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Seeking Health Active B12 with L-5-MTHF, 60 Lozenges, Vitamin B12 Supplement, Supports Cellular Health, Cognitive Health, and Healthy Energy Levels, Vegan- and Vegetarian-Friendly B12 Vitamin, MTHFR
| Price: | $21.95$21.95 ($21.95$21.95 / Count)
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| Price: | $20.85 ($20.85 / Count) $19.76 ($19.76 / Count) |
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| Brand | Seeking Health |
| Item Form | Lozenges |
| Primary Supplement Type | Vitamin B12 |
| Diet Type | Vegan |
| Flavor | Cherry |
About this item
- HEALTHY ENERGY LEVELS: Active B12 with L-5-MTHF by Seeking Health provides 1,360 mcg DFE (800 mcg) of pure non-racemic L-methylfolate in an easy-to-take lozenge, along with two active “coenzyme” forms of vitamin B12 to give you the energy you need.*
- HEALTHY MOOD AND FOCUS: Experience a supported healthy mood, focus, energy, and clarity. Note: This is a situational supplement; only take it when you feel that you need it. Other than those times, don’t take it, or as directed by your healthcare professional.*
- IDEAL FOR MTHFR GENE MUTATION: By taking this combination of methylated nutrients—methylfolate and methylcobalamin—in Active Vitamin B12 with L-5-MTHF, your methylation pathway is supported and your MTHFR gene mutation symptoms are supported.*
- LOZENGE: This easy-to-take and great-tasting lozenge isn’t your typical daily supplement. You should take it on an as-needed basis, or as directed by your healthcare professional. When you have a slight brain fog or feel unfocused, or fatigued, start with a small portion.*
- CONSISTENT QUALITY: At Seeking Health, every ingredient is carefully sourced, researched, and tested. Each meets strict specifications for manufacturing standards before any ingredient is allowed for use. We use only the highest-quality ingredients.
Additional Details
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Product Description
At Seeking Health, we believe there is a fundamental step missing, almost 100% of the time, in today’s healthcare system. A consistent focus on treating symptoms, rather than building health, can mean that you cycle in and out of symptoms and “treatment” over and over, sometimes for years.
Our approach is to support and optimize your digestion, reduce environmental exposure and toxic burden and diet optimization so nutrients can flood in and allow our body to do what it does best - Heal.
Bioavailable B12*
L-5-MTHF for methylation and mood support*
Active B12 with L-5-MTHF contains methylated forms of folate (methylfolate) and B12 (methylcobalamin). These bioactive forms provide the methyl groups necessary for methylation. The process of methylation supports healthy brain function, a positive mood, and heart health.*
- Bioavailable, methylated folate and B12 in a well-absorbed lozenge*
- Potent methylation, homocysteine, and MTHFR support*
- Supports optimal mental clarity and brain health*
Who Needs Active B12 with L-5-MTHF?
Many individuals struggle to adequately absorb folate and B12. Active B12 with L-5-MTHF provides these nutrients in a well-absorbed lozenge for immediate support.* Active B12 with L-5-MTHF supports healthy methylation, homocysteine regulation, and energy production. It provides methylfolate and active B12, which can bypass the MTHFR gene to support genetic mutations.*
Key Ingredients
- True Folate: Features the methylated form of folate, methylfolate (L-5-MTHF) as Quatrefolic (6S)-5-methyltetrahydrofolate, glucosamine salt. Methylfolate is essential for healthy methylation, fetal development, energy, homocysteine regulation, cognition, and much more.*
- Bioavailable B12: A mixture of ‘Adeno’ and ‘Methyl’ forms are included. These coenzymes support energy production and help utilize folate in methylation processes.*
Why Does Active B12 with L-5-MTHF Work?
Active B12 with L-5-MTHF was formulated based on enzymatic pathways that are involved in methylation. Enzymes in these pathways require specific nutrients as cofactors. Arguably, the most critical of these nutrients are active and bioavailable forms of folate and B12.*
How Do I Use Active B12 with L-5-MTHF?
- Take 1 lozenge daily, or use as directed by your healthcare professional. Lozenge may be broken into smaller pieces if lower dosage is desired. Do not take within 5 hours of bedtime as it may interfere with sleep.
Who Needs It?
What's In It?
Why Does it Work?
How do I use it?
