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Jarrow Formulas CDP Choline , Supports Brain Function, 250 mg, 60 Caps

4.2 out of 5 stars 368 customer reviews
About the product
  • Intermediate for the synthesis of phosphatidylcholine, a major constituent of the grey matter of brain tissue
  • Promotes brain metabolism by enhancing the synthesis of acetyl-choline
  • Restores phospholipid content in the brain
  • Affects neuronal membrane excitability and osmolarity
  • Dietary supplement

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Product description

Size:60

Product Profile

The basic neural building blocks become less readily available and are less efficiently utilized as the brain ages. One reason this occurs is because the same age-related changes to the vascular system that diminish heart function can also negatively affect the blood supply to the brain. In fact, many other factors involved in mental decline reflect undesirable changes in the body at large. It would seem that a healthy body really does help lead to a healthy mind. Yet although the causes of mental decline are diverse, a few basic changes are common to most forms of deterioration that specifically affect the brain. Reduced synthesis of necessary neurotransmitters, decreased circulation, and diminished cellular efficiency are all the enemies of sound memory and mental clarity. Perhaps surprisingly, phospholipids influence all of these areas critical to brain health.*


Distinguishing Feature:

  • 250 mg of Citicoline [stabilized CDP Choline (cytidine 5’diphosphocholine)] per capsule
Citicoline And How It Is Clinically Supported

Citicoline (cytidine 5’-diphosphocholine) is a molecule that consists of cytidine and choline joined together by a diphosphate bridge. Once citicoline is ingested, it is broken down into its component parts, and these readily cross into the brain and central nervous system. Both components are incorporated into the phospholipid fraction of the cell membrane and organelles, such as mitochondria. Once there, the components of citicoline act as precursors for the biosynthesis of structural phospholipids (e. g. phosphatidylcholine, phosphatidylethanolamine, and phosphatidylserine) in neuronal membranes, support cerebral metabolism, and stimulate the production of neurotransmitters.* Indeed, increased levels of phosphatidylcholine, noradrenaline, acetylcholine, and dopamine have been observed in animal administered citicoline. *

Clinical research has demonstrated a reactivation of brain mitochondrial ATPases and the Na+/K+ ATPases (involved in producing energy) when citicoline is consumed by humans.* Cholinergic compounds, such as acetylcholine, also play significant roles in learning and memory. As such, citicoline has been evaluated in the areas of verbal memory, object recognition, recall, and overall cognitive performance.*

What Else Does Citicoline Do?

Researchers have theorized that citicoline may also be effective in helping brain cells prevent the buildup of different toxins.* Such effects reflect not just the impact of citicoline upon the synthesis of acetylcholine, dopamine and noradrenaline, but also its indirect impact upon membrane health and transport regulation.*

Citicoline, or stabilized CDP Choline (cytidine 5’diphosphocholine), is a naturally occurring intermediate involved in the synthesis of phosphatidylcholine, a major constituent of the grey matter of brain tissue.* Citicoline consumption promotes brain metabolism by enhancing the synthesis of acetyl-choline, restoring phospholipid content in the brain, which positively affects memory and other brain activity.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


Product details

Size: 60
  • Product Dimensions: 6 x 5 x 4 inches
  • Shipping Weight: 0.3 ounces (View shipping rates and policies)
  • Domestic Shipping: Currently, item can be shipped only within the U.S. and to APO/FPO addresses. For APO/FPO shipments, please check with the manufacturer regarding warranty and support issues.
  • International Shipping: This item is not eligible for international shipping. Learn More
  • ASIN: B0013OUJPS
  • UPC: 790011200123 885244928286 747235225739
  • Item model number: CDP
  • Average Customer Review: 4.2 out of 5 stars 368 customer reviews
  • Amazon Best Sellers Rank: #8,580 in Health & Household (See Top 100 in Health & Household)
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Important information

Safety Warning
Keep Out of the Reach of Children

Ingredients
Citicoline (Cognizin) (from stabilized cytidine 5'-diphosphocholine), Silicon dioxide, magnesium stearate (vegetable source) and cellulose. Capsule consists of gelatin.

Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. Please see our full disclaimer below.

Customer Questions & Answers

Customer reviews

Top customer reviews

on May 7, 2014
Size: 120|Verified Purchase
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on December 7, 2015
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on January 21, 2016
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on November 23, 2013
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on September 19, 2014
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on October 11, 2014
Size: 60|Verified Purchase
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on August 2, 2015
Size: 120|Verified Purchase
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on August 4, 2014
Size: 120|Verified Purchase
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Disclaimer: While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Amazon.com assumes no liability for inaccuracies or misstatements about products.