- Hardcover: 736 pages
- Publisher: W. H. Freeman; Second Edition edition (February 22, 2002)
- Language: English
- ISBN-10: 0716743825
- ISBN-13: 978-0716743828
- Product Dimensions: 8.8 x 1.1 x 11.1 inches
- Shipping Weight: 3.8 pounds (View shipping rates and policies)
- Average Customer Review: 4.1 out of 5 stars See all reviews (10 customer reviews)
- Amazon Best Sellers Rank: #568,496 in Books (See Top 100 in Books)
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Modern Genetic Analysis: Integrating Genes and Genomes Second Edition Edition
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Top Customer Reviews
Of all these excellent books, I find this one to be the best, and my judgment of the book's quality is from the standpoint of someone who is very involved in the algorithms behind bioinformatics and mathematical biology and is attempting to gain, as quickly as possible, the necessary background in genetics. My review therefore will be primarily addressed to those mathematicians or even physicists who plan on moving into bioinformatics.
To relative newcomers to genetics such as myself, the learning of molecular biology and genetics can involve a huge amount of memory work. To the more mathematically-inclined reader, the memorization of facts can be most unpalatable.Read more ›
The second edition of 'Modern Genetic Analysis' is very similar to the first edition, and only about ten percent of the material (at most) has been changed. Most of the problem sets are the same, but have been renumbered. This is actually a teaching advantage because it gives students the option of buying used copies of the first edition rather than new copies of the second.
One major improvement in the second edition, however, is the addition of internet-based genetics tutorials. Students are directed to the various public genome databases on the internet, used by real researchers, and are given practice assignments to do. They are shown how to conduct gene and protein homology searches, how to find open reading frames, and how to access other forms of information from the various public domain databases on the internet. Since internet databases have now become one of the most important tools available to geneticists these tutorials are a welcome addition to this textbook. I highly recommend it.
Greg Doheny (Vancouver, Canada)
THE DIFFICULTY is that this works well up through the cracking of the genetic code in the mid-1960s. Thereafter, genetics and molecular biology proliferate in so many directions that it is no longer possible to provide a linear historical narrative. Worse (or better) yet, the biotechnology and genomics revolutions of the last ten years have opened so many interesting doors that there is simply no time in an introductory course to take whole or even half lectures for the 'famous name' experiments.
MY COURSE currently begins, "As you all know, DNA is a double-stranded helical molecule that replicates semi-conservatively," a standing broad jump over Watson & Crick, Hershey & Chase, Meselson & Stahl, et al.
MGA is intended to reverse the classic order, to begin with a detailed discussion of the structure and function of DNA, RNA, and protein in producing phenotypes. The molecular phenomena can then be used to explain *why* some gene variants can be called 'recessive' or 'dominant', and how this results in 3:1 ratios. By not presenting mendelian concepts as primary, it is possible to deliver a much more effective teaching approach as to How Gene Work. Problem solving with rough guinea pigs and pink flowers can be supplemented with inferences from bands on gels and ASO spot patterns. I used both editions, up till last year, and had good results.Read more ›
Most Recent Customer Reviews
Though I ordered a used book it was in good condition. Good for the price. One or two pages were loosely attached. Fast shipping. Read morePublished on February 9, 2012 by Arya
The book itself was in a fair condition, lot of writing in the book and the cover was terrible, covered with duct tape!!!!!!!Published on January 27, 2010 by Rachid S. Oumarou
The description of the book said it was in "good" condition, but when I received it (only 2 days later), it didn't look like it had even been opened. Read morePublished on September 25, 2009 by Amber J. Seidel
The processing of the order was very fast and the product was in excellent condition. Thank you!Published on October 28, 2008 by ShannonP30
This book takes a while to get to the point and has a tendency to repeat itself. Aside from all the digressions and redundancy, not a bad read.Published on October 1, 2007 by B. Tanaka