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At Seeking Health, every ingredient is carefully sourced, researched, and tested. Each meets strict specifications for manufacturing standards before any ingredient is allowed for use. We only use the highest-quality ingredients. |
Active B12 with L-5-MTHF is free of GMOs, Gluten, Artificial Colors, Artificial Flavors, Artificial Preservatives, Dairy, Egg, Fish, Shellfish, Tree Nuts, Peanuts, Wheat, and Soy. |
Active B12 with L-5-MTHF lozenges are intended for those seeking a potent B12 and folate formula to support healthy methylation. It is great for older adults seeking/desiring cognition and energy support, those with MTHFR gene concerns, or those wanting to support healthy homocysteine levels.* |
Active B12 with L-5-MTHF contains methylated forms of folate (methylfolate) and B12 (methylcobalamin). These bioactive forms provide the methyl groups necessary for methylation. The process of methylation supports healthy brain function, a positive mood, and heart health.* |
How to Enhance
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Consider PulsingDr. Ben Lynch recommends using certain supplements based on your need for them. Start with a partial serving and increase slowly over time to the full serving, only if needed. When you start feeling good, consider reducing the serving size, skipping days, or pausing supplementation. Then take again when you feel you need it (stressful day, traveling, chemical exposure, etc.), hence “pulsing.” Work with your qualified healthcare practitioner to determine what’s best for you. |
Pairs Well WithOptimal Magnesium, to support methylation-dependent enzymes.* B-Minus, to provide the rest of your essential B vitamins. This formula is free from B12 and folate.* PQQ, to support normal oxidative stress levels in your methylation pathways.* |
Clean Your GenesThough supplements may benefit you immensely, they are only one step of your health journey. In his best-selling book, Dirty Genes, Dr. Ben Lynch describes the Clean Genes Protocol. Combining supplements with this protocol may help promote optimal epigenetic health.* |
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| Hydroxo B12 with Folinic Acid | Active B12 5000 | L-5-MTHF Lozenge | |
| Serving Size | 1 Lozenge | 1 Lozenge | 1 Lozenge |
| Total Servings | 60 | 60 | 60 |
| Delivery Method | Chewable | Chewable | Chewable |
| Ingredient Highlights | Low-allergen formula. Potent methyl-free B12 and folate. | Low-allergen formula. Healthy methylation and MTHFR support.* | Low-allergen formula. May help support bone, immune & circulatory health. Powerful methylation, MTHFR, and homocysteine support.* |
| Potency | 1360 mcg DFE (800 mcg) Folate | 1000 mcg B12 | 5000 mcg Vitamin B12 | 1700 mcg DFE (1000 mcg) Folate |
| Vegetarian | |||
| Dairy Free | ✓ | ✓ | ✓ |
| Soy Free | ✓ | ✓ | ✓ |
Product details
- Is Discontinued By Manufacturer : No
- Product Dimensions : 3 x 3 x 3 inches; 0.81 Ounces
- Date First Available : May 10, 2012
- Manufacturer : Seeking Health
- ASIN : B00822JNTC
- Best Sellers Rank: #8,889 in Health & Household (See Top 100 in Health & Household)
- #42 in Vitamin B12 Supplements
- Customer Reviews:
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This item Seeking Health Active B12 with L-5-MTHF, 60 Lozenges, Vitamin B12 Supplement, Supports Cellular Health, Cognitive Health, and Healthy Energy Levels, Vegan- and Vegetarian-Friendly B12 Vitamin, MTHFR | 365 by Whole Foods Market, Vitamin B12 500MCG, 50 Lozanges | Amazon Brand - Solimo Vitamin B12 500 mcg - Normal Energy Production and Metabolism, Immune System Support - 100 Gummies (2 Gummies per Serving) | Amazon Elements Vitamin B12 Methylcobalamin 5000 mcg - Normal Energy Production and Metabolism, Immune System Support - 2 Month Supply (65 Berry Flavored Lozenges) | Amazon Elements Vitamin K2 100 mcg, Vegan, 65 Capsules, 2 month supply (Packaging may vary) | |
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| Customer Rating | 4.7 out of 5 stars (2238) | 4.5 out of 5 stars (620) | 4.7 out of 5 stars (3793) | 4.6 out of 5 stars (7968) | 4.6 out of 5 stars (930) |
| Price | $21.95$21.95 | $5.29$5.29 | $7.39$7.39 | $14.04$14.04 | $8.79$8.79 |
| Shipping | FREE Shipping on orders over $25.00 shipped by Amazon or get Fast, Free Shipping with Amazon Prime | FREE Shipping on orders over $25.00 shipped by Amazon or get Fast, Free Shipping with Amazon Prime | FREE Shipping on orders over $25.00 shipped by Amazon or get Fast, Free Shipping with Amazon Prime | FREE Shipping on orders over $25.00 shipped by Amazon or get Fast, Free Shipping with Amazon Prime | FREE Shipping on orders over $25.00 shipped by Amazon or get Fast, Free Shipping with Amazon Prime |
| Sold By | Seeking Health | Amazon.com | Amazon.com | Amazon.com | Amazon.com |
| Age Range Description | Adult | Adult | — | — | — |
| Brand Name | Seeking Health | 365 by Whole Foods Market | Solimo | Amazon Elements | Amazon Elements |
| Diet Type | Vegan | Vegetarian, Vegan | Vegan | Vegan | — |
| Item Form | Lozenges | Lozenges | Gummy | Lozenges | Capsule |
| Primary Supplement Type | Vitamin B12 | Vitamin-b | Vitamin B12 | Vitamin B12 | Vitamin K2 |
| Specific Uses For Product | Energy | — | — | — | — |
Videos
Videos for this product

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Active B12 with L-5 MTHF
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Designs for Health
Designs for Health
Important information
Safety Information
Children and pregnant or lactating women should consult their healthcare practitioner prior to use. Do not use if tamper seal is damaged. Consult with a healthcare professional before use if you are using antibiotics or other medications.
