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No More Heart Disease Paperback – January 23, 2002
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Dr. Louis Ignarro discovered "the atom" of cardiovascular health--a tiny molecule called Nitric Oxide. NO, as it is known by chemists, is a signaling molecule produced by the body, and is a vasodilator that helps control blood flow to every part of the body. Dr. Ignarro's findings led to the development of Viagra. Nitric Oxide has a beneficial effect on the cardiovascular system as well.
NO relaxes and enlarges the blood vessels, prevents blood clots that trigger strokes and heart attacks, and regulates blood pressure and the accumulation of plaque in the blood vessels. Dr. Ignarro's current research indicates that Nitric Oxide may help lower cholesterol by facilitating the actions of statin drugs like Lipitor.
The goal of the regimen presented in NO More Heart Disease is to age proof the cardiovascular system, keeping the vascular network clean and elastic through enhanced NO productivity. The plan is easy-to-follow without extreme lifestyle adjustments, involving taking supplements to stimulate Nitric Oxide production, incorporating NO friendly food into the diet, and a moderate exercise program.
- Print length270 pages
- LanguageEnglish
- Publication dateJanuary 23, 2002
- Dimensions5.49 x 0.82 x 8.25 inches
- ISBN-100274872951
- ISBN-13978-0312335823
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Product details
- ASIN : 0312335822
- Publisher : St. Martin's Griffin; First Edition (January 23, 2002)
- Language : English
- Paperback : 270 pages
- ISBN-10 : 0274872951
- ISBN-13 : 978-0312335823
- Item Weight : 2.31 pounds
- Dimensions : 5.49 x 0.82 x 8.25 inches
- Best Sellers Rank: #351,286 in Books (See Top 100 in Books)
- #212 in Cardiovascular Diseases (Books)
- #221 in Cardiology (Books)
- #291 in Heart Disease (Books)
- Customer Reviews:
About the author

In 1998, Dr. Louis Ignarro won the Nobel Prize for Medicine, (along with Robert F. Furchgott and Ferid Murad), for his research discoveries showing the powerful ability of nitric oxide (or NO) to improve cardiovascular health and prevent heart disease. His ground-breaking work— the basis for his 2005 best-selling book, NO More Heart Disease— established Dr. Ignarro as perhaps the world’s leading authority on the nutritional approach to cardiac wellness, along with making possible the development of Viagra.
He holds a Ph.D. in pharmacology, is a distinguished professor of pharmacology at UCLA, and is a part-time professor at King Saud University in Riyadh, Saudi Arabia. Dr. Ignarro has spent more than 30 years as a research scientist; seeking to understand the incredible role that nitric oxide plays in fostering optimal human health. One of his most important discoveries was that antioxidants, which reduce cell damage fromfree radicals, also increase nitric oxide levels by protecting blood vessel walls—which secrete nitric oxide—from damage.
He has received countless awards in addition to his Nobel Prize, including the 2008 Distinguished Scientist Award from the American Heart Association and the 2007 Medal of Merit from the International Academy of Cardiovascular Sciences. He edits the journal Nitric Oxide: Biology and Chemistry, sits on numerous scientific advisory boards, and travels the world speaking to professional and lay audiences about the incredible power of nitric oxide.
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Learn more how customers reviews work on AmazonCustomers say
Customers find the book informative and credible. They describe it as an interesting read that explains the science and medical trials behind the Nobel Prize in simple terms. The book provides good advice on improving heart health through supplements, diet, and exercise. Readers consider it worthwhile and recommend it to others.
AI-generated from the text of customer reviews
Customers find the book informative and credible. It explains the history of nitric oxide in simple terms. The science and medical trials behind it are explained. The nutrition and exercise material is good, but nothing new that you couldn't find in hundreds of books. The book explains the benefits of nitricoxide to heart and vascular health, and gives a regimen to follow.
"...And, he explains each supplement and why it is necessary. Well, I already take lots of supplements so why not add a few more?..." Read more
"...Nitric Oxide is an important discovery, and Ignarro and his colleagues deserve lots of praise for bringing it to our attention." Read more
"...Even if you never buy a single supplement, there is enough wisdom and medical good sense in the book to make it well worth your while -- and it may..." Read more
"...And among other, to me, it was very interesting in the chapter 1 to read about how the Nitric Oxide (NO) and its importance was discovered...." Read more
Customers find the book easy to read and well-written. They say it's a great primer on nitric oxide supplementation, with some technical health information. The author is praised for his writing style and explaining complicated medical concepts in a simple way.
