- Hardcover: 269 pages
- Publisher: McGraw-Hill Companies; 1st edition (January 17, 2001)
- Language: English
- ISBN-10: 0071369805
- ISBN-13: 978-0071369800
- Product Dimensions: 9.2 x 6.3 x 1 inches
- Shipping Weight: 1 pounds (View shipping rates and policies)
- Average Customer Review: 3.5 out of 5 stars See all reviews (8 customer reviews)
- Amazon Best Sellers Rank: #5,720,971 in Books (See Top 100 in Books)
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Transducing the Genome: Information, Anarchy, and Revolution in the Biomedical Sciences Hardcover – January 17, 2001
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What has made the Human Genome Project so deeply appealing? In one sense, it's just another large-scale, big-budget effort to keep a gang of nerds busy and out of trouble for a few years. Geneticist Gary Zweiger looks askance at this and explains how the confluence of information systems, big science, and business exemplified by the HGP is actually accelerating the pace of beneficial change for all people. Transducing the Genome: Information, Anarchy, and Revolution in the Biomedical Sciences draws deeply on Zweiger's experience in biological science and biotech commerce to illuminate the scientific, economic, and legal issues relevant to the search for a more complete understanding of human genetics. Brimming with pro-capitalist optimism, he believes that the information revolution spawned the biotech explosion and will soon lead to better, cheaper solutions to a very broad range of health problems:
Knowledge of our internal information network will come mostly from an explosion of new genomic database analyses. A growing army of mathematicians and information scientists will develop increasingly powerful and more useful algorithms and computational processes for finding biomedical knowledge in these databases. A growing regiment of biologists and medical professionals with training in mathematics and information sciences will lead these knowledge discovery missions.
Zweiger assuages the reader's fears of gene patents with a brief foray into intellectual property law. It does seem unlikely that biotech patents will pose any more problems than standard pharmaceutical company practice. Combining scientific, legal, and business expertise, Transducing the Genome provides the most comprehensive overview of the birth of biotech yet written. --Rob Lightner
"Gary Zweiger...provides a bracing insider's account of why gene structure matters to science and commerce. His focus is on transducing the information content of DNA into useful form. He teases out a powerful theme of genomics: its focus on methods of creating massive databases quickly." - American Scientist; "Transducing the Genome is a captivating overview of genomics. Geneticist Zweiger provides a clearly written and interesting account of the Human Genome Project, major players at the center of genome research, the origin of the genomics industry, the role of leading genomics companies, and the future prospects of the Genome Project.... This enjoyable and compelling story on genomics is har to put down." - Choice --This text refers to an out of print or unavailable edition of this title.
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Top Customer Reviews
Much better book are from Watson and Berry or from Ridley.
Zweiger (employed at the time of writing by Agilent) clearly is writing from a point of view. He strongly believes that the capitalist model will take care of itself and that competition and reward will lead the way to a better future for all. He takes issue with people who oppose genome-related patents, arguing for the general benevolence of the industry and the fraternity of science. While I may (generally) agree with him, I would have preferred that he either shed the disguise of neutrality on the subject and explain his personal point of view or that he present more compelling arguments from the "other side". Most of the counter-points that he raises in the question of patenting are straw men and far too easy for him to dismiss.
While the book was very interesting, I was also a little bit lost in the structure from time to time. While the individual chapters were excellent reading, I felt that the whole did not hang together as well as it should have or could have.
This would make a particularly good book if you are interested in the biotechnology industry and the ethical issues surrounding the debate between non-profit and private sector science.