- Paperback: 368 pages
- Publisher: Gallery Books; Reprint edition (January 5, 2016)
- Language: English
- ISBN-10: 1476717796
- ISBN-13: 978-1476717791
- Product Dimensions: 5.3 x 0.9 x 8.2 inches
- Shipping Weight: 12.6 ounces (View shipping rates and policies)
- Average Customer Review: 1,147 customer reviews
- Amazon Best Sellers Rank: #22,419 in Books (See Top 100 in Books)
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Inside the O'Briens: A Novel Paperback – January 5, 2016
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"This heartbreaking book tells the whole story of how a major illness affects a family. Genova’s gift is to show that things do work out, in a sense. Her very human novel teaches us to keep living, to lean on each other and be there to be leaned on.” (Matthew Thomas, New York Times bestselling author of WE ARE NOT OURSELVES)
"This novel of siblings rocked by their father's Huntington's disease is a total tearjerker, but ultimately it's a tribute to family love." (Glamour)
"An intimate, heartbreaking look at life with Huntington's disease." (Marie Claire)
"Genova...compassionately details how an illness—this time Huntington's disease—can destroy not only the afflicted, but those who love them as well." (People Magazine)
“An unsparing, heart-piercing portrait…compelling.” (The Washington Post)
"A moving drama." (US Weekly)
"A gut-wrenching and memorable read." (Library Journal, Starred Review)
"Compelling and masterful." (NYJOURNALOFBOOKS.com)
"Inside the O'Briens is...about resilience and hope." (Bookreporter.com)
“Genova’s book will move readers as well as demystify a condition sometimes called ‘the cruelest disease known to man.’” (Publishers Weekly)
About the Author
Acclaimed as the Oliver Sacks of fiction and the Michael Crichton of brain science, Lisa Genova is the New York Times bestselling author of Still Alice, Left Neglected, Love Anthony, and Inside the O’Briens. Still Alice was adapted into an Oscar-winning film starring Julianne Moore, Alec Baldwin, and Kristen Stewart. Lisa graduated valedictorian from Bates College with a degree in biopsychology and holds a PhD in neuroscience from Harvard University. She travels worldwide speaking about the neurological diseases she writes about and has appeared on The Dr. Oz Show, Today, PBS NewsHour, CNN, and NPR. Her TED talk, What You Can Do To Prevent Alzheimer's, has been viewed over 2 million times.
Top customer reviews
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I moved to California last year and my new neurologist eventually said I might have Huntington's and I got a DNA blood test. (41 CAG repeats in HD language.)
I knew nothing about "prodone" until I read Lisa's book. It explained a lot about my entire adult life and gave me an invaluable new perspective on my mother's "mental illness's."
I'm actually relieved with this diagnosis because I finally have answers as to why I'm like I am.
I have found a great local support group and am also getting on a list for any future clinical trials. I live by myself with my dog. I can still take care of myself and am able to drive. I figure I have at least 5 to 10 years minimum and totally optimistic that there will be drugs developed in my lifetime that will slow or halt the progression of this awful disease. And maybe even a cure.
I am so grateful to Lisa Genova for writing this book and the serendipitous way it appeared the week I needed it most.
Would you want to take a test to tell you your future? Each of the four offspring struggles and decides.
One can feel nothing but compassion for this Irish Catholic family who have worked hard and have a dreadful future. This disease, like many others, is truly unfair. I particularly became attached to Joe during the story, and literally held my breath while watching the disease take over, but not destroy, his life.
Genova again has written a thoroughly excellent book . It will stay with me. The disease, though, must expunged!
Lisa Genova tells us about Joe O'Brien, a Boston policeman, who lives in the Charlestown area of Boston. He is married and still very much in love with his wife, Rosie. They are an Irish Catholic family with four children. There is JJ who is married and expecting his first child. Then there is Patrick who is the owner of a local pub. Meghan is a promising dancer. Finally there is Katie who is a yoga instructor.
Joe has been having problems with concentrating while writing his reports at the end of his shift at work. He is also experiencing uncontrollable muscle spasms and body movements. When he is finally diagnosed with Huntington's and told it is genetic he is devastated.
Lisa relates how each member of the family reacts to this news. How it is affecting their father and how it may affect each one of them in the future.
This is such a heart wrenching story as only Lisa Genova can tell. You will feel everything that the O'Brien's are dealing with. But it is their love and respect for each other that is the glue that helps them navigate this difficult road.
I never hesitate to pick up a book by Lisa Genova. Right from the first page you are all in. This is a book that you will be thinking about long after you have turned the last page.
Lisa Genova did an excellent job making it interesting, easy to understand biologically and covering the devastating aspect with financial security or monetary rape if the male has it. This disease is mainly is seen at the age of 30-45. You have 10-15 years when symptoms project to live. It is a dominant gene and if your mother/ father had it, you have a 50-50 chance of having it. Sadly, their is no cure and it messes with your head more than your body in the beginning.
It is called the most tortuous disease to a person and its very destructive. You can't hold babies, you break glass, you tap dance and don't know it.
Why not 5, I did not like the way she left you hanging in the end. It seemed incomplete with how much she wrote about this character having, not having it. It seemed very Hollywood. Didn't care for it. But I do enjoy Lisa Genova' s angle to use neuroscience as a way to educate the literary world to stop and help fund this disease.
Also, the swearing was worse than an episode of the Osborne' s. Irish don't swear that much. I know Boston. It's a great city. Cop or not. They don't use that language as if it was a poor section. Also, they are religious and devout people who love life and a good time.