"...He is a great writer and explains some complicated medical information in clear and easy to understand verbiage...." Read more
"...But it's an easy read, and you won't fall asleep, which is more than I can say for some books...." Read more
"It’s a book which both is easy to read and containing much important information...." Read more
"...ENTHUSIASTIC FOUR STARS for a great primer on a very important recent advance in medicine - nitric oxide." Read more
Customers find the book provides good advice on healthy living. They say it explains simple ways to improve heart health, circulatory, and energy levels through supplements, diet, and exercise. The book is easy to read and can increase quality of life and lengthen lives.
"...days and after about a week, I was back to feeling normal again; no aches and pains that I was feeling while taking the meds...." Read more
"...However, he accompanies this with a wealth of good advice -- to eat sensibly, take exercise and avoid stress -- which no critic can possibly find..." Read more
"...and a few other supplements can offer incredible protection for the cardiovascular system...." Read more
"...several times a day, I can see that the mixture knocks my pressure down within minutes...." Read more
Customers find the book provides valuable information at a reasonable price. They recommend it to others.
"...Putting cholesterol aside, this is a really great book and worth your time and money...." Read more
"...is enough wisdom and medical good sense in the book to make it well worth your while -- and it may just save your life." Read more
"...I guess the price is cheap enough where you're paying for the program in the book and not how well (or in this case how poorly) the book is written...." Read more
"...With that on the line, it's worth reading for sure." Read more
Top reviews from the United States
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- Reviewed in the United States on October 25, 2011After reading some of the reviews here, I decided to include my own personal experience with using the supplements suggested in Dr. Ignarro's book "NO More Heart Disease".
I will start from the beginning: about 5 years ago, I was informed by my doctor that my total cholesterol reading was 365, but my blood pressure was not too high 130/82. I also came to find out that heart disease is hereditary in my family. The first thing my doctor wanted to do was put me on a cholesterol lowering medication - a statin. Initally I agreed and began taking it. Within two weeks, I felt a huge difference in my overall health. - I felt weak, tired,and my joints felt stiff. I was 39 at the time but I felt like I aged 20 years in those two weeks. I began doing some research and found out the truth about statins and it compelled me to stop taking them immediately. Not too suprisingly, I began to feel better within a few days and after about a week, I was back to feeling normal again; no aches and pains that I was feeling while taking the meds. I decided that I would try to fix my problem the natural way by modifying my diet, adding in some supplements that are said to help lower cholesterol, and increase my activity level. I felt I was fairly active already - weight training 3 - 4 days a week at that time and I ate pretty healthy to begin with, but obviously something was missing. The next year, I had my blood work done again and I thought for sure I was going to be in the clear, but I only managed to get my cholesterol down to 288. My doctor again strongly urged me to take a statin to lower my cholesterol and I still refused. I was truly frustrated because I was already taking supplements - red yeast rice, garlic, L-argnine, niacin, and a multi vitamin and still my cholesterol was this high. I absolutely did not want to take any cholesterol lowering meds; but at the same time, I was becoming worried about having a stroke or a heart attack, so I knew I had to do something soon.
About a year ago, I came across an advertisement for Dr. Ignarro and I found his website. Long story short, I bought his book and applied the supplementation as he advised. After a few months,I had my blood work done and my total cholesterol was 200 and blood pressure was 114/78. I know those are not perfect numbers, but it is huge for me and I am confident that these changes are the result of following the advice/recommendations in his book. I still need to get my numbers a little lower, but I am so relieved that I did not give in and take the easy way out by going on the meds as my doctor suggested. All in all, I give this book 5 stars, because the supplementation is easy and it absoulutely worked for me.
- Reviewed in the United States on May 18, 2014Every now and then we come across a book that is life changing.
I bought this book for a close friend with heart disease. I decided to read it myself. (I didn't think it was necessary for high blood pressure but wanted to read it before giving it to my friend to make sure it was scientifically sound.) Once I got into this book I realized just how dangerous my blood pressure actually is/was. For over three years my doctors haven't been able to get my pressure down into the normal range. Okay, I do take some serious meds that raise blood pressure and blood sugar. I have focused on other health issues and not stressed over the blood pressure issue.
