Guide to Analysis of DNA Microarray Data, Second Edition 2nd Edition

by Steen Knudsen (Author)

7 customer reviews

ISBN-13: 978-0471656043

ISBN-10: 0471656046

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Written for biologists and medical researchers who don't have any special training in data analysis and statistics, Guide to Analysis of DNA Microarray Data, Second Edition begins where DNA array equipment leaves off: the image produced by the microarray. The text deals with the questions that arise starting at this point, providing an introduction to microarray technology, then moving on to image analysis, data analysis, cluster analysis, and beyond.
With all chapters rewritten, updated, and expanded to include the latest generation of technology and methods, Guide to Analysis of DNA Microarray Data, Second Edition offers practitioners reliable information using concrete examples and a clear, comprehensible style. This Second Edition features entirely new chapters on:
* Image analysis
* Experiment design
* Automated analysis, integrated analysis, and systems biology
* Interpretation of results
Intended for readers seeking practical applications, this text covers a broad spectrum of proven approaches in this rapidly growing technology. Additional features include further reading suggestions for each chapter, as well as a thorough review of available analysis software.

Guide to Analysis of DNA Microarray Data, Second Edition

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Editorial Reviews

Review

"Bioinformaticians, statisticians, computer scientists, biologists, and medical researchers will find this well written book extremely useful." (Journal of Statistical Computation and Simulation, September 2005)

"...useful for anybody who wants to catch up with the marvels of modern laboratory technology..." (Chemistry & Industry, 17th January 2005)

"This book would be useful for anyone working with the DNA microarray technology." (Annals of Biomedical Engineering, November 2004)

"...concisely written with clear illustrations and tables [with]...a good deal of new material." (E-STREAMS, November 2004)

Review

"...provides a great introduction and overview of the computational methods associated with the anaylsis of microarray and chip data." - Gary Hardiman, Ph.D., Division of Biology, University of California San Diego, La Jolla, California --This text refers to an out of print or unavailable edition of this title.

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Product details

Paperback: 192 pages
Publisher: Wiley-Liss; 2 edition (March 2, 2004)
Language: English
ISBN-10: 0471656046
ISBN-13: 978-0471656043
Product Dimensions: 6.1 x 0.4 x 9.2 inches
Shipping Weight: 9.1 ounces (View shipping rates and policies)
Average Customer Review: 4.0 out of 5 stars See all reviews (7 customer reviews)
Amazon Best Sellers Rank: #4,272,280 in Books (See Top 100 in Books)
- #1013 in Books > Computers & Technology > Computer Science > Bioinformatics
- #3400 in Books > Science & Math > Biological Sciences > Biology > Molecular Biology
- #4589 in Books > Medical Books > Basic Sciences > Genetics

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Customer reviews

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Top customer reviews

This is the best short intro to DNA microarray analysis

ByRonald Tayloron July 15, 2002

Format: Hardcover

This is the best short introduction that I've seen to DNA
microarray analysis - and our lab has just about every
computational biology book ever published. (We are the core
array analysis facility at the U of Colorado School of Medicine,
operating downstream of one of the largest single Affymetrix
facilities in academia.)
This book is clear, accurate, and concise - I'm very
enthusiastic about it. I've recommended it to everyone in
our lab, and to our collaborators. I have even xeroxed the
analysis flow chart in fig 2.1, annotated it a bit, and
taped it on our lab door. I found something I really liked
on just about every other page. One example: the comparison
between Euclidean and Pearson correlation distance on pp.
45-46 is the best short explanation I have ever seen.
Chapter 2 on basic data analysis is superb (it even manages
to describe the Multiple Testing problem in its limited
number of pages), and the chapters on investigating
regulatory nets and molecular classifiers give you a wonderful
taste of some cutting-edge stuff within their length constraints.
All the chapters are excellent. Biblio is very current. Price
is a little steep ... for ~150 pages, but it's a great
little book. 5 stars.

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an easy read -- a cookbook

ByA customeron January 22, 2004

Format: Hardcover

True to its stated purpose: best used as a roadmap by mathematically unsophisticated newcomers to analysis of microarray data. Somewhat superficial, and it becomes more so in later chapters. Does not explore harder issues in detail. Does not touch upon future directions of the technology. Its advocacy of the Unix awk program is anachronistic; tellingly, the reference cited for awk is from 1988. Not a groundbreaking book, just solid practical advice.

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just an introductory

ByA customeron May 11, 2003

Format: Hardcover

If you just want an general idea of how the microarray and analysis works so you can understand other people's data and method. And you willing to pay 40 bucks for 125 pages(including index) instead of search free resources online. This will be the book for you.
If you want to do array analysis your self. try other books.

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"A Fine Introduction to DNA Microarray Analysis"

ByA customeron April 22, 2003

Format: Hardcover

"...a fine introduction to DNA microarray analysis using good concrete examples, well reasoned descriptions...and much-needed examination of the tools, technologies, and research resources...after reading this book, anyone new to microarray data should understand what can...be measured..." (Nature Genetics, Vol. 33, March 2003)

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no title

ByA customeron October 14, 2002

Format: Hardcover

"This book is really not worth your money--it is a very simplistic and not up-to-date treatment of DNA microarrays. The field is progressing fast and, with less than 150 pages, this early book is already obsolete. Presentation of statistical methods is quite weak."

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Useful Book

ByA customeron June 20, 2003

Format: Hardcover

"...This useful little book .... I'd recommend anyone setting out to use this methodology to buy a copy for the lab." (British Society for Developmental Biology Newsletter)

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Recommended Book

ByA customeron May 28, 2003

Format: Hardcover

"...I'd recommend anyone setting out to use this methodology to buy a copy for the lab." (British Society for Cell Biology Newsletter)

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