky gut can also affect brain health. That is why it is important to identify and get rid of infection and irritations from allergies, etc. A combination of probiotics and eating fiber-rich, healthy green foods can be helpful in healing the brain and gut. if you decide to use a probiotic, choose a probiotic with a wide range of organisms to replace any possible deficiencies in your gut flora. This can be a path to increase immune tolerance for those with allergies (read about short-chain fatty acids) and increase digestive efficiency. Most people recommend using probiotics daily, but I find that it can be equally effective to take a probiotic weekly over several months. The point is to repopulate your gut with useful bacteria and probiotics are inefficient, since they mostly get killed off in your stomach, so providing repeated doses will increase your likelihood of success. Try to get a probiotic with as many of the following organisms as possible: Lactobacillus (acidophilus, rhamnosus, brevis, plantarum, casei, reuteri, gasseri, fermentum) and Bifidobacterium (lactis, longum, breve, coagulans, infantis). Don't be afraid of probiotics containing Streptococcus thermophilus or salivarius as these are well-known beneficial bacteria used in the fermentation of cheese and yogurt and they produce lactase, which can help digest the lactose in milk. This last bit of advice is personal rather than a direct recommendation from the book, but it makes sense to recruit as many helpers as possible, as long as they don't upset your already well-settled microbial workers. Additionally, I find that a probiotic with 30,000 cfu (colony forming units) is more than adequate and is less likely to upset your stomach than those with more bacteria.

Hope you find this info motivational and increases your interest in reading the book.

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Mrs. S. Pell
Alzheimer's
Reviewed in the United Kingdom on July 19, 2024
Verified Purchase
My Dad has this and I wanted to read up on it . Informative book . Good quality . Interesting read

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Brand Honesty.
Amazing
Reviewed in India on May 21, 2023
Verified Purchase
This is a must have book for every family not just Alzheimer's patients. Recommended, although Indians may find all these things already incorporated in lifestyles since long times..quite likely the reason Alzheimer's as a disease is very rare in India and research into it has just begun with few lucky patients. Please buy right now. Thanks Amazon India.

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Fausto Machado
Começamos a ver luz no fim do túnel
Reviewed in Brazil on March 2, 2018
Verified Purchase
Saber que uma doença mortal e incapacidade tem prevenção e tratamento eficazes é uma grande esperança. Melhor ainda, o modo como é colocado no livro traz autonomia para os que decidem seguir o protocolo do Dr. Bredesen, a maioria das ações são acessíveis, sem medicamentos caros e patenteados, basicamente mudanças em hábitos de vida. Vale a pena ler, se houver casos na família ou se simplesmente quer cuidar de sua saúde, pois é disto que fala o livro.

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Bruno Louie Cordovado
Everyone knows a cancer survivor; no one knows an Alzheimer’s survivor – until now!
Reviewed in Canada on September 25, 2017
Verified Purchase
Dr Bredesen has researched Alzheimer’s for 30 years and has succeeded in unraveling this disease. He can prevent it and in most cases reverse its associated decline. (He has already helped about 200 people.) His discoveries represent a paradigm shift regarding this disease.

First, here is the current view of Alzheimer’s:
-it is a single disease caused by the accumulation of plaques made of amyloid-beta
-to treat it find a way of stopping the plaques from forming or remove them once they have formed
-most drugs developed with this view have succeeded in stopping or removing plaques but the patients either got no better or got worse.

Here is what Alzheimer’s really is:
-it results when the brain responds to various events by downsizing
-there are 3 types of Alzheimer’s and each is a protective response to different triggers (or a combination of triggers):
a) inflammation caused by too much sugar, infections or other causes
b) low levels of synapse supporting nutrients, hormones and other molecules
c) toxic exposure such as metals or bio-toxins
-usually when the brain responds to these triggers it goes on functioning normally
-the problem comes when these triggers are chronic, multiple, unrelenting and intense
-then the process goes haywire and too many of these triggers start the process of brain cells dying

The solution then is to:
a) identify which triggers are present
b) remove the contributors
c) remove the amyloid-beta
d) rebuild the lost synapses.

These triggers (or factors) are about 36 in number so identifying which are present involves doing tests for each. These tests measure a specific condition in the body. Each test must be in a certain range otherwise it adds to the triggers. i.e. for each item that is out of range it contributes to Alzheimer’s. Once the out of range values are identified, changes are made to bring them all to the optimal value. (The optimal value is not just what is considered ‘normal’ but what is best for reversing the Alzheimer’s.) As more and more of these items are corrected, a certain threshold is reached and the person starts to improve. It is like having 36 holes in your roof that are causing a flood and realizing it is not enough to fix one hole, most of the holes need to be fixed to stop the flood. It’s similar with the brain: once the ‘holes’ are found, each is fixed until enough of them are stopped to get to a point where the death of brain cells has been reduced and compensated by the growth of new ones.

With this background in place the major part of the book explains each trigger/factor, how to test for them and how to correct those that are out of range.

Throughout the book there are stories of some of those who were helped.

Many other books are available about Alzheimer’s but they focus on only a few of the 36 factors. For people who have only a few factors out of range, fixing those will help. However, this will not help those who have different factors which are causing their Alzheimer’s. Dr Bredesen’s program is the only one that is comprehensive enough to deal with all possible triggers.

Dr. Bredesen has trained over 450 others in this program so if you or a loved one has Alzheimer’s or is showing signs of cognitive decline, you should be able to find someone who can help. (I emailed him and am waiting to find out if there is anyone in Canada.)

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Francisco Cortez Camacho
Estupendo e informativo
Reviewed in Mexico on September 27, 2017
Verified Purchase
Es un gran libro que nos explica las raíces y causas de esta enfermedad. Proponiendo un enfoque muy distinto a su tratamiento. Lo recomiendo ampliamente

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