"...an excellent, useful reference for pathologists and scientists interested in mice as models for studying human cancer." (Veterinary Pathology, May 2005)
"…this text would make an excellent resource for any library trying to assist their researchers to know where this field has been and where it is going." (E-STREAMS, April 2005)
From the Back Cover
Mouse Models of Human Cancer provides researchers and students with a complete resource on the subject, systematically presenting the principles, methodologies, applications, and challenges associated with this exciting field. Offering a survey of the latest research and a description of future areas of interest, this text:
- Presents real experimental data
- Describes organ site-specific mouse models
- Clearly identifies suitable models for further drug testing
- Critically analyzes current methodologies and their limitations
- Features numerous recognizable expert contributors
- Lists key Web sites, reagents, and companies
From mouse handling and genetic engineering to preclinical trials, Mouse Models of Human Cancer is a comprehensive guide to using these models and relating them to human disease. Its uniform presentation describes organ-specific models in clinical, imaging, and molecular terms, and lays out the relevant genetics, experimental approaches, histological comparisons with human disease, and conclusions.
Combining stellar chapter authors, rich illustrations, and clear, up-to-date coverage, Mouse Models of Human Cancer is an invaluable resource for advanced students and cutting-edge researchers.