Indications
As each individual may have different needs for vitamin B12 and folate, the potent doses of these vitamins contained in Active B12 with L-5-MTHF may not be ideal for everyone. Working with a qualified healthcare professional is the best way determine the appropriate dose for your individual needs. The lozenges can be broken down into halves or quarters if a lower dose is desired.
Ingredients
Folate (as Quatrefolic 6S-5-methyltrahydrofolate) - 800 mcg, Vitamin B12 (80% as methylcobalamin and 20% as adenosylcobalamin) - 1000 mcg, Xylitol, ascorbyl palmitate, natural cherry flavor, and silica.
Directions
Take 1 lozenge daily, or as directed by your healthcare practitioner. Lozenge may be broken into smaller pieces if lower dosage is desired.
Legal Disclaimer
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Please contact your healthcare professional immediately if you experience any unwanted side effects. The information contained herein is for informational purposes only and does not establish a doctor-patient relationship. Please be sure to consult your physician before taking this or any other product.
Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.
Customer reviews
Customer Reviews, including Product Star Ratings help customers to learn more about the product and decide whether it is the right product for them.
To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. It also analyzed reviews to verify trustworthiness.
Learn more how customers reviews work on AmazonReviewed in the United States on February 12, 2019
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Then it closes with "Questions? Thoughts? Concerns? Or just want to say hi at any time, please reply to this email." YES, I'm writing to say HI and please stop messing with people's mental health by sending nonsense emails. I am going to attempt to order L-5-MTHF from another company and attempt get my mom to take it when she exits the tailspin she went into on reading this message from the company. Full message from the email is copied below.
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Hi Customer,
Thank you for purchasing Active B12 with L-5-MTHF Lozenges! I’m excited for you to experience the power of Seeking Health supplements.
My name is Dr. Ben Lynch, and I’m the founder and owner of Seeking Health. I want to welcome you to our Seeking Health family, and personally thank you for trusting us with your business.
I know how tough it can be making a purchase decision especially when it comes to supplements and your health.
You can rest assured that you’ve made a wise decision when selecting Seeking Health.
Here are some of the highlights of Active B12 with L-5-MTHF:*
- Contains 1000 mcg of a superior blend vitamin B12 consisting of adenosylcobalamin and methylcobalamin. We use Ferrer’s MecobalActive, which is a methylcobalamin sourced from microbial fermentation for superior bioavailability.
- Does not use the solvent hexane as most forms of methylcobalamin do.
- Considered one of the cleanest and most absorbable forms of B12.
- Uses 800 mcg of the Gnosis form of methylfolate as Quatrefolic® which is more stable than calcium forms of methylfolate.
The xylitol base is derived from North American hardwood such as birch trees—not GMO corn.
Here are some tips to optimize your experience with Active B12 with L-5-MTHF.
How to take:*
- Do not take within 5 hours of bedtime.
- When you feel the urge for caffeine or sugar, consider taking this instead.
- Great to take after a long day of traveling to a different time zone, a high protein meal, a night of drinking, or the next morning after a poor night’s sleep.
- Start with a smaller amount as this is a potent supplement.
- To start out, consider cutting or biting in half or even quarters, and allow it to dissolve in your mouth, then swallow.
- May see results within 30 seconds to 5 minutes such as supported mood, focus, energy, or clarity.
- Place in mouth. Allow to dissolve slowly, then swallow. Tune into how you are feeling—tired, foggy head, out of it, lack of focus.
- As it dissolves, keep tuning into how you are feeling. You may feel the changes quite quickly in your head: a healthy clarity, focus, positive mood, energized.
- Once you feel the way you want to feel, note how much you dissolved. Maybe you only dissolved ¼ or ½ of a lozenge. That may be all you need—make a mental note of that.
Be mindful:*
- Only take on days where you feel you need it. This is not a supplement you need to take every day at the same time forever. This is a supplement that you take when you feel you need it.
- Do not take this supplement if you are already feeling great.
What to expect:*
- Within 30 seconds to 5 minutes, you may experience positive changes in your mood, focus, energy, and clarity
- Initially, you may find you need more and feel great each time you take it.
