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Jarrow Formulas Artichoke 500, Supports Liver and Cholesterol Metabolism, 500 mg, 180 Caps

4.6 out of 5 stars 1,193 ratings
Amazon's Choice highlights highly rated, well-priced products available to ship immediately.
Amazon's Choice in Artichoke Herbal Supplements by Jarrow Formulas

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Brand Jarrow Formulas
Ingredients Artichoke Extract (Cynara scolymus) (leaf) (5% total caffeoylquinic acids), Cellulose, maltodextrin, silicon dioxide, magnesium stearate (vegetable source) and silicon dioxide. Capsule consists of gelatin. See more
Item Weight 0.21 Pounds
Dosage Form Capsule
Allergen Information Gluten Free, Soy Free, Dairy Free, Egg Free, Wheat Free, Fish Free

About this item

  • Country of origin is United States
  • Liver Function – Protects glutathione levels.* Stimulates liver activity by promoting circulation within the liver.*
  • Digestion – Stimulates synthesis of bile, a product of the liver that supports detoxification and the absorption of fat-soluble nutrients.*
  • Cardiovascular Function – Inhibits oxidation of LDL cholesterol and helps maintain healthful levels of HDL (protective) cholesterol already within normal range.*
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
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Product description

Originating in the Mediterranean region, the artichoke (Cynara cardunculus var. scolymus) is now cultivated around the globe. The botanical name is derived partly from the tradition of using ashes (Latin: cineris) as fertilizer and partly from the Greek skolymos, meaning ‘‘thistle’’. The immature buds of the plant consist of the edible bracts (commonly called leaves), which compose the “heart” and surround the immature florets, commonly called the “choke. ” The globe artichoke has been highlighted in traditional-medicine philosophies as a promoter of digestion and a supporter of liver and gallbladder function.* It is known to contain a wide array of bioactive components including luteolin, cynaroside (luteolin-7-O-glucoside), apigenin, inulin, and the caffeoylquinic acids such as chlorogenic acid and cynarin. In fact, many signs point to artichoke’s health benefits resulting from the confluence of many actives rather than the effects of just one. Modern biomedical science continues to decipher artichoke wisdom in many areas of health such as liver support, bile production, and cardiovascular strength.*


Distinguishing Features:

  • Standardized to 5% caffeoylquinic acids
  • 500 mg of leaf extract per capsule

Artichoke is commonly touted as a stimulator of bile production. And according to in vitro studies using rat liver tissue and hepatocytes, artichoke leaf extract does indeed support bile flow.* In animals, artichoke leaf extract has been found to support the production of bile acids and to aid in the digestion of lipids.* Bile is integral to digestion and the metabolic action of bile on cholesterol metabolism has been suggested to be the possible rational for the use of bile in ameliorating occasional digestive complaints.* Yet bile production occurs in the liver so it may not be a surprise that the liver is often broadly mentioned as a beneficiary of artichoke’s effects.

The action of artichoke on the liver begins with bile, but it certainly doesn’t end there. Artichoke extracts help to protect the liver from various toxic assaults such as peroxides and carbon tetrachloride.* Artichoke’s benefits on liver are often attributed to the antioxidant activity of the caffeoylquinic acid phenolic compounds and flavonoids such as luteolin and apigenin. In vitro and in vivo studies have confirmed an antioxidant-related mechanism of protection.* Artichoke extract appears to be able to bulwark glutathione levels in the liver, when exposed to oxidative stress.* Downstream, glutathione depletion often leads to the increased peroxidation of lipids, including LDL.

Artery Integrity

As mentioned above, artichoke can stimulate bile production, which is critical to cholesterol metabolism and excretion.* However, it appears that the benefits of artichoke extend past that of mere bile stimulator. Aside from well-known antioxidants, like chlorogenic acid (a. k.a. 3-O-caffeoylquinic acid), artichoke also contains the flavonoid luteolin. There is accumulating evidence that artichoke’s effects on cholesterol health may be due to luteolin.* Nonetheless, there is solid data demonstrating chlorogenic acid’s role in lipid metabolism too.

Other research suggests that artichoke leaf extract may exhibit support to cardiovascular function via regulation of the endothelial nitric oxide synthase (eNOS) gene.* This gene is involved in the production of nitric oxide and is intimately related to the health of blood vessels and their durability.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Product details

  • Customer Reviews:
    4.6 out of 5 stars 1,193 ratings

Important information

Safety Information

NOT to be used by individuals who are allergic to artichoke, pregnant or lactating. Individuals with gall bladder or bile duct blockages should not use artichoke extract. Keep out of the reach of children. . This product is labelled to United States standards and may differ from similar products sold elsewhere in its ingredients, labeling and allergen warnings

Indications

Supports Liver and Cholesterol Metabolism* Artichoke 500 Extract is standardized to contain 5% total caffeoylquinic acids. Clinical research has documented the following beneficial properties of artichoke extract: • Liver Function – Protects glutathione levels.* Stimulates liver activity by promoting circulation within the liver.* • Cardiovascular Function – Inhibits oxidation of LDL cholesterol and increases healthful levels of HDL (protective) cholesterol.* • Digestion – Stimulates synthesis of bile, a product of the liver that supports detoxification and the absorption of fat-soluble nutrients.*

Ingredients

Artichoke Extract (Cynara scolymus) (leaf) (5% total caffeoylquinic acids), Cellulose, maltodextrin, silicon dioxide, magnesium stearate (vegetable source) and silicon dioxide. Capsule consists of gelatin.

Directions

Take 1 capsule per day with food, or as directed by your qualified health care consultant.

Legal Disclaimer

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. ** Always refer to the manufacturer's label on the product for description, recommended dose and precautions.

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

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Customer Questions & Answers

Customer reviews

4.6 out of 5 stars
4.6 out of 5
1,193 global ratings
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Top reviews from other countries

Client d'Amazon
5.0 out of 5 stars Artichaut
Reviewed in Canada on November 18, 2020
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Rowie
5.0 out of 5 stars とても良いなサプリメントです。ガンにも効くかも。
Reviewed in Japan on July 23, 2019
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李昇株
4.0 out of 5 stars まだはわからないですが、
Reviewed in Japan on April 4, 2020
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Disclaimer: While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Amazon.com assumes no liability for inaccuracies or misstatements about products.