Dr. Louis Ignarro gives a list of supplements with a dosage range. He doesn't promote a clinic, classes, his own supplements or run any hidden agendas. He is a great writer and explains some complicated medical information in clear and easy to understand verbiage. And, he explains each supplement and why it is necessary.
Well, I already take lots of supplements so why not add a few more? I went to Sprouts and bought what I didn't already have. Some were not the right dosage (one amino acid in particular would have required 4 "horse pills" and I am only taking 2) but I still felt it was worth a try.
Three DAYS later, a bit groggy from sleep, as is my usual practice, I got up to weigh myself, test my blood sugar and then test my blood pressure. I retook my blood pressure. Same numbers and they were all in the normal range! I was stunned. I didn't expect anything for at least three weeks (if at all).
I have tried so many products that didn't work for me or that I realized wasn't the product but the severely restricted diet they encouraged. I do eat the foods suggested by Dr. Ignarro but for whatever reasons my body needs the supplements he suggests.
I tell everyone I know about this book and I hope you or a loved one gets excellent, life-changing results also!
- Reviewed in the United States on August 13, 2005I think this is a great book and would recommend it without hesitation. Nitric Oxide is a really interesting subject and this book helps to explain it really well. The only reason I did not give it 5 stars is because Dr Ignarro understanding of cholesterol is rather traditional, and maybe he should familiarise himself with the research undertaken by Dr Uffe Ravnskov [...] The French for example eat lots of cholesterol and saturated fats, and their heart attack rates are very low by comparison to the USA. However I accept that Dr Ignarro is not trained in cholesterol and so don't want to be unkind. Putting cholesterol aside, this is a really great book and worth your time and money. It does come across as a bit `salesy' which is not what you would expect from someone who has won a Nobel Prize, and this may be off-putting to some readers who take offence if something is too commercial. I suspect some marketing or PR person got involved somewhere along the way with this book and felt it needed hyping up. But it's an easy read, and you won't fall asleep, which is more than I can say for some books. Nitric Oxide is an important discovery, and Ignarro and his colleagues deserve lots of praise for bringing it to our attention.
Top reviews from other countries
R. BransonReviewed in the Netherlands on December 7, 20234.0 out of 5 stars It explains the importance of Nitric Oxide
Despite the fact that Louis Ignarro sold his soul to Herbalife, he did win a shared Nobel prize explaining how arginine converts. He did however never made an actual product. Inspired by Ignarro, Dr. Arne van der Gen, PhD., did when he created Amino Alliance. My doctor put me on Amino Alliance and I immediately slept deep and saw my vascular system improve. Available in Europe and the US.
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marco matacotta cordellaReviewed in Italy on December 23, 20222.0 out of 5 stars Abbastanza deluso.
Nonostante sia scritto da un premio Nobel il libro appare quasi come uno spot pubblicitario per il prodotto (molto caro!) per la salute cardiaca che l'autore ha elaborato per una ditta di integratori.
PatrickReviewed in Canada on May 6, 20195.0 out of 5 stars Better in a few weeks...
THIS therapy is so effective it reduces blood pressure, improves sleep, acts LIKE Viagra and in my 60's makes me feel all over like I've been lifting weights... as 'pumped'. Now I want to use this energy to exercise... etc..
(wink)
BUT, you have to exercise lightly, eat 'better' foods, take the antioxidant catalysts, and the 2 amino acids as 'prescribed'. Simple. Might save your life.
Cheap, and effective, based on REAL science that is free. Buy the book.
Ross J ExtonReviewed in Australia on January 4, 20213.0 out of 5 stars Needs up dating
I purchased this book as I wanted to know more of the Formation of NO with in the body as I have read Caldwell Essielstyn’s Prevent and Reverse Heart disease.
The original edition shows its age, with the author promoting the use of supplements to boost NO formation, when the trend is toward whole foods
It would be great for the author to update his original book
Amazon CustomerReviewed in India on May 30, 20165.0 out of 5 stars Five Stars
this book is excellent for heart and other chronic deseases








