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Miracle Cure: The Creation of Antibiotics and the Birth of Modern Medicine Library Binding – May 9, 2017
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As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections.
William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born.
Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative—a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity’s relationship with nature since the invention of agriculture ten thousand years ago.
- Print length368 pages
- LanguageEnglish
- PublisherViking
- Publication dateMay 9, 2017
- Dimensions6.3 x 1.19 x 9.3 inches
- ISBN-100525428100
- ISBN-13978-0525428107
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Editorial Reviews
Review
—The Wall Street Journal
“In Miracle Cure, William Rosen tells the lavish story of antibiotics with the flair and skill of a seasoned novelist, portraying his characters as all too-human, the research often fallible but occasionally transcendent. . . . Rosen's chronological approach gives the narrative its fluency; his wit and vivid detail make Miracle Cure an absorbing read. . . . A triumph of science writing that deserves a broad popular audience.”
—Minneapolie Star Tribune
"In this assured chronicle of the twentieth-century antibiotics revolution, William Rosen delivers reams of science at a thrilleresque pace. The experimentalists—Gerhard Domagk and Howard Florey among them—are vividly portrayed, as are the patients cured, the pharmaceutical corporations created and the moment in 1943 when bacteriologist Mary Hunt found the ancestor of all penicillin used today, on a mouldy melon. Antibiotic resistance and putative solutions are given their due, including Michael Fischbach's work on microbial-gene clusters in the human microbiome."
—Nature
“Former publisher and editor Rosen tackles a dazzling chapter of modern medical history in this chronicle of the discoveries that opened the age of antibiotics and gave humankind its first effective tool to fight back in an ‘eons-long war’ with infectious disease… Rosen’s thoughtful, scholarly, and engaging history is a powerful testament to this fight.”
—Publishers Weekly, (starred review)
“A richly documented history of the rise—and threatened future—of antibiotics… An encyclopedic reference for researchers and practitioners but also accessible for general readers due to Rosen's lively depiction of the people, places, and politics that color the history of the fight against infectious disease.”'
—Kirkus Reviews, (starred review)
"Miracle Cure is enthralling. Simply and elegantly, Rosen brings so much vibrancy to this narrative, and the science is gripping from beginning to end. A lucid and fascinating book, Miracle Cure is a must-read for anyone with a curious mind."
—Gilbert King, author of the Pulitzer prize-winning, Devil in the Grove
"Bill Rosen combines detailed analysis with a keen sense of humor to craft a page-turner describing the discovery of penicillin and streptomycin to combat scourges that had plagued man from time immemorial. This seminal historical work also warns the advances made during the antibiotics revolution in the 20th century are precarious and might be reversed if we fail to build upon the legacies of the heroic figures portrayed in Miracle Cure."
—Michael S Kinch, author of A Prescription for Change: The Looming Crisis in Drug Development
"Carefully researched, hugely informative, and immensely entertaining."
—Andreas Wagner, author of Arrival of the Fittest
"William Rosen integrates personal histories and scientific concepts so seamlessly that Miracle Cure reads like a novel—I found it difficult to put down. This definitive history of antibiotics is a must-read for anyone interested in modern medicine.”
—Karl Drlica, Public Health Research Institute, Rutgers University and author of Antibiotic Resistance
“Rosen is a terrific storyteller and engaging stylist . . . He invites us to look beyond our . . . differences and recognize that we too live in a fragile equilibrium with the natural world.”
—The Daily Beast
“Readers will be swept along by the strong current of Mr. Rosen’s good natured erudition.”
—The Economist
“Rosen is a natural and playful storyteller, and his digressions both inform the narrative and lend it an eccentric and engaging rhythm.”
—The New York Times
“Rosen has a facility for the telling anecdote and the quirky aside.”
—Bill Gates
About the Author
Product details
- Publisher : Viking; 1st edition (May 9, 2017)
- Language : English
- Library Binding : 368 pages
- ISBN-10 : 0525428100
- ISBN-13 : 978-0525428107
- Item Weight : 1.39 pounds
- Dimensions : 6.3 x 1.19 x 9.3 inches
- Best Sellers Rank: #1,881,257 in Books (See Top 100 in Books)
- #246 in Laboratory Medicine (Books)
- #2,015 in History of Medicine (Books)
- #6,499 in History & Philosophy of Science (Books)
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At the beginning of each chapter, a story is told of a sick patient. This tells the story of how he or she tried to survive and how they would try to cure certain diseases before the discovery of antibiotics. Nothing seemed to work such as therapeutic efforts or doctors removing at least 60 percent of their patients’ blood. In the case of George Washington in 1799, the former presidents neck was coated with a paste composed of wax and beef fat mixed with an irritant made from the secretions of dried beetles, one powerful enough to raise blisters, which were then opened and drained, apparently in the belief that it would remove the disease-causing poison. Yes, that sounds disgusting I know. I had the same facial expression.
With telling those stories, it gives the reader an idea of how they would try to treat diseases in the past. The survival of a woman named Anne Miller who was about to die from a strep infection, marked the beginning of the antibiotic revolution. She was injected with the world’s entire supply of a new drug: penicillin. Diseases like pneumonia, tuberculosis, and typhoid fever, disease that killed billions of people over thousands of years, were finally treatable, and even curable.
This is a must-read book for anyone interested in the modern, historical, and evolution of medicine. This is a fascinating book and the science is gripping from the beginning to end. It also provides pictures of scientist and their discoveries. Although this book provided the positive of antibiotics, it does not provide the negative effects or the over use of antibiotics. Over all, this book is still worth a read.
Very well written and draws the reader into the science and the personalities that created the “Miracle Cures“. Not an antibiotic textbook, but written for the interested individual who wants to understand more about these drugs. Having spent my entire career in antibiotic R&D in both academia and at multiple pharmaceutical companies, I still very much appreciated his approach in bringing these discovery stories alive.
Many significant grammatical errors which is confusing since author is an editor. Also interchanging typhoid fever and typhus should have been caught by someone. There are better books in this genre.







