- Paperback: 352 pages
- Publisher: Columbia University Press; Reprint edition (October 1, 2013)
- Language: English
- ISBN-10: 0231161174
- ISBN-13: 978-0231161176
- Product Dimensions: 6.1 x 0.7 x 9 inches
- Shipping Weight: 14.9 ounces (View shipping rates and policies)
- Average Customer Review: 137 customer reviews
- Amazon Best Sellers Rank: #115,379 in Books (See Top 100 in Books)
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The Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance Reprint Edition
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Anyone seriously interested in who we are and how we function should read this book. (Peter Forbes The Guardian)
Nessa Carey takes us on a lively and up-to-date tour of what's known about epigenetic mechanisms and their implications for ageing and cancer. (Laurence Hurst, University of Bath Focus Magazine)
[Nessa Carey's] book combines an easy style with a textbook's thoroughness.... A bold attempt to bring epigenetics to a wide audience. (Jonathan Weitzman Nature)
Carey's report on the rapidly developing state of epigenetics research may help nonscientists with public-policy, investment, and health-care decisions. (Booklist)
An exhilarating exploration of an exciting new field, and a good gift for a bright biologystudent looking for a career choice. (Kirkus Reviews)
An enlightening introduction to what scientists have learned in the past decade about [epigenetics]. (Carl Zimmer The Wall Street Journal)
This book provides an excellent introduction to a fascinating new field that may revolutionize our understanding of human health and disease. Highly recommended. (Library Journal)
A must-read for every intelligent person who likes to know what is going on in modern science. (Graham Storrs New York Journal of Books)
[Carey] provides an excellent and largely accurate account of a fascinating and fast-moving area of modern biology. (Jonathan Hodgkin Times Literary Supplement)
Written in an engaging manner using everyday metaphors to clarify complex concepts and utilizing well–defined diagrams, the author has produced an outstanding book with her wit and expertise. (Rita Hoots NSTA Recommends (National Science Teachers Association))
[A] mercifully clear writer. (Katharine Whittemore The Boston Globe)
The new scientific field, epigenetics, is revolutionizing our understanding of the structure and behavior of biological life on Earth. Epigenetic ideas help explain why mapping an organism's genetic code is simply not enough to determine how it develops or acts, and shows how nurture combines with nature to engineer biological diversity. Surveying some of the key scientific investigations and breakthroughs in this field over the past twenty years, Nessa Carey paints a broad intellectual canvas that readers of science and medicine will find both fascinating and promising. Her book helps us discover how we are much more than the sum of our genetic codes.
Top customer reviews
Similarly, this book introduces the discoveries in epigenetics (epi- meaning "on", or a layer on top of classical genetics) and pretty much all of this will be new information unless you have been actively working in the field of cell biology over the past few years.
The book talks about the paradigm shift that is occurring as cell biologists are realizing that this epigenetic information is as complex and important to the correct function of life as the underlying DNA genome, and even allows for Lamarckian inheritance in certain cases where an offspring's own epigenetic information and phenotype can be influenced by that of the parents, meaning that some environmental effects in a parent's life can directly influence future generations.
Also much of the non-protein-coding genome that for many years was considered to be unimportant "junk" is now turning out to be very important as it can be transcribed into functional RNA molecules that perform important functions. The book contains a simple graphic showing that the ratio of the non-protein-coding DNA to that of traditional protein coding genes increases in direct proportion with the complexity of the organism. The fundamental genes and proteins between say a chimpanzee and a human are virtually identical and it now begins to look as though it's that "junk" DNA that makes all the difference.
This is a fascinating look at recent developments in the ever-accelerating biological revolution and I highly recommend it to everyone who yearns to understand how life works.
Most recent customer reviews
A great service to a non-specialised public.
I began this book with hopes that I would better understand how tags were added to genes that bypassed...Read more