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Frameshift Paperback – November 1, 2005
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Geneticist Pierre Tardivel may not have long to live―he's got a fifty-fifty chance of having the gene for Huntington's disease. But if his DNA is tragic, his girlfriend's is astonishing: Molly Bond has a mutation that gives her telepathy. Both of them have attracted the interest of Pierre's boss, Dr. Burian Klimus, a senior researcher in the Human Genome Project who just might be hiding a horrific past. Avi Meyer, a dogged Nazi hunter, thinks Klimus was the monstrous "Ivan the Terrible" of the Treblinka Death Camp. As Pierre races against the ticking clock of his own DNA to make a world-changing scientific breakthrough, Avi also races against time to bring Klimus to justice before the last survivors of Treblinka pass away.
Winner of the Seiun Award―Japan's top honor in science fiction―and a finalist for the Hugo Award, Frameshift is classic Robert J. Sawyer, combining a heart-wrenching human story and cutting-edge science into a pulse-pounding thriller that "delivers the real thing with subtlety and great skill" (Toronto Star).
- Print length352 pages
- LanguageEnglish
- PublisherTor Books
- Publication dateNovember 1, 2005
- Dimensions5.5 x 0.78 x 8.5 inches
- ISBN-100765313162
- ISBN-13978-0765313164
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Editorial Reviews
Review
“Filled to bursting with ideas, characters, and incidents.” ―The New York Times
“You hardly need me to tell you to buy his latest, Frameshift. You know it's good, you know he gets the techy bits right, and you know he's interesting and thought-provoking.” ―Analog
“Robert Sawyer's science fiction is always ambitious, well-written, and imaginative. With each novel he keeps getting better.” ―Kevin J. Anderson
“Sawyer has created a gripping medical sf thriller...Highly recommended.” ―Library Journal
About the Author
Robert J. Sawyer is the Hugo Award-winning author of Hominids, the Nebula Award-winning author of The Terminal Experiment, and the Aurora Award-winning author of FlashForward, basis for the ABC TV series. He is also the author of Calculating God, Mindscan, the WWW series―Wake, Watch and Wonder―and many other books. He was born in Ottawa and lives in Toronto.
Product details
- Publisher : Tor Books; 1st edition (November 1, 2005)
- Language : English
- Paperback : 352 pages
- ISBN-10 : 0765313162
- ISBN-13 : 978-0765313164
- Item Weight : 12.6 ounces
- Dimensions : 5.5 x 0.78 x 8.5 inches
- Customer Reviews:
About the author

Robert J. Sawyer is one of only eight writers ever to win all three of the world’s top awards for best science-fiction novel of the year: the Hugo, the Nebula, and the John W. Campbell Memorial Award. He has also won the Robert A. Heinlein Award, the Edward E. Smith Memorial Award, and the Hal Clement Memorial Award; the top SF awards in China, Japan, France, and Spain; and a record-setting sixteen Canadian Science Fiction and Fantasy Awards (“Auroras”).
Rob’s novel FlashForward was the basis for the ABC TV series of the same name, and he was a scriptwriter for that program. He also scripted the two-part finale for the popular web series Star Trek Continues.
He is a Member of the Order of Canada, the highest honor bestowed by the Canadian government, as well as the Order of Ontario, the highest honor given by his home province; he was also one of the initial inductees into the Canadian Science Fiction and Fantasy Hall of Fame.
Rob lives just outside Toronto.His website and blog are at sfwriter.com, and on Facebook, Twitter, and Patreon he’s RobertJSawyer.
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Top reviews
Top reviews from the United States
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I really enjoyed the book as I have all Robert Sawyer books. I have no idea if the DNA and genetics information presented within are correct or not, but the positions taken made sense. This is a good old science fiction story, kinda pulpy and a very easy read, despite its length.
The book has a message in that we should treated equally and not be discriminated on based on the content of our genes. I believe that author is correct in his message and viewpoint. I am not sure of the current laws regarding genetic discrimination.
On the other hand, the mysterious ability to read other people's minds is, in my opinion, a greatly over-worked scifi gimick. Also, the greedy corporation that will sink to any depths to enrich itself is an overdone cliche. The notion that a business should bankrupt itself on behalf of a tiny minority of incurable people is as ridiculous as the idea that a company would murder such people. Further, the spectre of a neanderthal child being raised like an ordinary child struck me as silly. Emotionally appealing, but silly. Finally, the "DIEHARD" (think Bruce Willis) climax was predictable and tired.
FRAMESHIFT was OK, but I would have liked it better if Sawyer hadn't cluttered it up with so many sub-plots. He should also have tried harder to resist the temptation to use his story as his own personal little soapbox. I don't know about you, but I read this stuff to be entertained, not to give some writer a platform to preach to me. From my perspective, it's a mediocre three stars. Proceed at your own risk.
Racism, Nazis, suspense, a bit of romance, it's all here, as well as the science that explains DNA and it's place in genetics. It was just well enough explained to add to the story, not distract from it. I wholeheartedly recommend this book to suspense readers everywhere.
Robert B. Gordon
This is the first Robert Sawyer novel that I have read, and I enjoy his prose and story telling style. The characters are well developed. There is a sufficient amount of tension in the story, and there is a decent mystery component to it. There were some flaws in the novel. I thought the genetics described in the book was a little more detailed than it needed to be. The beginning of the story jumps in time back and forth and was hard to follow. The story went a little too heavy into conspiracies, and in particular, the one involving the insurance company made me groan. That being said, this was a well written and enjoyable story that I would recommend.
Carl Alves - author of Blood Street
Top reviews from other countries
それでも,国民自身で民間の保険会社と保健契約を締結しなければ,その高額な医療費を支払えず,貧しい人々は病気になっても病院に行けないという,アメリカにおける保険制度の問題点を浮きぼりにしており,そこを本書は物語にうまくとけ込ませることに成功しています。
健康保険に加入することで,自身の医療費の一部を負担するだけでよいという現状があたりまえの,カナダ人であるソウヤーや,社会保障に力を入れる日本人にとっては,アメリカの保険制度のあり方は,力のある政治家が変えようとしてもなかなか変わらないことが不思議です。どうやらアメリカは極端なまでの民主主義国家で個人を尊重する社会のため,社会主義的な制度にはアレルギー反応を示すようです。
また,本書の大きなテーマの一つはDNAです。
本書タイトルのフレームシフトとは,「フレームシフト突然変異」という生物学用語を指します。
遺伝子の一つであるヌクレオチドが挿入されたり欠損したりすることで遺伝コードが変わってしまうことをいうらしい。
本書では,主人公自身が親から引き継いだ遺伝病だけに限らず,その妻が持つ特殊な能力についてもこのフレームシフト突然変異によって解明しようとしている点が面白い。
物語が進むにつれて,これが前述のアメリカにおける保険制度と絡んできます。
更に,人間ドラマとして,親子の心の繋がりについて,たとえそれが生物学的な親と子でなくてもDNAとは関係なく成り立つ家族関係についてもふれられています。
「神は生命の進む方向についておおざっぱな計画をたてたが,すべてが動き出した後は,定められた進路に沿ってわたしたちが独自に成長し発展していくのをじっと見守っている。」
科学の進歩によりDNAを発見した我々にとって,人間はDNAによって生まれながら運命が定められているように見えてしまいがちだが,実はそこまでは神によるおおざっぱな計画であって,その後の発展や人類の未来は,我々自身の考え方次第なのです。


