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First Pulse: A Personal Journey in Cancer Research Paperback – December 14, 2001
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...Garnett's work has more fundamental implications for defining the common ground between art and science. -- The Lancet, April 22, 2000. Exploring sci-art: the final frontier, by Kelly Morris.
Merrill Garnett is a true original--a person in pursuit of a profoundly humane goal along career and personal paths quite unlike anyone else I have ever met. Merrill is one of the rare individuals for whom "doing well by doing good" isn't a superficial slogan but rather is truly second nature. In this book Merrill has produced a fascinating, intensely personal account of his 40 year quest for effective cancer treatments.I'm sure most readers will react to the book as I did. I was engaged and captivated--both at the personal and at the scientific levels. In this era of beaurocratized science, people like Merrill are increasingly rare and increasingly important. Readers are treated to a deep, clear look into this world. -- Paul Bingham, Department of Biochemistry & Cell Biology, State University of New York at Stony Brook -- Publisher Comments --This text refers to an out of print or unavailable edition of this title.
From the Publisher
Three years since the publication of the first edition, the 2nd edition of First Pulse is now available. It includes an additional chapter summarizing recent research and developments at Garnett McKeen Laboratory.
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Top Customer Reviews
first, i must name my preconceptions of First Pulse, in what may be due to my own issues of mortality. upon receiving the book, i immediately looked at every of the book's numerous paintings by Joy Garnett. they are images at once ghostly and haunting, and beautiful and sublime, of various stages of cell growth and decay, in vibrant yet subdued colors, as if viewed through a microscope.
this visualization of various stages of cancerous growth and subsequent images of treatment in painted form has the quality of a Francis Bacon painting. the horror of Bacon's Study of Pope Innocent X or Figure with Meat, are somehow aestheticized within the scraping lines of paint which at once blur and etherealize the subject. these same streaking lines are present in Joy Garnett's paintings, and my first reaction was an association of cancer with this Baconian visualization of horror. but, the paintings somehow made the disturbing mystery of cancer into something tangible, aesthetic, and even neutral. somehow, the beautiful painted light which visualizes scientific exploration and understanding portrays that journey itself as an artistic venture.
the paintings illuminate the cancerous cell, and bring the science of an esoteric and highly specialized field of research into a public domain, where it should be.
i would not have thought this to be true, but after reading the words of Dr. Garnett alongside the painted images of his daughter, i am left with a sense of awe at what First Pulse could represent- a new model of treating cancerous cells, based on electrical knowledge.
Dr. Garnett took a different path for his research and experimentation. his dedication to understanding cancer centered around a belief that the model of killing off cancerous cells with toxic treatment was one model, and that there could be another model, based on the metabolism of energy in a cell. instead of destroying the cell, the treatment could restore the vitality of the cancerous cell.
Dr. Garnett's search was on for finding such a treatment...
only another electrochemical scientist could say what kind of personal journey it would be to have created and tested 30,000 chemical compounds in this search. but somehow, the quest for truth allows for such determination and belief. and it was the belief about this new 'electrogenetic' model of medicine which would ultimately prove rewarding.
Dr. Garnett knew intuitively that there was a vital "pulse" in the cell, which was absent when the cell died away. to explore this dimension was to explore the question of life itself: that is, what makes something alive. in the technical language of medicine, the conclusion centered around the concept of electron transfer, which is another specialized name for general electrical phenomenon that exists in between the microcosm and macrocosm of the universe.
in fact, this electronic interaction _is_ the First Pulse that Dr. Garnett believes constitutes life. that is, along with the structural information in a chain of molecules, say, making up DNA, is a flow of energy which keeps the cell, and thus the body, healthy. this pulse is a vibration, the result of a frequency of shaking molecules, a literal 'music of the spheres' to be heard by those listening to its signal.
ultimately, this electronic First Pulse is metabolic: ~the cell's food is electrical~ which in turn the DNA utilizes to create an electrical field. filling in a piece of the mysterious puzzle of electrical evolution, Dr. Garnett states: "The schematic is complete. The cell has its first pulse, which makes an active energy exchange between the internal and external... And this first pulse resonates with many other cells, and the packed cells carry on their pulsations with the environment. They resonate with each other and set each other off by inductive influence so that their pulses increase. And the tissue pulses appear, and the heart beats and the brain discharges and the muscles evolve. The organelles modulate and use this in contractile structures, converting the pulse to organic phosphates and other high-energy bonds. But the cell pulse is first and provides the raw electrical energy for all the physiologic pulses."
thus, the cosmologists belief that the universe evolved out of electromagnetic radiation and the birth of electrically charged particles, creating matter in the void, now, there is an electrical theory of life, constituted on the knowledge of electricity at the molecular level up to the human being. it is an important accomplishment for this field of electrical research, and specifically so for the medical field.
this is because Dr. Garnett's research work, grounded in the pragmatics of trial and error scientific (and artistic) experimentation, led to a treatment called the palladium complex (LAPd), based on this new electrogenetic understanding of cancer, restoring the cells energy instead of killing the cancerous cells off, as in traditional chemotherapy treatment. this unique approach to cancer treatment was the result of an investigation into corrosion engineering and the electrical properties of metals. in the end, Dr. Garnett's hard work and vision have produced a new model for cancer research, and the LAPd complex is in the testing stage, after having restored laboratory mice from full-blown cancer to full health.
in all, the work of Dr. Garnett, and the visualization of this miraculous revitalization of a cell's energy flow via the LAPd complex by his daughter Joy Garnett, is a victory for the fields of both the science and art of living. my congratulations go to them in their vital and public journey.
Dr. Garnett writes clearly and simply, without fanfare or emotionalism. He invites the lay reader into an amazing world without dumbing down the material. His style is wonderfully conversational and inspiring, with just enough detail of the various technical aspects of the material, not so much as to overwhelm the lay reader, but enough to provide the trained scientist an overview of the route he traveled and the never-wavering inspiration for his research.
Of course what makes this book so exciting is the clinical results from his initial supplement, polyMVA, which has been approved by the FDA and is in distribution. The results from clinical applications by licensed practitioners are impressive if still in the first stages. While it is certainly a first step, to be followed by further refinements, and especially to be studied as used in combination with other therapies, both conventional and integrative, Garnett has taken a bold and innovative step beyond the standard scientific approach to treating metabolic diseases and cancer.