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Thorne B-Complex #12 - Vitamin B Complex with Active B12 and Folate - 60 Capsules
Price: | $20.90 ($0.35 / Count) $19.80 ($0.33 / Count) |
Purchase options and add-ons
Brand | Thorne Research |
Item Form | Capsule |
Primary Supplement Type | Vitamin-b |
Diet Type | Gluten Free |
Flavor | Unflavored |
About this item
- Nervous System: Promotes an optimally functioning nervous system
- Cellular Energy: B vitamins promote cellular energy production by supporting the conversion of carbohydrates into energy, as well as the optimal metabolism of fats and proteins
- Complete Formula: An optimal balance of eight B vitamins with extra vitamin B12, plus choline, in their active forms to enhance absorption in the body
- Free From: Doesn't contain gluten, eggs, tree nuts, peanuts, dairy, soy, fish, or shellfish
- Trusted: Thorne is chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of 11 U.S. Olympic Teams
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Product Description


Thorne's B-Complex #12 contains an optimal balance of B vitamins, with extra B12 and folate. Unlike many multi-B formulas, B-Complex #12 contains the active forms of the B vitamins for optimal utilization by the body.*
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Unique FormulaUnlike many multi-B vitamin supplements, B-Complex #12 contains the active forms of several of the eight water-soluble B vitamins. |
Well-Researched BenefitsThe B vitamins in Thorne's B-Complex #12 support mood, cellular energy production, and brain and nerve health.* |
Designed for SensitivitiesThe ingredients in B-Complex #12 are not derived from yeast like many other B vitamin supplements. |
Greater AbsorptionThe bioactive forms of the B vitamins in each capsule ensures you will get the most bioavailable vitamin B complex available.* |

The potential for adverse impacts on neurological health (the health of the brain and nerves) is increasing and becoming more prevalent because of increased lifespans, environmental toxicity, and poor diet with subsequent nutrient deficiencies. It is believed that mitochondrial sufficiency is at the foundation of brain and nerve health. But the mitochondria, the cell’s energy-producing powerhouse, are also a significant source of free radical production, even in healthy individuals. The aging process, poor diet, and environmental toxins can stress the body's built-in antioxidant system, making it less capable of quenching free radicals, such as those produced in the mitochondria. The B vitamins help mitigate these stressors.* Thorne's B-Complex #12 helps maintain good neurological health.*

