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Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime Paperback – October 14, 2008
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“(Dr.) de Grey is hardly just another fountain-of-youth huckster. His it-might-work ideas are based on existing, published, peer-reviewed research. He thinks more like an engineer than a scientist. If even one of his proposals works, it could mean years of extended healthy living.” ―Paul Boutin, The Wall Street Journal
From the Back Cover
"His clarion call to action is the message neither of a madman nor a bad man, but of a brilliant, beneficent man of goodwill, who wants only for civilization to fulfill the highest hopes he has for its future."
--Dr. Sherwin Nuland, clinical professor of surgery at Yale University School of Medicine and author of How We Die and The Art of Aging
"Seems to me this man could be put in jail with reasonable cause."
--Dr. Martin Raff, emeritus professor of biology at University College London and coauthor of Molecular Biology of the Cell
A leading researcher sketches the real "fountain of youth"
- The most realistic way to combat aging is to rejuvenate the body at the molecular and cellular level, removing accumulated damage and restoring us to a biologically younger state.
- Comprehensive rejuvenation therapies can feasibly postpone age-related frailty and disease indefinitely, greatly extending our lives while eliminating, rather than lengthening, the period of late-life frailty and debilitation.
- A comprehensive panel of rejuvenation therapies could probably be validated in laboratory mice within a decade. We would then have a good chance of developing it for human use only a decade or two thereafter.
- Removing the causes of aging-related deaths will also eliminate all the suffering that aging inflicts on most people in the last years of their lives.
- Aging kills 100,000 people a day: old people, yes, but old people are people too. Social concerns about the effects of defeating aging are legitimate but don't outweigh the merits of saving so many lives and alleviating so much suffering.
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The next part of the book was the more technical section, which is also the majority of the book. The analogy from that portion was that "repairing aging by repairing cells" was similar to repairing a tire on a car--it does not matter whether a tire was flat from the car running over a nail, the tire tread wearing thin from over use, or any other reason--the cure would still be the same (put a new tire on the car). Putting the "new tire" of "new cells" in a body seemed to be the point of the next series of chapters. However, by the time I passed page 100, I knew I was skimming because the level of unfamiliar technical detail was not particularly attractive to me. For some readers, they will crave the detail. For myself, I stopped reading the book. When my peers or students ask me about a book, I conclude with a recommendation for a book if the book somehow causes me to see the world differently or act differently. I believe that this book might do that for some people. As for myself, I already had a general sense of the science from other journal articles and TED talks, so I stopped reading to examine other interests. The evidence seems quite credible, but the presentation was not appealing to my biased mind.
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thoughts and approaches towards slowing down the aging...Read more