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Jarrow Formulas Natural Source Pterostilbene, Supports Cardiovascular & Neurologic Health, 50 Mg, 60 Veggie Caps

3.8 out of 5 stars 185 customer reviews

About the product
  • Sirtuin activator
  • Calorie restriction mimetic
  • Cardiovascular and neurologic health

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Product description

Product Profile

Pterostilbene (terro-STILL-bean) is found naturally in blueberries, grapes, and in the bark of the Indian Kino Tree (Pterocarpus marsupium). The name Pterocarpus derives from ancient Greek and means “wing fruit”, referring to the shape of the seedpods in this genus. Preparations of the Indian Kino Tree have been used in Ayurvedic medicine for centuries in relation to inflammation and blood-sugar balance. Similarly, resveratrol, a structural cousin of pterostilbene, has been touted for effects related to the heart.*

Pterostilbene vs. Resveratrol

Pterostilbene has been shown to have the same antioxidant potential as resveratrol in a standard assay of antioxidant potential (Trolox). However, the two methylated hydroxyl groups make pterostilbene more lipophilic and less susceptible to conjugation-induced degradation; this leads to a greater half-life in the body compared to resveratrol (105 vs. 14 minutes). These specific structural differences seem to make resveratrol more adept at combating reactive oxygen species (ROS) in whole blood and lymphocytes and pterostilbene better at targeting extracellelular ROS.* Such extracellular ROS are often responsible for tissue damage with imbalanced inflammatory response, amongst other things. As such, pterostilbene and resveratrol tend to be more complementary in their action than competitive. Work in animals has even suggested synergies between the two, along with quercetin. This is one reason both are included, along with quercetin and other components found in grapes, in a related Jarrow Formulas product: Resveratrol Synergy.

Distinguishing Features:

  • 99% pure dimethylresveratrol
  • 50 mg pterostilbene per serving
Matters Of The Heart*

Reduced oxidative stress and a properly modulated inflammatory response seem to be at the root of enduring health, particularly cardiovascular health. In vitro and animal studies suggest pterostilbene has positive effects on multiple inflammation-related biomarkers.* But as we know, a healthy heart and network of blood vessels also involves balanced levels of blood lipids and blood sugar. It’s understood that chronically high plasma levels of glucose lead to advanced glycation end products (AGE), which in turn cause the deterioration of bodily tissues, and an increased risk of developing insulin resistance. Pterostilbene seems to offer some protection from AGEs and may offer defense against metabolic change associated with elevated blood sugar.* When it comes to blood-lipids, pterostilbene has been found to activate peroxisome proliferator-activated receptor alpha (PPARa). PPARa is involved with blood-lipid regulation, synthesis, and metabolism; in vitro and animal studies suggest that through this interaction pterostilbene can have positive effects on blood-lipids.*

Tip-Top Brain Health*

Emerging research suggests that pterostilbene may have something to offer brains too. For instance, pterostilbene may help to defend against a decrease in release of the neurotransmitter dopamine following exposure to an oxidative stressor (hydrogen peroxide).* In rats, pterostilbene leads to a decrease in the distance traveled and a decrease in the time to get to a platform between two trials in the Morris water maze test (i. e. suggesting memory support).* How this may work remains an open question, but it is known that PPARa agonists, like pterostilbene, confer a protective effect on cortical areas of the brain, like the hippocampus.* So it’s possible a similar mechanism could be at the root of both brain and cardiovascular effects.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


Product details

  • Product Dimensions: 1.8 x 1.8 x 3.2 inches
  • Shipping Weight: 0.6 ounces (View shipping rates and policies)
  • Domestic Shipping: Currently, item can be shipped only within the U.S. and to APO/FPO addresses. For APO/FPO shipments, please check with the manufacturer regarding warranty and support issues.
  • International Shipping: This item is not eligible for international shipping. Learn More
  • ASIN: B005ACNW5S
  • UPC: 790011200406 767644684927
  • Item model number: PTERO
  • Average Customer Review: 3.8 out of 5 stars 185 customer reviews
  • Amazon Best Sellers Rank: #1,809 in Health & Household (See Top 100 in Health & Household)
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Important information

Safety Warning
If you have a medical condition (especially diabetes or being treated for glucose control), are pregnant, lactating, trying to conceive, under the age of 18, or taking medications, consult your health care practitioner before using this product.

Indications
• Sirtuin Activator* • Calorie Restriction Mimetic* • Cardiovascular & Neurologic Health*

Ingredients
trans-Pterostilbene (Dimethylresveratrol)(from Pterocarpus marsupium)(Silbionol),Cellulose, silicon dioxide and magnesium stearate (vegetable source). Capsule consists of hydroxypropylmethylcellulose.

Directions
Take 1 capsule per day or as directed by your qualified health care consultant.

Legal Disclaimer
Please note, this product has a "best if used by" date of 09/2016

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

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Customer Rating 4 out of 5 stars (185) 4 out of 5 stars (32) 3 out of 5 stars (85) 4 out of 5 stars (73) 4 out of 5 stars (22) 4 out of 5 stars (1)
Price $14.99 $25.39 $18.26 $23.99 $29.99 $39.95
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Directions Take 1 capsule per day or as directed by your qualified health care consultant. Suggested Usage: As a dietary supplement, take 1 capsule daily. Take 1 tablet per day with food or juice, or as directed by your qualified health care consultant. Easy-Solv tablets disintegrate within several minutes after ingestion. Dosage: Take 1-2 capsules daily as directed by your healthcare professional. Take 1 to 2 capsules daily or as directed by your healthcare professional. Take one (1) capsule daily with or without food, or as recommended by a healthcare practitioner.
Item Dimensions 1.75 x 1.75 x 3.25 in 1.88 x 1.88 x 3.44 in 6 x 5 x 4 in 2 x 2 x 3 in 2.25 x 2.25 x 4.25 in 2.38 x 2.38 x 4.24 in

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