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Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves Hardcover – October 2, 2012

4.5 4.5 out of 5 stars 340 ratings

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Editorial Reviews

Review

The Scientist
“[A]n important and surprisingly accessible book, magisterially structured to intertwine the accelerated history of synthetic biology with its precedents in humanity's earlier technological revolutions and in the epochal evolution of life itself. The book packs in a superb short course on life's molecular workings, enabling the reader to grasp how we can actually contemplate resurrecting mammoths and Neanderthals, brewing biofuel from seawater and sunlight, engineering total immunity to viral infection, storing data in DNA, and more.”

Nathan Myhrvold, Founder and CEO, Intellectual Ventures
“A delightfully opinionated, visionary and controversial romp through synthetic biology, which is one of the most important technologies of our time."

Science News
“Reading the first book penned by Church, a Harvard biologist and polymath, is like falling down a rabbit hole straight into his fermenting brain. Church's wide-ranging career includes developing novel methods for reading the genetic instruction manual, or genome, of creatures from bacteria to humans. Now he focuses on synthesizing those instructions from scratch.... [A] dizzying survey of how scientists have unearthed the secrets of living organisms and are now using that information to revamp life itself.”

Robert T. Gonzalez, io9
“[A] phenomenal read.”

Wall Street Journal
“A definitive account of the advances and business ventures that define this new science [of synthetic biology]…. When history is written centuries from now, it is more likely that writing DNA will be the most enduring innovation [of our age].”

New Scientist
“Bold and provocative… Church and Regis offer a behind-the-scenes look at synthetic biology, a rapidly emerging field that is reprogramming the genetic code to create organisms and functions not found in nature.
Regenesis tells of recent advances that may soon yield endless supplies of renewable energy, increased longevity and the return of long-extinct species.”

Nature
“The life sciences emerge as the new high-tech in this paean to synthetic biology…. Each step in the genome's evolution serves as a springboard for expositions of how synthetic biology will revolutionize renewable energy, multivirus resistance, and more.”

Mike Loukides, O'Reilly Radar
“If there's one book that can turn this movement into a full-blown revolution, this is it.”

Derek Jacoby, O'Reilly Radar
“George Church and Ed Regis pull off an exciting and speculative romp through the field of synthetic biology and where it could take us in the not too distant future….
Regenesis provides an accessible and engaging introduction to the revolutionary potentials of synthetic biology and should be of interest to both experts and a general science audience.”

Eric Topol, Professor of Genomics, The Scripps Research Institute, and author of The Creative Destruction of Medicine
“Literally reinventing nature could provide solutions to intractable problems with the energy supply, global warming, and human health. In
Regenesis, George Church, a pioneer and pre-eminent force in promoting our ability to read DNA sequence, now guides us to the future: writing DNA sequence. Teaming up with Ed Regis, Church provides a mind-bending, tour de force account of how this seventh industrial revolution will take hold, and how ultimately the survival of our planet and the human species may rely upon rewriting the code of life. An enthralling journey into the future—with truly profound implications—that should not be missed.”

Stewart Brand, author of Whole Earth Discipline
“Here you will find the bleeding, screaming, thrilling edges of what is becoming possible with genomic engineering, handsomely framed in the fine-grained fundamentals of molecular biology. It is a combination primer and forecast of what is coming in this ‘century of biology' from the perspective of a leading pioneer in the science.”

Kirkus Reviews
“[An] authoritative, sometimes awe-inspiring book…. A valuable glimpse of science at the edge.”

About the Author

George Church is Professor of Genetics at the Harvard Medical School and member of the Wyss Institute of Biologically Inspired Engineering. He is the director of the Lipper Center for Computational Genetics, the Harvard DOE Genomes-to-Life Center, the NIH Center for Excellence in Genomic Science, and PersonalGenomes.org. Church was the driving force behind the Polonator G.007, a low-cost automated genomic sequencing machine. He lives in Brookline, Massachusetts.

Ed Regis is author of seven science books, most recently What Is Life?: Investigating the Nature of Life in the Age of Synthetic Biology. He lives in Sabillasville, Maryland.

Product details

  • Publisher ‏ : ‎ Basic Books; 1st edition (October 2, 2012)
  • Language ‏ : ‎ English
  • Hardcover ‏ : ‎ 304 pages
  • ISBN-10 ‏ : ‎ 0465021751
  • ISBN-13 ‏ : ‎ 978-0465021758
  • Reading age ‏ : ‎ 13 years and up
  • Grade level ‏ : ‎ 8 and up
  • Item Weight ‏ : ‎ 1.15 pounds
  • Dimensions ‏ : ‎ 6.25 x 1.25 x 9.5 inches
  • Customer Reviews:
    4.5 4.5 out of 5 stars 340 ratings

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George Church is Professor of Genetics at Harvard Medical School, Director of PersonalGenomes.org, providing the world's only open-access information on human genome & trait data. His 1984 Harvard PhD included the first direct genome sequencing, molecular multiplexing & barcoding. These lead to the first commercial genome sequence (pathogen, Helicobacter pylori) in 1994. His innovations in "next generation" genome sequencing & synthesis & cell/tissue engineering resulted in 12 companies including medical genomics (Knome, Alacris, AbVitro, GoodStart, Pathogenica) & synthetic biology (LS9, Joule, Gen9, Warp Drive) as well as new privacy, biosafety & biosecurity policies. Honors include election to NAS & NAE and Franklin Bower Laureate for Achievement in Science.

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