Protein NMR Spectroscopy: Principles and Practice 2nd Edition

by Arthur G. Palmer III (Author), Wayne J. Fairbrother (Author), John Cavanagh (Author),

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ISBN-13: 978-0121644918

ISBN-10: 012164491X

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Protein NMR Spectroscopy, Second Edition combines a comprehensive theoretical treatment of NMR spectroscopy with an extensive exposition of the experimental techniques applicable to proteins and other biological macromolecules in solution.

Beginning with simple theoretical models and experimental techniques, the book develops the complete repertoire of theoretical principles and experimental techniques necessary for understanding and implementing the most sophisticated NMR experiments.

Important new techniques and applications of NMR spectroscopy have emerged since the first edition of this extremely successful book was published in 1996. This updated version includes new sections describing measurement and use of residual dipolar coupling constants for structure determination, TROSY and deuterium labeling for application to large macromolecules, and experimental techniques for characterizing conformational dynamics. In addition, the treatments of instrumentation and signal acquisition, field gradients, multidimensional spectroscopy, and structure calculation are updated and enhanced.

The book is written as a graduate-level textbook and will be of interest to biochemists, chemists, biophysicists, and structural biologists who utilize NMR spectroscopy or wish to understand the latest developments in this field.

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Editorial Reviews

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"This volume is a comprehensive introduction to the methodology required for NMR studies of proteins." --JOURNAL OF MAGNETIC RESONANCE

"Protein NMR Spectroscopy: Principles and Practice covers a huge range of topics related to NMR....A fine two-semester course could be built on this very thorough book. Any student currently using NMR could benefit from the Cavanagh et al. text, which provides an in-depth explanation that is suitable as a resource for even a knowledgeable spectroscopist." --NATURE STRUCTURAL BIOLOGY

"All in all, I find the book very, very good. It will fill an important void in the literature/material available in the NMR field.....There are many 'hands on' secrets that will be very valuable to those beginning in the field as well as those who are 'old hands.' It has a distinct advantage over other books in that is was written as a whole, freshly from cover to cover; it is NOT a collection of published articles hurriedly put together with a nice binding." --DALE F. MIERKE, UNIVERSITY OF MASSACHUSETTS, AMHERST

"Along with detailed explanations of the mechanisms underlying the modern NMR experiments, the book also brings some "order" to the bewildering array of novel NMR pulse sequences. To practitioners of biomolecular NMR, it will prove invaluable for years to come." --STRUCTURE

Review

Key resource for NMR Spectroscopy!

Publisher ‏ : ‎ Academic Press; 2nd edition (November 17, 2006)
Language ‏ : ‎ English
Hardcover ‏ : ‎ 912 pages
ISBN-10 ‏ : ‎ 012164491X
ISBN-13 ‏ : ‎ 978-0121644918
Item Weight ‏ : ‎ 2.93 pounds
Dimensions ‏ : ‎ 6 x 1.88 x 9 inches

Best Sellers Rank: #1,448,992 in Books (See Top 100 in Books)
- #197 in Biophysics (Books)
- #417 in Cell Biology (Books)
- #686 in Molecular Biology (Books)

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elliotkw09

Must Have for Protein NMR Spectroscopists

Reviewed in the United States on August 26, 2015

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This book is one of the best NMR texts I have read. That being said, it is also one of the most challenging NMR texts I have read (it's a tie between this and Intro to SSNMR by Melinda Duer). This book is definitely not a beginners book, so if you are just starting to learn about NMR buy something more basic like Spin Dynamics by Levitt or Understanding NMR by Keeler and read it first. I have yet to find a protein NMR text out there as good as this one. The detail in which Dr. Palmer goes into is fantastic while still being very understandable. More than anything I appreciate the depth in which he covers the different experiment types. This is a must have for anyone doing protein NMR work.

3 people found this helpful

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Ryan_R

thicker than origonal

Reviewed in the United States on January 12, 2014

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The book is rich of knowledge. It covers advanced ideas. The book authors are alphabetical, and anyone in the field refers to it as the Palmer book...He sacrificed his research as an asst. prof to write such a great book. Great discussion of Bloch and how T1 and T2 were originally proposed. I recommend this book along side the Malcom Levitt book (Spin Dynamics). The amazon copy of this book has different paper than other copies in my lab. It is thicker and heavier, but better for writing on or annotating. Other copies in the lab with the older paper have a hard time writing on it. The binding is real crappy, I left it in the lab with that huge orgo encyclopedia sitting on the first 20 pages so it would stay open. I would have really appreciated a paperback version, but they don't make one. Note there is significant differences between the first and second editions, don't cheap out you will be sorry. Get this one.

3 people found this helpful

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Alexandre Esadze

Good for Advanced NMR

Reviewed in the United States on July 26, 2010

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Book is good and comprehensive it has some problems with typeos like mixed or missig indexes in equations, but otherwise its fine. It is not intended as an introductory book beginers are advised to avoid using this book unless they have good background in quantum and statistical physics

One person found this helpful

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Weicheng Li

Five Stars

Reviewed in the United States on March 3, 2017

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It's a really good book to understand and manipulate pulse sequence.

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Another brick in the wall

Four Stars

Reviewed in the United States on March 9, 2016

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Good book. However the flow of concepts is bit difficult to grasp initially. Would love to read gradually.

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Anna

Bad quality

Reviewed in the United States on October 26, 2019

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The book is in really bad condition

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chia-hsiu

I don't like some marker scratch left on "all" edges of the

Reviewed in the United States on November 3, 2014

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fast. However, I don't like some marker scratch left on "all" edges of the books

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genious

Excelent

Reviewed in the United States on April 30, 2012

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Excellent book for NMR beginners but also for experienced users. Very useful when setting up NMR expriments. I widely recommend the purchase of this book.

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Trent Franks

but is still one of the best references for ssNMR spectroscopists

Reviewed in the United Kingdom on June 19, 2018

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Essential for anyone studying protein NMR as a primary focus of their research. It is more helpful for both solution NMR than solid-state NMR, but is still one of the best references for ssNMR spectroscopists. There is an exhaustive compilation of solution NMR experiments and the theoretical treatment for most if you feel like making a new experiment. There is a deep treatment of just about every aspect of solution NMR, from relaxation and dynamics to assignments and structure calculations.

Johnny5

Make sure the product is printed RIGHT SIDE UP!

Reviewed in Canada on June 18, 2012

Verified Purchase

I purchased this book earlier in the year. Using it more as a reference, I didn't bother to go through the whole book. That was MY mistake. By the time the return date had expired, I realized too late that some of the pages were printed the WRONG WAY. Pages 727-758 were all upside down however in the correct order (but I guess if you were reading it upside down the pages would be backwards). Also, the pages that were upside down were not bound correctly and were more prone to fall out. So if you do intend to buy this book, I would HIGHLY recommend flipping through all the pages before the return date to make sure to get a perfect product. Cheers!

One person found this helpful

Luís

A classic renewed

Reviewed in Germany on December 25, 2019

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Exactly what I expected from this book. All the information of the previous edition brought up to date. Very very good.

DNA

Excelente libro

Reviewed in Spain on March 9, 2017

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Un libro de referencia en RMN.
Excellent book, I recommend it. Is one of the NMR bibles, but not for beginners.

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