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Osmosis Jones

4.4 out of 5 stars 351 customer reviews

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Editorial Reviews

Bill Murray, Chris Rock, David Hyde Pierce. A hilarious adventure combines live action and animation as a white blood cell and an antibiotic superhero unite to battle an invasion of germs. 2001/color/96 min/PG.

Special Features

  • Behind-the-Scenes Documenatry
  • Behind-the-Scenes Voice Sessions
  • Deleted Scenes
  • "Easter Egg" Hidden Features
  • DVD-ROM "Frank's Gross Anatomy" & more

Product Details

  • Actors: Laurence Fishburne, Chris Rock, David Hyde Pierce, Brandy Norwood, William Shatner
  • Directors: Bobby Farrelly, Peter Farrelly
  • Writers: Marc Hyman
  • Producers: Bobby Farrelly, Aaron Parry, Bradley Thomas, Dennis Edwards, John Walker
  • Format: Anamorphic, Animated, Closed-captioned, Color, Live, NTSC
  • Language: English (Dolby Digital 5.1), French (Dolby Digital 5.1), Spanish (Dolby Digital 2.0 Surround)
  • Subtitles: English, French
  • Dubbed: Spanish
  • Region: Region 1 (U.S. and Canada only. Read more about DVD formats.)
  • Aspect Ratio: 2.35:1
  • Number of discs: 1
  • Rated:
    PG-13
    Parents Strongly Cautioned
  • Studio: Warner Home Video
  • DVD Release Date: November 13, 2001
  • Run Time: 95 minutes
  • Average Customer Review: 4.4 out of 5 stars  See all reviews (351 customer reviews)
  • ASIN: B00005QAQH
  • Amazon Best Sellers Rank: #24,630 in Movies & TV (See Top 100 in Movies & TV)
  • Learn more about "Osmosis Jones" on IMDb

Customer Reviews

Top Customer Reviews

Format: DVD Verified Purchase
I've been a 5th grade teacher for 5 years and have shown this movie each year as a reward after learning about the human body in science/health. The kids, for the most part, really enjoy it. There is just enough nasty stuff in there to gross them out - which they love! As a teacher, I just love the entire analogy of the story - every little cell in the body is working toward the same goal - keeping Frank alive. The kids like it, and I also enjoy it. There are some moments in there that are more adult humor that the kids don't even catch, so I'm able to get a laugh out of it.
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Format: DVD
Osmosis Jones is one of those movies you almost feel like you have to apologize for liking. Well, forget about it, because this is a very funny and downright entertaining movie with no class whatsoever!
The scenes bounce between live acting and full animation, determined by whether we are outside or inside the body of Frank. The casting for this silly and peculiar movie was expertly chosen for both live and voice roles.
Live, we have Bill Murray as Frank, in his most disgusting character since Caddyshack. Chris Elliot plays his brother Bob, and manages to challenge Murray in the "disgusting slob" category. Murray eats a hard boiled egg that landed in monkey doodoo, and thus introduces Thrax into his body, a red-death virus determined to take over Frank and kill him. (voiced by Laurence Fishburne)
Inside of Frank, we go to the animation where Chris Rock is the voice of our hero, a white blood cell named Osmosis Jones. Jones is a detective for the City Of Frank, where William Shatner does the voice for Mayor Phlemming. Jones knows something is wrong, but the Mayor denies any illness could occur in Frank. But just to be safe, he "manually overrides" Frank and has him take a cold pill.
Meet Drix, the huge and snotty cold pill, whose voice is played by David Hyde Pierce (Frazier's brother Niles). Jones and Drix make an unlikely team as they hunt down Thrax and try to stop him from killing Frank.
Nothing is taboo here; they go to the nose and get caught up in the wave of snot when Frank's allergies act up, they travel to The Zit, Frank's hottest new club where Kidney Rock is playing (Kidd Rock), and Jones reminisces about the time he hit the "Panic Button" in Frank's stomach, causing him to vomit all over his daughter Shane's teacher.
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Format: DVD
Osmosis Jones is a really good movie, if a bit... well... disgusting at times.
The plot revolves around a white blood cell named Osmosis Jones (voiced by Chris Rock) who serves as a police officer in the body of a guy named Frank (Bill Murray).
When a dastardly virus named Thrax (voiced by Laurence Fishburne) invades Frank's body, it's up to the immunity force to stop him, and Ozzy is teamed up with a cold tablet named Drixobensomedaphedramine, or Drix for short (voiced by the always-wonderful David Hyde Pierce).
Meanwhile, the pompous blood cell politician in charge of Frank's body, Mayor Phlegmming (voiced by William Shatner), is desperate to win the next election, but he is obviously doing a sub-par job of running Frank's body. His aide (and Ozzy's love interest), Leah, is voiced by Brandy Norwood.

This movie is very amusing in some places, but I had to deduct one star because it is, on occasion, REALLY DARN GROSS. I had to turn my head away from the screen in some places. However, this is by no means a bad movie. I personally consider David Hyde Pierce's portrayal of Drix to be one of the best things in the film (if not the very best), especially when Drix busts a secret mob meeting at a disco and utters the following line, doing some dance steps as he speaks:
"Attention, germs, you are surrounded. Uh-huh, uh-huh. Uh-huh, uh-huh, SURROUNDED!". Trust me, it's worth seeing just for that part.

Overall, Osmosis Jones is definitely worth seeing, and it could also be used to teach an anatomy lesson, because it's very accurate. Just watch out for the gross bits.
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Format: VHS Tape
Osmosis Jones is a pretty cool movie that is composed of 1/3 Gross Out Comedy, 1/3 Satire and 1/3 Buddy action flick. And 2/3 are done well. Let's face it, the real life part stunk, but the rest of it more than makes up for it.
This is the story of a guy named Osmosis Jones, a white blood cell voiced by Chris Rock. He lives inside the body of Frank, a slobby zookeeper who's body is likened to a city: it has it's dump (guess where), power plant (heart), ghetto (liver), and even natural disasters (cramps and sicknesses.) So when Frank injests a hard boiled egg that has been in the mouth of a monkey and on the ground, it's bad news. Especially when the egg hosts the Red Death virus named Thrax (my favorite character), voiced superbly by a evilly suave and utterly unrecognizable Laurence Fishburne. Thrax wants to kill Frank in record time (48 hours) by damaging his hypothermis gland and heating Frank up like "A sidewalk on a summer day..." Thrax snickers.
To help Osmosis fight Thrax, enter the by-the-book and not particularly bright cherry-flavored cold pill Drix (David Hyde Peirce)who wants to prove his worth by curing Frank.
The In-Jokes, such as taking you're girlfriend down to the kidneys to see the stones and an armpit being a sauna for gangsters make it funny. The live-action parts are disgusting with vomit jokes and require fast forwarding. And the action scenes near the end, involving car chases and fistfights, are just cool. It's a little violent within the body; Thrax's sicle-like index finger is used for slicing apart those unfortunate cells that stand in his way and for setting fire to his surroundings. Lots of pyromania. Rock, Peirce, and especially Fishburne lend excellent voice talent to this movie. But not for the squeamish.
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