-Over time, say a few days or a week, you may feel a bit worse. This is because you have replenished your stores and don’t need as much. Stop taking it for now.
- If and when your original symptoms return (and often they will at some point), take the same amount you originally did.
This is not a supplement you have to take every single day at the same time. You’ll learn when to take it, how much, and how often.
Possible side effects:
Stop if you feel worse from taking it. You’ll know.
- Common symptoms of when you’ve taken enough and need to remove the lozenge from your mouth or stop taking it for a day or more include anxiety, headache, itchy skin, joint pain, irritability, insomnia, or runny nose.
- Anxiety and headaches sometimes occur in those who are sensitive to methylated nutrients. If you experience these symptoms, talk to your healthcare professional about taking a non-methylated form instead. We also offer a non-methylated Folinic Acid with Hydroxo B12 lozenge as a bioavailable alternative.
I- f you notice side effects, stop taking Active B12 with L-5-MTHF and consider trying 50 milligrams of niacin which can help to resolve side effects, as niacin plays a role in removing methyl groups from the body. Always consult with your healthcare professional before starting any new supplement.
Other supportive supplements to optimize your experience:*
Optimal Electrolyte is highly recommended to use alongside Active B12 with L-5-MTHF to support healthy hydration levels.
Optimal Liposomal Glutathione Plus or Optimal Liposomal Glutathione may be needed as well to support healthy glutathione levels, the body’s master antioxidant. Consider just a few drops every other day for a few weeks.
Thank you again for choosing Active B12 with L-5-MTHF. When it comes down to it, our mission at Seeking Health is to optimize lives by making great products, providing practical health education, and serving you with friendly customer support.
Questions? Thoughts? Concerns? Or just want to say hi at any time, please reply to this email.
In health,
Dr. Ben Lynch
President of Seeking Health and author of the bestselling book DIRTY GENES
*These statements are not evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
I saw in the "questions" area that people were asking about yeast and why it doesn't say "yeast-free" ...I can probably help with this and will explain --- the reason it doesn't say "yeast-free" is likely due to xylitol in the inactive ingredients, although there is likely no yeast remaining and minimal to no yeast proteins.
This product is a lozenge, so I felt safer trying it, although it doesn't specifically say yeast-free, but due to my science background and understanding of manufacturing practices, I assumed the risk was very low, since B12 is generated via bacterial fermentation, and xylitol is the culprit here (to why it doesn't say "yeast-free"), as it can be produced using bacterial fermentation, yeast fermentation, mixed cultures of both, or fungi, or enzymatic reactions, but there should be no yeast in the end product that is sold as food-grade xylitol for companies to use in their products.
To try this product, I broke one lozenge into 4 pieces and put 1/4th piece inside of my lip between lower teeth and lip. An allergy doctor told me to do this to try things if it should be safe, but if I am unsure, since that is a highly vascular region with thin skin where absorption is quick, so you'd know from skin changes/mouth feeling if it is not safe, could reverse with medication at that point, and would not have ingested it into digestive system.
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Manufacturing B12 and Xylitol...
Let's start with B-12:
Vitamin B12 that is laboratory made uses bacterial fermentation, like Lactobacillus strains. (Not yeast fermentation --- yeasts cannot make B12). Luckily, yeasts do not create B12...so would not be used in manufacturing of B12.
Moving to Xylitol...
Xylitol is a sugar alcohol, it's complex to produce commercially...there are a variety of steps to create D-Xylose, and from here, Xylitol is produced from D-Xylose using either yeast, bacteria, fungi, or mixed cultures of both yeast and bacteria, or enzymatic reactions... so the supplier of xylitol for this product likely doesn't say it's yeast-free, but even if yeasts were used, yeast would be separated and removed in the creation of food-grade xylitol. Most xylitol manufacturing, if using yeast-containing cultures, would use Candida yeast strains (which most people cannot be allergic to, since naturally in our bodies and on our skin, our body keeps these in certain levels since we need but also don't want over-growth) but this would be removed in processing steps, anyway.
Most yeast allergies are to Saccharomyces strains, which aren't usually used in xylitol processing because they yield much less xylitol at the end compared to Candida strains.
There is also a chance that the xylitol is produced using a completely different process (hydrolysis, but that involves a lot of solvents, reagents, purification steps and separation steps and was expensive so companies began looking into ways using the above explained microbiology practices using micro-organisms) and there is no yeast involved at all in the hydrolysis super manufacturing of xylitol... but we'd need the company to tell us where they source their Xylitol from, and we could look that up about which processes they used.
Top reviews from other countries
I don't know if folate in the form of L-5-MTHF is actually better, I personally don't have the MTHF genetic mutation, but some people swear by these tablets
Disclaimer: While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Amazon.com assumes no liability for inaccuracies or misstatements about products.



























