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Customer reviews

2.6 out of 5 stars

on September 9, 2015
Laird and Lange is a compelling book on first glance: it covers genetic linkage and association analysis in a sufficiently short and focused book that a working professional could hope to read it cover to cover in a reasonable amount of time.

Unfortunately, it is sloppy and full of errors. It targets a person with a pretty high level of previous statistics knowledge, but even so, inconsistencies in notation are sufficiently ubiquitous that it makes the presentation and derivations hard to follow. Ambiguous symbols are everywhere. Clear errors abound as well; data quoted in case studies change from table to table (compare Table 3.1 and Box 3.5), and some statements fail very basic consistency checks (note Figure 4.1, which shows dominant and recessive recurrence risk ratios having identical scaling on a log-log plot while the preceding derivation shows the ratios having different scaling). After reading about 30% of the book, I began the search for a better text.

The book resembles the LaTeX rough drafts that grad students sometimes hand me; the problem is that in this relationship, I am the student, and I'm not even allowed to ask questions and push the authors to fix them.
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on July 3, 2016
Many mathematical formulas and equations are missing from the text. In some places, the text is accidentally repeated. Overall, the Kindle edition is low quality.
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on February 4, 2012
The book provides great fundamentals for genetic analysis. Although I have not completed the entire book I find that there are few worked out examples in the chapters making the exercises in the back of the chapters difficult to perform given the information in that or previous chapters. Would be great to have answers available (even for odd exercises) to facilitate self learning.
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