When the highest standards have been met, Thorne creates higher ones.
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Sourcing Exceptional IngredientsWe develop better standards for higher quality ingredients. Thorne cares deeply about where our ingredients come from. We partner only with suppliers whose practices emphasize quality, science, and responsibility. Better ingredients means better potency, absorption, and digestibility - and ultimately better health. |
Manufacturing the Right WayWe manufacture our own products to ensure full supply chain transparency. For more than 30 years, we have invested in clean manufacturing practices. We refuse to use ingredients that can inhibit absorption. We perform our final production in the United States. Our Charleston, SC facility is third-party certified. |
Four Rounds of TestingWe perform four rounds of testing for each product we manufacture – far above the industry standard. Thorne has invested in two state-of-the-art in-house laboratories that enable us to conduct four rounds of testing, including raw material testing, in-process batch testing, finished product testing, and expiration date stability testing for each lot of product that we manufacture. |
Thinking SustainablyWe're thinking sustainably to protect our environment. We believe the environment should never be compromised for the sake of business gain. At Thorne, we believe that doing our part to protect the environment and its most valuable resources goes hand in hand with our product quality standards. |
Product details
- Is Discontinued By Manufacturer : No
- Product Dimensions : 2.09 x 2.09 x 3.72 inches; 1.76 Ounces
- Date First Available : September 13, 2007
- Manufacturer : Thorne Research
- ASIN : B0797JXKL9
- Best Sellers Rank: #2,550 in Health & Household (See Top 100 in Health & Household)
- #13 in Vitamin B-Complex Supplements
- #296 in Diet & Sports Nutrition
- Customer Reviews:
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Customer Rating | 4.7 out of 5 stars (2519) | 4.6 out of 5 stars (185) | 4.6 out of 5 stars (3094) | 4.7 out of 5 stars (305) | 4.6 out of 5 stars (325) | 4.5 out of 5 stars (820) |
Price | $22.00$22.00 | $13.64$13.64 | $15.39$15.39 | $29.49$29.49 | $17.79$17.79 | $13.99$13.99 |
Shipping | FREE Shipping on orders over $25.00 shipped by Amazon or get Fast, Free Shipping with Amazon Prime | FREE Shipping on orders over $25.00 shipped by Amazon or get Fast, Free Shipping with Amazon Prime | FREE Shipping on orders over $25.00 shipped by Amazon or get Fast, Free Shipping with Amazon Prime | FREE Shipping. Details | FREE Shipping on orders over $25.00 shipped by Amazon or get Fast, Free Shipping with Amazon Prime | FREE Shipping on orders over $25.00 shipped by Amazon or get Fast, Free Shipping with Amazon Prime |
Sold By | Pattern. | Amazon.com | Amazon.com | Amazon.com | Amazon.com | Amazon.com |
Brand Name | Thorne Research | Amazon Elements | Amazon Elements | 365 by Whole Foods Market | 365 by Whole Foods Market | 365 by Whole Foods Market |
Item Form | Capsule | Tablet | Capsule | Capsules | Capsule | Tablet |
Primary Supplement Type | Vitamin-b | — | — | Vitamin-b | Vitamin-b | Vitamin-b |
Size | 60 Count (Pack of 1) | 60 | 65 Count (Pack of 1) | 180 Count (Pack of 1) | 90 Count (Pack of 1) | 90 Count (Pack of 1) |
Videos
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Our Point of View on Thorne Research B-Complex Capsules
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Important information
Safety Information
If pregnant, consult your health-care practitioner before using this product. Folinic acid and 5-methyl-tetrahydrofolate supplementation is not recommended concurrently with methotrexate cancer therapy, as they can interfere with methotrexate's anti-neoplastic activity; however, these folate sources have not been shown to interfere with the anti-inflammatory activity of methotrexate.
Indications
Tissue Support, Cellular Support
Ingredients
One Capsule Contains: Thiamin (as Thiamin HCl) 40 mg, Riboflavin (25 mg as Riboflavin and 3.6 mg, Riboflavin 5'-Phosphate Sodium) 28.6 mg, Niacin (as Niacinamide) 80 mg, Vitamin B6 (20 mg as Pyridoxine HCl and 3.4 mg as Pyridoxal 5'-Phosphate) 23.4 mg, Folate (400 mcg as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 668 mcg DFE, Vitamin B12 (as Methylcobalamin) 600 mcg, Biotin 80 mcg, Pantothenic Acid (as Calcium Pantothenate) 45 mg, Choline (as Choline Citrate) 14 mg. Other Ingredients: Hypromellose (derived from cellulose) capsule, Microcrystalline Cellulose, Calcium Laurate, Silicon Dioxide.
Directions
Take 1 capsule one to three times daily or as recommended by a health-care practitioner.
Legal Disclaimer
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Please contact your healthcare professional immediately if you experience any unwanted side effects. The information contained herein is for informational purposes only and does not establish a doctor-patient relationship. Please be sure to consult your physician before taking this or any other product.
Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.
Customer reviews
Customer Reviews, including Product Star Ratings help customers to learn more about the product and decide whether it is the right product for them.
To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. It also analyzed reviews to verify trustworthiness.
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Reviewed in the United States on February 16, 2022
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This particular supplement formulation seems to work for me, my son and my father. I have noticed increased energy and mood stability and less irritability in all of us. And, as for my 90-year-old father, he was on antidepressants for 10 years (as well as on and off of them for the prior 55 years). 2014 blood work showed B12 deficiency, so he started B12 (cyanocobalamin) shots, but saw no improvement, and his antidepressants were gradually increased. In October 2015, his blood work showed he was in range for B12 and folate, but his homocysteine level was high. Because of the research I had done on MTHFR, I knew right away that my dad had an MTHFR mutation, because (1) when blood homocysteine is elevated while B12 and Folate are in the normal range, that indicates the body is not properly converting folic acid to methylated folate and B12 (cyanocobalamin-synthetic form) to methylated B12 (active forms used by the body); (2) I had to get my MTHFR mutation from a parent. The form of B12 in the shots my dad was taking monthly is cyanocobalamin, which is synthetic and cheap and requires properly working MTHFR for conversion. So keep in mind that B12 and folate levels in blood work alone is not an accurate indicator of whether or not the body is actually converting to active forms required for the body to utilize. The addition of a homocysteine test is more revealing. Since my dad started taking Thorne B Complex #12, he is completely off of antidepressants and doing well! His doctors are intrigued and impressed. I gave them the information and hope they will use it to help other patients. Every person is different. It is best to start with lower potency supplements and work your way up to prevent reactions (in my case, reaction to too much methylfolate).
Dr. Ben Lynch has two MTHFR mutations himself, so he has a personal interest in this field. MTHFR.net is a FABULOUS resource for those struggling with MTHFR mutations, or those who want to find out if they have such mutations. It is now believed that at least 50% of the population has some MTHFR variant (SNPs), which can cause a host of problems, including fibromyalgia, miscarriages, severe depression, autism and much more. While there is typically not one “smoking gun” that causes all our ailments, I believe MTHFR is a good place to start. MTHFR.net can tell you which tests to have and where to get them. I hope this helps someone!
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