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Protein-Protein Interactions: A Molecular Cloning Manual 2nd Edition

5.0 5.0 out of 5 stars 1 rating

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This is an updated edition of a manual that provides a thorough collection of the technical and theoretical issues involved in the study of protein associations, including standard methods, biophysical approaches, and, in a final section, a collection of computational methods for integrating and analyzing interactions.

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Editorial Reviews

Review

"...a good combination of well-established and innovative approaches to study protein interactions." Marissa Vignali, University of Washington (The Quarterly Review of Biology) "The book deserves to land on the shelves of many labs and offices. In this new age of proteomics, it might even become a 'must have'." --Trends in Cell Biology

Product details

  • Publisher ‏ : ‎ Cold Spring Harbor Laboratory Press; 2nd edition (October 26, 2005)
  • Language ‏ : ‎ English
  • Paperback ‏ : ‎ 938 pages
  • ISBN-10 ‏ : ‎ 0879697237
  • ISBN-13 ‏ : ‎ 978-0879697235
  • Item Weight ‏ : ‎ 2.31 pounds
  • Dimensions ‏ : ‎ 11 x 1.4 x 8.5 inches
  • Customer Reviews:
    5.0 5.0 out of 5 stars 1 rating

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Top review from the United States

Reviewed in the United States on January 25, 2006
This second edition is much changed from the first edition of 2002. Most of the chapters in the earlier have been either extensively revised and brought up to date or replaced with new chapters (the old chapters are still available on a special web site).

The format of the book is the same with forty-six chapters written by the leading researchers in the field. The chapters are grouped into sections as follows:

1. Protein-Protein Interactions in Biological Context

2. Standard Technologies to Probe Protein Interactions

3. Biophysical Approaches to Probe Protein Interactions

4. Novel High-Throughput Approaches to Probe Protein Interactions

5. Interactions of Proteins and Peptides

6. InVivo Imaging of Protein Interactions

7. Genome-wide and Computer-based Analysis of Protein Interactions

8. Design of Novel Interactions and Inhibitors in Drug Discovery

This book is a summary of the state of the art in the field and is significantly improved over the first edition.
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