In the natural health world, the term "yeast" is typically associated in a positive way with "brewer's/nutritional" yeast, or in a negative way with Candida albicans (i.e., as in yeast infections). One association that is not commonly made is "probiotic." Nevertheless, that's exactly what Saccharomyces boulardii is, a beneficial yeast used as a probiotic agent to support gastrointestinal health.* Its most important use is when intestinal flora come under assault, such as during antibiotic use or when traveling.*
Probiotic yeast promotes the health of the intestinal tract, helps protect beneficial microbiota, and enhances immune function*.
Dairy-free formula does not need to be refrigerated. View larger.
Saccharomyces boulardii (S. boulardii) typically reaches a maximum steady state in 3 days when taken orally, but does not multiply in the gut. Less than one percent of the ingested quantity is recovered from stools, indicating that supplementation with S. boulardii should take place regularly to achieve continuing benefits.*
S. boulardii is particularly effective in relation to occasional diarrhea from various causes.* The efficacy of taking S. boulardii orally has been demonstrated in helping to decrease the chances or intensity of traveler's diarrhea, antibiotic-associated diarrhea and some food spoilage related diarrhea.*
In fact, meta-analyses of the pooled results from studies suggest that S. boulardii can decrease the relative risk of antibiotic-associated diarrhea by 57 percent to 63 percent. S. boulardii produces proteases that may help to reduce the negative effects of C. difficile produced toxins A and B.* S. boulardii can also interact with undesirable intestinal microorganisms and reduce their adherence to the intestinal wall.* S. boulardii may also reduce sodium secretion and thereby guard against water-loss from intestinal cells during occasional diarrhea.*
Individuals with a hypersensitive bowel may experience more inflammatory episodes and frequent bowel movements. Taking S. boulardii regularly may help guard against such intrusions in daily life.* Other evidence shows that taking 250 mg S. boulardii three times daily can help maintain better lower intestinal health.*
Although secondary to its effects on gastrointestinal health, S.boulardii may benefit skin health.* In a randomized, double-blind study involving 139 human subjects with noncystic acne, the effectiveness and tolerance of S. boulardii was studied in comparison with a placebo over a maximum period of five months. The results of S. boulardii oral intake were assessed as very good/good in 74.3 percent of the patients receiving the preparation, as compared with 21.7 percent in the placebo group. More than 80 percent of the people in the S. boulardii group were judged to be considerably or completely improved, while the corresponding figure for the placebo group was only 26 percent.*
Mannans are polysaccharides consisting of long-chains of the sugar mannose. They are found abundantly on the surface of human intestinal cells and play a critical role in signaling immune cells. Microorganisms typically use these mannans as footholds in the intestines, so it makes sense that the body has evolved mechanisms to start mobilizing a response at the "point of contact." What's interesting is that mannans are also expressed on the cell walls of S. boulardii. And it's believed that these mannans that coat S. boulardii act as anchor site decoys to unfriendly bacteria, providing one mechanism of action by which S. boulardii helps to protect the digestive tract.*
Mannanoligosaccharides (MOS) are shorter versions of mannans that are similarly non-digestible, chains of mannose units. Structurally, they look like the mannans expressed on cells that line the digestive tract. So it is perhaps not surprising that they also act like mannans in some respects. In fact, microorganisms floating through the digestive tract can bind the ingested, free-flowing MOS "hoping" to get a foothold in the intestines. Instead they are "tricked" into a ride through the digestive system and eventually are flushed from the body. And although this often occurs with bacteria, other microorganisms such as Candida species of yeast are also known to be susceptible to this protective mechanism of MOS.*
Saccharomyces boulardii + MOS provides a synergistic effect in promoting intestinal defense by combining the multi-modal probiotic organism S. boulardii with the added benefits of free-flowing MOS.* S. boulardii promotes the health of the intestinal tract, helps support beneficial microbiota in the intestinal ecosystem, and enhances immune function alone, while MOS assists by helping guard against the adhesion of microorganisms to epithelial cells in the intestines.* Saccharomyces boulardii + MOS is not affected by antibiotics, and does not require refrigeration, i.e., it can be stored at room temperature. Refrigeration will, however, extend the shelf life. Avoid temperatures above 77 F (25 C).
About Jarrow Formulas
Jarrow Formulas' complete line of over 350 nutritional products includes vitamins, minerals, probiotics, standardized herbal concentrates, amino acids, enzymes and enteral nutrition products. Customers can be assured of purity, value and potency when choosing these products.
What's in the Box
Jarrow Formulas Saccharomyces Boulardii + MOS, 90 Vegetarian Capsules.