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Holistic Health Perque Activated B-12 Guard (2000 Mcg, 100 Lozenges)

4.6 out of 5 stars 51 customer reviews
| 7 answered questions
About the Product
  • Optimal B-12 delivery to the brain
  • Provides nearly the same B-12 uptake as from injection
  • Promotes hearth health and fights fatigue
  • Perque Activated B-12 Guard is in lozenge form for maximum uptake and optimal delivery to the brain. Studies on Perque Activated B-12 Guard lozenge formulation show nearly the same B-12 uptake as from injection. Patients notice that they feel better more quickly.*

Frequently Bought Together

  • Holistic Health Perque Activated B-12 Guard (2000 Mcg, 100 Lozenges)
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Total price: $55.92
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Product Description

Size: 100 Lozenges

Vitamin B-12 in our food supply is estimated to be 78% less than in the 1960s. Diet alone is hard pressed to provide the necessary levels of this important nutrient. In addition, stress and reduced hydrochloric acid (HCl) and intrinsic factor production in the stomach impair absorption. The most commonly used forms of B-12 require activation in the body, making uptake quite low - rarely more than 50%.* Perque delivers vitamin B-12 in its superior, activated hydroxocobalamin form. Hydroxocobalamin lasts longer and raises B-12 blood concentrations higher than other forms. Hydroxocobalamin requires no intrinsic factor and is taken up directly by mucous membranes regardless of digestive competence.* Hydroxocobalamin is easily converted to active but short-lived methylcobalamin and adenosylcobalamin as needed in the body. Hydroxocobalamin, the parent to other B-12 forms, provides better, long-lived B-12 action in the body. Perque Activated B-12 Guard is one of the supplements included in the Simplified Methylation Protocol for chronic fatigue syndrome (ME/CFS) and fibromyalgia that was developed by Drs. Neil Nathan, MD; Rich Van Konynenburg, PhD; Amy Yasko, PhD; and Jacob Teitelbaum, MD. This group of supplements ( FolaPro , ActiFolate , Perque Activated B-12 Guard, and Neurological Health Formula ) has been selected and formulated to provide nutrients that the body needs to support normal methylation - a process that is critical for a host of the body's most important chemical reactions, from creation of glutathione (the body's 'master' antioxidant and detoxifier) to energy generation, DNA repair, and serotonin production. See " A Simplified Methylation Protocol is Effective for the Treatment of Chronic Fatigue Syndrome and Fibromyalgia " by Neil Nathan, MD.

Product Details

Size: 100 Lozenges
  • Shipping Weight: 0.8 ounces (View shipping rates and policies)
  • ASIN: B006UKGDOQ
  • UPC: 884915350517 885574173943 784922344625 791760028006 701574974932 882801804946
  • Average Customer Review: 4.6 out of 5 stars  See all reviews (51 customer reviews)
  • Amazon Best Sellers Rank: #13,904 in Health & Personal Care (See Top 100 in Health & Personal Care)
  • Product Warranty: For warranty information about this product, please click here

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Customer Questions & Answers

Customer Reviews

Top Customer Reviews

Size: 100 Lozenges Verified Purchase
My husband and I have MTHFR mutations and he is heterozygous for COMT, while I am homozygous for COMT. This means we do not tolerate methylated products well. This product is hydroxycobalamin, and is therefore well tolerated by most people. 2000 mcg is not likely to be problematic for the majority of people, and is a good start to getting in a form of B12 for those with MTHFR mutations, particularly if COMT mutations are also present. If you don't understand the aconyms, you may want to have genetic testing done through 23andme and look at snpedia for explanations of the results. Doing so will enable you to take control of your health and stop issues such as fibromyalgia, IBS and chronic fatigue syndrome that are often caused by MTHFR mutations and other related snp's such as COMT and CBS.
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Size: 100 Lozenges Verified Purchase
I have been taking this b12 for a few days and each day, I have had more gut distress. Today, I read the inactive igredients. Mannitol is the first and there are 295mg in each pill. If you have problems with mannitol, be warned,
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Size: 100 Lozenges Verified Purchase
While this is probably the most expensive pill source of B12....it worked to raise my blood B12 level from under 200 to over 1,000 in less than 6 weeks. I felt immediate benefits and was surprised. This particular pill is very small, tastes good...if a little sweet...and dissolves quickly. My research and experience leads me to believe that taking this form of B12 is just as effective for me as taking expensive B12 shots. I have tried an alternative, mid-priced form (methylcobalamin) and did not like the way they felt in my mouth...kind of grainy, very slow dissolving.
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Size: 100 Lozenges Verified Purchase
This is probably the form of B12 that is the most pleasant to take.

There are 4 types of B12:

cyano, methyl, adenosyl and hydroxo

The rarest in tablet form is hydroxo-B12 (although it is probably the most common in the body?).

2mg is a fairly decent dose for B12... although you can get 5 mg in the methyl form.

B12 is good for energy... so if you need to fire up the metabolism this is a useful vitamin to take.

If you want to know more about B12 Pacholok's book

"Could it be B12"

is a good read... although she does not clearly differentiate between the different forms.

B12 is an antidote for cyanide poisoning (it removes cyanide from the body)...
and presumably it helps detoxify the body when you get too much of it in the diet.

Thus it is surprising to find that every cheap B12 is the cyanide form (already loaded with cyanide).
Thus it will not remove cyanide from the body... and in fact adds it.

Does cyano-B12 (the B12 in most multi-vitamins) make you feel unwell?
Does your hair start to fall out?
The cyano form affects at least some of us unpleasantly.

Why are we low in B12?
As you get older your stomach acid commonly drops... which results in low B12 levels.

Certain medications like laughing gas can result in low B12 levels too (wonder why your dentist doesn't mention this as a side-effect?).

A surprising number of people are deficient in this vitamin:
It is a possible cause of psychosis and chronic fatigue like symptoms.

This is a quick pick-me-up in a bottle... and a simple way to check if you're a bit low.

If only this B12 wasn't so expensive.

A lot of authors insist B12 is not available in the hydroxo form so I had to try it:

It's a nice experience.

Save them for a rainy day?

:-)
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Size: 100 Lozenges Verified Purchase
If u suffer from Chronic fatigue syndrome or don't wish to have B12 injections this product will be of enormous benefit.
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By Juku on February 10, 2013
Size: 100 Lozenges Verified Purchase
I used to take B-12 shots, but felt I needed to be careful with them. So now, I take one or two of these capsules per day and it definitely puts me more in focus.
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Size: 100 Lozenges Verified Purchase
My B vitamins were too low and upon taking Activated B-12, because it is sub-lingual and goes directly to the blood stream, my blood work readings shot way up! That's a good thing! I now take it, rather than daily, twice a week.
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Size: 100 Lozenges Verified Purchase
I've done some research looking for hydroxy b12 and I think this brand has the best price. It also tastes good.
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