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The End of Alzheimer's Paperback – January 1, 2017
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- Publisher : VERMILION (January 1, 2017)
- Language : English
- ISBN-10 : 1785041223
- ISBN-13 : 978-1785041228
- Item Weight : 13.8 ounces
- Dimensions : 6.02 x 0.94 x 9.21 inches
- Best Sellers Rank: #513,051 in Books (See Top 100 in Books)
- Customer Reviews:
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Top reviews from the United States
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I first heard of the Bredesen Protocal last winter, when Maria Shriver discussed it on the Today Show. I quickly researched it as much as possible, but info was limited. I had a feeling a book was forthcoming, so I anxiously awaited it's release. I was worried The End of Alzheimer's would contain too much technical information that I might not be able to understand. I was very happy to see that it was written in a casual format that intentionally makes it easier for the rest of us. The details are clear, the tone is casual, and it's easy to follow.
As I read through this book, I was surprised by how many points were familiar to me. That's me! I do that! Oh heck! It was as enlightening as it was scary. Living with Mom, I also live in fear because I know I'm on the same path she struggles down every day. That's my future.
On page 97, Bredesen says "How to give yourself Alzheimer's. Live your life in a way that keeps your brain supplied with as many as possible of the 36 factors that influence whether APP gets cut into the destructive quartet or the beneficial duo. How to prevent it. Live your life in a way that minimizes the number of the 36 inducing factors in your brain." Those 36 factors are clearly laid out and I believe they are not difficult to control.
Several years ago, I struggled with brain fog and often had difficulty remembering numbers for even a couple of minutes. I also was overweight and had heart problems. I reached a point where I thought I would die, so I wrote my will and made plans for my dogs after I was gone. Then I said enough was enough, and I dramatically changed my lifestyle. I cut out processed foods, ate lots and LOTS of vegetables and fresh fruits, especially leafy greens and berries. I ate wild caught fish, but no other animal products. My diet was low in grains. I used the USDA Super Tracker to make sure that my diet exceeded the RDA for every nutrient they tracked. There's a lot more to it, but I was eating all the time and I exercised every single day. Within a few weeks, I had much more energy. Within a few months, my brain was on FIRE! But then...
I started a new job and everything about my lifestyle and schedule changed. Long story short, I fell back into old habits, abandoned my perfect diet and exercise program, and gradually regained weight. I also started losing clarity and life became more difficult. I recognize that. And I know that I alone can change that.
I'm so very glad to have read the Bredesen Protocol because I know now, more than ever, the importance of getting back on track. I am making a serious effort to change my future. I believe this book can help. I have already marked my calendar and plan to follow up on this review in 3 months and again in six months. Mom may be too far along, I don't know, but it's worth trying for both of us. Dr. Bredesen states in the book that his protocol may not work for frontal lobe and other types of dementias. It has only been tested on Alzheimers. I feel that it's still very important to heed his advice, as Alzheimers often doesn't get a definite diagnosis until after death.
Why is this an important issue? Because we have a tsunami of Alzheimer’s disease approaching on and it is on track to take the lives of 45 million of the 325 million Americans alive today. It’s currently the third leading cause of death in the US and is costing the United States over $220 billion annually. It is a trillion-dollar global health problem. It was the sixth leading cause of death
Dr. Bredesen is uniquely qualified to write this book as he has spent most of his three decades as a physician in this field and was trained at Cal Tech and Johns Hopkins. He is the director of Neurodegenerative Disease Research at the University of California, Los Angeles (UCLA) School of Medicine, He has identified a number of molecular mechanisms at work in this disease, and has created a novel program to treat and reverse it that he calls ReCODE (Reversal of Cognitive Decline)
Many are concerned about this disease and have had themselves tested for the genetic risk factor Apolipoprotein E epsilon 4 (ApoE4). An estimated 75 million Americans have the single allele for ApoE4. Those who are ApoE4 positive have a 30 percent lifetime risk of developing the disease. Approximately 7 million have two copies of the gene, which puts them at a 50 percent lifetime risk.
One of the highlights of the book is his strategy of how to actually reverse ApoE4 damage. This can be done by simply implementing intermittent fasting and restricting your eating window to 4-8 hours a day. This is because ApoE4 appears to be a gene that all ancient humans had and it provided an metabolic advantage for those that were regularly going without food and fasting for periods as was common in ancient times. Individuals that had this gene would actually live longer as they could more easily switch between fat and carb burning. This knowledge can help you actually reverse the damage that most of us acquire when we inherit this gene by merely implementing intermittent fasting.
His ReCode program discussed three dozen different tests that one can screen for and if they are abnormal they can be addressed to improve the synaptic balance to a more healthy level and reverse or radically reduce the risk of Alzheimer’s. If you ever had any concern about Alzheimer’s there is no question in my mind that this is the book to get. Strongly recommended.
Top reviews from other countries
As well as documenting practical approaches to reversing Alzheimer's (and in so doing give hope to the millions who are already afflicted or who are genetically predisposed to the disease) Dr Bredesen explains how underlying physiological pathways converge to increase the risk of getting the disease. Dr Bredesen intersperses his narrative with testimonials of patients who have successfully reversed this truly awful soul-destroying disease.
It is evident that Dr Bredesen has faced huge obstacles in extending the reach of his programme to reverse Alzheimer's however he has been resolute in his determination to conduct further trials and to spread the message of hope that his programme, ReCODE offers to many millions of sufferers and their loved ones.
I remain convinced that Dr Bredesen's 21st Century 'programmatic' medical approach will ultimately gain world-wide acceptance not just for Alzheimer's but for other modern chronic diseases such as obesity, diabetes and cardiovascular disease.
I'd like to say thank you to Dr Bredesen and his team for their research over the past three decades because for people like me who face the horrific prospect of Alzheimer's I now have hope and a means to avoid it and live a healthier lifestyle as I age.
This is brilliantly written and easy to understand. A fantastic resource.