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Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime Hardcover – September 4, 2007
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“(Dr.) de Grey is hardly just another fountain-of-youth huckster. His it-might-work ideas are based on existing, published, peer-reviewed research. He thinks more like an engineer than a scientist. If even one of his proposals works, it could mean years of extended healthy living.” ―Paul Boutin, The Wall Street Journal --This text refers to the Paperback edition.
From the Back Cover
"His clarion call to action is the message neither of a madman nor a bad man, but of a brilliant, beneficent man of goodwill, who wants only for civilization to fulfill the highest hopes he has for its future."
--Dr. Sherwin Nuland, clinical professor of surgery at Yale University School of Medicine and author of How We Die and The Art of Aging
"Seems to me this man could be put in jail with reasonable cause."
--Dr. Martin Raff, emeritus professor of biology at University College London and coauthor of Molecular Biology of the Cell
A leading researcher sketches the real "fountain of youth"
- The most realistic way to combat aging is to rejuvenate the body at the molecular and cellular level, removing accumulated damage and restoring us to a biologically younger state.
- Comprehensive rejuvenation therapies can feasibly postpone age-related frailty and disease indefinitely, greatly extending our lives while eliminating, rather than lengthening, the period of late-life frailty and debilitation.
- A comprehensive panel of rejuvenation therapies could probably be validated in laboratory mice within a decade. We would then have a good chance of developing it for human use only a decade or two thereafter.
- Removing the causes of aging-related deaths will also eliminate all the suffering that aging inflicts on most people in the last years of their lives.
- Aging kills 100,000 people a day: old people, yes, but old people are people too. Social concerns about the effects of defeating aging are legitimate but don't outweigh the merits of saving so many lives and alleviating so much suffering.
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Top customer reviews
personally I will suggest to skip the first part ( that it's just a big intro about ethics etc... but I think we are beyond that) and go directly from the second part where it's the practical part.
I more than recommend this book!
The idea is that unwanted aging is best prevented by identifying and removing cumulative damage, and not trying to figure out exactly which biological mechanisms and processes cause it. Though that might be preferable, it's probably not as attainable.
In essence, cure the disease, not the cause(s) or the symptom(s). Many feel the book devalues the approach of gerontologists. Maybe I'm wrong, but for me it doesn't. It only highlights the fact that gerontology isn't intent on preventing unwanted biological aging in humans. As such, it isn't as pragmatic, effective or realistic an approach to solving that problem. Being interested in aging, and wanting to prevent some aspect of it are, or can be two very different things. And that's fine.
In some sense, the book argues that many conditions that are seen as age-related diseases, are just symptomatic of the larger disease of aging. They're subsets of aging. This seems fairly logical, but I'm not sure to what extent it's accurate. For one thing, it can be hard to differentiate between age- and time-dependent disease. In any case, it definitely has merit as an idea.
The writing style is good, but very conversational. Some further editing might help. This isn't necessarily a bad thing, as it might make the book approachable to a wider audience. So I don't think it suffers too much from that, but I personally would like more clarity and brevity. I would also like some more detail, but that's what the internet is for.
Basically this is a very good introduction for someone who isn't familiar with regenerative medicine. With all the interviews, etc it might feel as if Aubrey de Grey is just echoing himself, but consider his target audience. It's important to keep the message fairly simple, fairly consistent and fairly current. He does that in shovels.
Frankly, if we gave more attention to anti-aging research, we'd be able to move this along quickly and also cure numerous diseases in the process, as well as prevent many others.
I'm almost done with the book. :)
thoughts and approaches towards slowing down the aging process